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Association between promoter polymorphisms in anterior pharynx-defective-1a and sporadic Alzheimer's disease in the North Chinese Han population

Neuroscience letters, 2009-05, Vol.455 (2), p.101-104

2009

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Take five-BACE and the γ-secretase quartet conduct Alzheimer's amyloid β-peptide generation

The EMBO journal, 2004-02, Vol.23 (3), p.483-488

Haass, Christian

2004

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Simulating the γ-secretase enzyme: Recent advances and future directions

Biochimie, 2018-04, Vol.147, p.130-135

2018

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Aging of the brain, neurotrophin signaling, and Alzheimer's disease: Is IGF1-R the common culprit?

Neurobiology of aging, 2008-06, Vol.29 (6), p.795-811

Puglielli, Luigi

2008

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OCIAD2 activates [gamma]-secretase to enhance amyloid [beta] production by interacting with nicastrin

Cellular and molecular life sciences : CMLS, 2014-07, Vol.71 (13), p.2561

2014

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OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin

Cellular and molecular life sciences : CMLS, 2014-07, Vol.71 (13), p.2561-2576

2014

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Generation of Amyloid‐β Peptides by γ‐Secretase

Israel journal of chemistry, 2017-07, Vol.57 (7-8), p.574-585

2017

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Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer’s disease

International Journal of Biochemistry and Cell Biology, 2003-11, Vol.35 (11), p.1505-1535

2003

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Presenilin 1 is involved in the maturation of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1)

Journal of neuroscience research, 2007-01, Vol.85 (1), p.153-165

2007

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The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid

Neurochemical research, 2007-04, Vol.32 (4-5), p.609-623

2007

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Germinated brown rice alters A[beta](1-42) aggregation and modulates Alzheimer's disease-related genes in differentiated human SH-SY5Y cells

Evidence-based complementary and alternative medicine, 2015-01, Vol.2015

2015

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TMP21 degradation is mediated by the ubiquitin-proteasome pathway

The European journal of neuroscience, 2008-11, Vol.28 (10), p.1980-1988

2008

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Expression profiles of two human APH-1 genes and their roles in formation of presenilin complexes

Biochemical and biophysical research communications, 2005-02, Vol.327 (1), p.18-22

2005

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Identification and characterization of a novel human APH-1b splice variant lacking exon 4

Biochemical and biophysical research communications, 2005-05, Vol.330 (4), p.1068-1072

2005

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Conserved “PAL” sequence in presenilins is essential for γ-secretase activity, but not required for formation or stabilization of γ-secretase complexes

Neurobiology of disease, 2004-04, Vol.15 (3), p.654-666

2004

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Overexpression of calsenilin enhances γ-secretase activity

Neuroscience letters, 2005-04, Vol.378 (1), p.59-64

2005

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N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53

Biochimica et biophysica acta, 2006-09, Vol.1762 (9), p.802-810

2006

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Loss of nicastrin elicits an apoptotic phenotype in mouse embryos

Brain research, 2006-05, Vol.1086 (1), p.76-84

2006

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Localization of presenilin–nicastrin complexes and γ‐secretase activity to the trans‐Golgi network

Journal of neurochemistry, 2003-03, Vol.84 (5), p.1143-1153

2003

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Interaction between the APOE ɛ4 allele and the APH- 1b c + 651T > G SNP in Alzheimer's disease

Neurobiology of aging, 2008-10, Vol.29 (10), p.1494-1501

2008

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Genetic association between polymorphisms of Pen2 gene and late onset Alzheimer's disease in the North Chinese population

Brain research, 2007-04, Vol.1141, p.10-14

2007

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GPCR, a rider of Alzheimer’s disease

Frontiers in Biology, 2011-08, Vol.6 (4), p.282-288, Article 282

2011

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Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

European journal of biochemistry, 2004-01, Vol.271 (2), p.375-385

2004

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γ‐Secretase: An Unusual Enzyme with Many Possible Disease Targets, Including Alzheimer's Disease

Aspartic Acid Proteases as Therapeutic Targets, 2010, p.325-351

2010

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Association between promoter polymorphisms in anterior pharynx-defective-1a and sporadic Alzheimer's disease in the North Chinese Han population

Take five-BACE and the γ-secretase quartet conduct Alzheimer's amyloid β-peptide generation

Simulating the γ-secretase enzyme: Recent advances and future directions

Aging of the brain, neurotrophin signaling, and Alzheimer's disease: Is IGF1-R the common culprit?

OCIAD2 activates [gamma]-secretase to enhance amyloid [beta] production by interacting with nicastrin

OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin

Generation of Amyloid‐β Peptides by γ‐Secretase

Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer’s disease

Presenilin 1 is involved in the maturation of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1)

The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid

Germinated brown rice alters A[beta](1-42) aggregation and modulates Alzheimer's disease-related genes in differentiated human SH-SY5Y cells

TMP21 degradation is mediated by the ubiquitin-proteasome pathway

Expression profiles of two human APH-1 genes and their roles in formation of presenilin complexes

Identification and characterization of a novel human APH-1b splice variant lacking exon 4

Conserved “PAL” sequence in presenilins is essential for γ-secretase activity, but not required for formation or stabilization of γ-secretase complexes

Overexpression of calsenilin enhances γ-secretase activity

N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53

Loss of nicastrin elicits an apoptotic phenotype in mouse embryos

Localization of presenilin–nicastrin complexes and γ‐secretase activity to the trans‐Golgi network

Interaction between the APOE ɛ4 allele and the APH- 1b c + 651T > G SNP in Alzheimer's disease

Genetic association between polymorphisms of Pen2 gene and late onset Alzheimer's disease in the North Chinese population

GPCR, a rider of Alzheimer’s disease

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations

γ‐Secretase: An Unusual Enzyme with Many Possible Disease Targets, Including Alzheimer's Disease

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