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The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

Cell biochemistry and function, 2024-04, Vol.42 (3), p.e3998-e3998

2024

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Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

Archivos españoles de urología, 2024-03, Vol.77 (2), p.183-192

2024

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Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2024-02, Vol.75 (1)

2024

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Excessive Tryptophan and Phenylalanine Induced Pancreatic Injury and Glycometabolism Disorder in Grower-finisher Pigs

The Journal of nutrition, 2024-04, Vol.154 (4), p.1333-1346

2024

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Gadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms

Nature communications, 2024-04, Vol.15 (1), p.2989-2989

2024

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The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts

Scientific reports, 2024-03, Vol.14 (1), p.7559-7559

2024

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Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway

BMC cancer, 2024-04, Vol.24 (1), p.408-408

2024

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Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis

Respiratory research, 2024-04, Vol.25 (1), p.160-160

2024

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PQR309, a dual PI3K/mTOR inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma

Cell death & disease, 2024-03, Vol.15 (3), p.237-237

2024

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UBE2C promotes the proliferation of acute myeloid leukemia cells through PI3K/AKT activation

BMC cancer, 2024-04, Vol.24 (1), p.497

2024

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The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na+/K+-ATPase

Molecular biology reports, 2024-04, Vol.51 (1), p.517-517

2024

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The protective effect and mechanism of glycosides of cistanche deserticola on rats in middle cerebral artery occlusion (MCAO) model

Journal of Toxicology and Environmental Health, Part A, 2024-05, Vol.87 (10), p.448-456

2024

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Targeting myocardial inflammation: investigating the therapeutic potential of atrial natriuretic peptide in atrial fibrosis

Molecular biology reports, 2024-04, Vol.51 (1), p.506-506

2024

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Transglutaminase 3 regulates cutaneous squamous carcinoma differentiation and inhibits progression via PI3K-AKT signaling pathway-mediated Keratin 14 degradation

Cell death & disease, 2024-04, Vol.15 (4), p.252-252

2024

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OPN silencing reduces hypoxic pulmonary hypertension via PI3K-AKT-induced protective autophagy

Scientific reports, 2024-04, Vol.14 (1), p.8670-8670

2024

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Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma

Cellular & molecular biology letters, 2024-04, Vol.29 (1), p.50-50

2024

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RACGAP1 promotes lung cancer cell proliferation through the PI3K/AKT signaling pathway

Scientific reports, 2024-04, Vol.14 (1), p.8694-8694

2024

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Nanoquercetin and Extracellular Vesicles as Potential Anticancer Therapeutics in Hepatocellular Carcinoma

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.638

2024

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SIRT1 and ZNF350 as novel biomarkers for osteoporosis: a bioinformatics analysis and experimental validation

Molecular biology reports, 2024-12, Vol.51 (1), p.530

2024

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A prognostic model of idiopathic pulmonary fibrosis constructed based on macrophage and mitochondria-related genes

BMC pulmonary medicine, 2024-04, Vol.24 (1), p.176-176

2024

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MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway

Functional & integrative genomics, 2024-04, Vol.24 (2), p.71-71

2024

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RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway

Cell communication and signaling, 2024-04, Vol.22 (1), p.227-227

2024

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Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation

BMC complementary medicine and therapies, 2024-04, Vol.24 (1), p.150-150

2024

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Origin, evolution, and diversification of inositol 1,4,5-trisphosphate 3-kinases in plants and animals

BMC genomics, 2024-04, Vol.25 (1), p.350-350

2024

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Regulatory mechanisms of autophagy on DHA and carotenoid accumulation in Crypthecodinium sp. SUN

Biotechnology for biofuels and bioproducts, 2024-04, Vol.17 (1), p.50-50

2024

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The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

Excessive Tryptophan and Phenylalanine Induced Pancreatic Injury and Glycometabolism Disorder in Grower-finisher Pigs

Gadd45g insufficiency drives the pathogenesis of myeloproliferative neoplasms

The cyclooxygenase-2 upregulation mediates production of PGE2 autacoid to positively regulate interleukin-6 secretion in chronic rhinosinusitis with nasal polyps and polyp-derived fibroblasts

Knockdown of NCAPD3 inhibits the tumorigenesis of non-small cell lung cancer by regulation of the PI3K/Akt pathway

Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis

PQR309, a dual PI3K/mTOR inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma

UBE2C promotes the proliferation of acute myeloid leukemia cells through PI3K/AKT activation

The involvement of Akt, mTOR, and S6K in the in vivo effect of IGF-1 on the regulation of rat cardiac Na+/K+-ATPase

The protective effect and mechanism of glycosides of cistanche deserticola on rats in middle cerebral artery occlusion (MCAO) model

Targeting myocardial inflammation: investigating the therapeutic potential of atrial natriuretic peptide in atrial fibrosis

Transglutaminase 3 regulates cutaneous squamous carcinoma differentiation and inhibits progression via PI3K-AKT signaling pathway-mediated Keratin 14 degradation

OPN silencing reduces hypoxic pulmonary hypertension via PI3K-AKT-induced protective autophagy

Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma

RACGAP1 promotes lung cancer cell proliferation through the PI3K/AKT signaling pathway

Nanoquercetin and Extracellular Vesicles as Potential Anticancer Therapeutics in Hepatocellular Carcinoma

SIRT1 and ZNF350 as novel biomarkers for osteoporosis: a bioinformatics analysis and experimental validation

A prognostic model of idiopathic pulmonary fibrosis constructed based on macrophage and mitochondria-related genes

MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway

RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway

Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation

Origin, evolution, and diversification of inositol 1,4,5-trisphosphate 3-kinases in plants and animals

Regulatory mechanisms of autophagy on DHA and carotenoid accumulation in Crypthecodinium sp. SUN

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