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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Nature communications, 2024-03, Vol.15 (1), p.2612-2612

2024

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Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling

Chemico-biological interactions, 2024-05, Vol.394, p.110968-110968, Article 110968

2024

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PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures

Neoplasia (New York, N.Y.), 2024-05, Vol.51, p.100987-100987, Article 100987

2024

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Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport

Journal of ethnopharmacology, 2024-06, Vol.327, p.117946-117946, Article 117946

2024

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AAV-mediated VEGFA overexpression promotes angiogenesis and recovery of locomotor function following spinal cord injury via PI3K/Akt signaling

Experimental neurology, 2024-05, Vol.375, p.114739-114739, Article 114739

2024

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The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

Cell biochemistry and function, 2024-04, Vol.42 (3), p.e3998-n/a

2024

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PI3Kγδ inhibition suppresses key disease features in a rat model of asthma

Respiratory research, 2024-04, Vol.25 (1), p.175-175

2024

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A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia

Journal of ethnopharmacology, 2024-06, Vol.328, p.118117-118117, Article 118117

2024

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Cannabidiol induces systemic analgesia through activation of the PI3Kγ/nNOS/NO/KATP signaling pathway in neuropathic mice. A KATP channel S-nitrosylation-dependent mechanism

Nitric oxide, 2024-05, Vol.146, p.1-9

2024

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MicroRNA-203a inhibits breast cancer progression through the PI3K/Akt and Wnt pathways

Scientific reports, 2024-02, Vol.14 (1), p.4715-4715

2024

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Enhanced STAT3/PIK3R1/mTOR signaling triggers tubular cell inflammation and apoptosis in septic-induced acute kidney injury: implications for therapeutic intervention

Clinical science (1979), 2024-03, Vol.138 (6), p.351

2024

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The human adenovirus PI3K-Akt activator E4orf1 is targeted by the tumor suppressor p53

Journal of virology, 2024-03, Vol.98 (4), p.e0170123

2024

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Human beta defensin 3 knockdown inhibits the proliferation and migration of airway smooth muscle cells through regulating the PI3K/AKT signaling pathway

Molecular immunology, 2024-04, Vol.168, p.38-46

2024

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Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induces apoptosis in HepG2 cells

PloS one, 2024-03, Vol.19 (3), p.e0300051-e0300051

2024

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Regulation of optimized new Shengmai powder on cardiomyocyte apoptosis and ferroptosis in ischemic heart failure rats: The mediating role of phosphatidylinositol-3-kinase/protein kinase B/tumor protein 53 signaling pathway

Journal of ethnopharmacology, 2024-08, Vol.330, p.118264-118264, Article 118264

2024

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LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway

Zhong hua yi xue za zhi, 2024-03, Vol.104 (10), p.758-765

2024

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Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

Archivos españoles de urología, 2024-03, Vol.77 (2), p.183-192

2024

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PI3Kα inhibitor GNE-493 triggers antitumor immunity in murine lung cancer by inducing immunogenic cell death and activating T cells

International immunopharmacology, 2024-03, Vol.130, p.111747-111747, Article 111747

2024

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GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1

International journal of molecular sciences, 2024-02, Vol.25 (4), p.2068

2024

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Plasmodium falciparum selectively degrades α-spectrin of infected erythrocytes after invasion

mBio, 2024-03, Vol.15 (4), p.e0351023-e0351023

2024

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Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

Journal of integrative neuroscience, 2024-03, Vol.23 (3), p.61

2024

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miR-30a-5p attenuates hypoxia/reoxygenation-induced cardiomyocyte apoptosis by regulating PTEN protein expression and activating PI3K/Akt signaling pathway

BMC cardiovascular disorders, 2024-05, Vol.24 (1), p.236-236

2024

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Effects of electroacupuncture on the PI3K/Akt/CREB signaling pathway and hippocampal neuronal apoptosis in diabetic cognitive impairment rats

Zhēncì yánjiū, 2024-03, Vol.49 (3), p.265

2024

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Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2024-02, Vol.75 (1)

2024

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Campothecin suppresses cell proliferation and migration in head and neck squamous cell carcinoma by blocking RAB27A-mediated phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT) pathway

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2024-04, Vol.75 (2), p.205

2024

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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling

PIK3R1 fusion drives chemoresistance in ovarian cancer by activating ERK1/2 and inducing rod and ring-like structures

Xanthoceras sorbifolium leaves alleviate hyperuricemic nephropathy by inhibiting the PI3K/AKT signaling pathway to regulate uric acid transport

AAV-mediated VEGFA overexpression promotes angiogenesis and recovery of locomotor function following spinal cord injury via PI3K/Akt signaling

The PI3K/AKT/mTOR signaling pathway in breast cancer: Review of clinical trials and latest advances

PI3Kγδ inhibition suppresses key disease features in a rat model of asthma

A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia

Cannabidiol induces systemic analgesia through activation of the PI3Kγ/nNOS/NO/KATP signaling pathway in neuropathic mice. A KATP channel S-nitrosylation-dependent mechanism

MicroRNA-203a inhibits breast cancer progression through the PI3K/Akt and Wnt pathways

Enhanced STAT3/PIK3R1/mTOR signaling triggers tubular cell inflammation and apoptosis in septic-induced acute kidney injury: implications for therapeutic intervention

The human adenovirus PI3K-Akt activator E4orf1 is targeted by the tumor suppressor p53

Human beta defensin 3 knockdown inhibits the proliferation and migration of airway smooth muscle cells through regulating the PI3K/AKT signaling pathway

Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induces apoptosis in HepG2 cells

Regulation of optimized new Shengmai powder on cardiomyocyte apoptosis and ferroptosis in ischemic heart failure rats: The mediating role of phosphatidylinositol-3-kinase/protein kinase B/tumor protein 53 signaling pathway

LncRNA SNHG11 promotes malignant progression of colorectal cancer cells through the PI3K/Akt/mTOR signaling pathway

Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway

PI3Kα inhibitor GNE-493 triggers antitumor immunity in murine lung cancer by inducing immunogenic cell death and activating T cells

GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1

Plasmodium falciparum selectively degrades α-spectrin of infected erythrocytes after invasion

Tanshinone IIA Regulates Synaptic Plasticity in Mg 2+ -Free-Induced Epileptic Hippocampal Neurons via the PI3K/Akt Signaling Pathway

miR-30a-5p attenuates hypoxia/reoxygenation-induced cardiomyocyte apoptosis by regulating PTEN protein expression and activating PI3K/Akt signaling pathway

Effects of electroacupuncture on the PI3K/Akt/CREB signaling pathway and hippocampal neuronal apoptosis in diabetic cognitive impairment rats

Kinetochore scaffold 1 downregulation suppressed the development of non-small cell lung cancer by inactivating the phosphatidylinositol 3 kinase/protein kinase B (AKT)/nuclear factor-kappa B pathway

Campothecin suppresses cell proliferation and migration in head and neck squamous cell carcinoma by blocking RAB27A-mediated phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT) pathway

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