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Clinical Trial Protocol: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy, and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults with Aneurysmal Subarachnoid Hemorrhage [NEWTON-2 (Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After SubarachNoid Hemorrhage)]

Neurocritical care, 2019-02, Vol.30 (1), p.88-97

2019

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Use of recombinant factor VIIa in patients with warfarin-associated intracranial hemorrhage

Neurocritical care, 2005-01, Vol.2 (3), p.263-267

2005

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Middle Cerebral Artery Territory Infarction and Early Brain Swelling: Progression and Effect of Age on Outcome

Mayo Clinic proceedings, 1998-09, Vol.73 (9), p.829-836

1998

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Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study

Journal of cerebral blood flow and metabolism, 2005-06, Vol.25 (6), p.763-774

2005

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A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Phase III Study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III)

International journal of stroke, 2014-06, Vol.9 (4), p.536-542

2014

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pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI)

NeuroImage clinical, 2019-01, Vol.22, p.101736-101736, Article 101736

2019

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Spatial and Temporal Pattern of Ischemia and Abnormal Vascular Function Following Traumatic Brain Injury

JAMA neurology, 2020-03, Vol.77 (3), p.339

2020

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Incidence and Mechanisms of Cerebral Ischemia in Early Clinical Head Injury

Journal of cerebral blood flow and metabolism, 2004-02, Vol.24 (2), p.202-211

2004

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Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection

Intensive care medicine, 2015-05, Vol.41 (5), p.823-832

2015

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Low-Dose Intravenous Heparin Infusion After Aneurysmal Subarachnoid Hemorrhage is Associated With Decreased Risk of Delayed Neurological Deficit and Cerebral Infarction

Neurosurgery, 2021-03, Vol.88 (3), p.523-530

2021

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White Blood Cell Count Improves Prediction of Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage

Neurosurgery, 2019-02, Vol.84 (2), p.397-403

2019

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Emergency Department Neurologic Deterioration in Patients With Spontaneous Intracerebral Hemorrhage: Incidence, Predictors, and Prognostic Significance

Academic emergency medicine, 2012-02, Vol.19 (2), p.133-138

2012

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The SAFARI Score to Assess the Risk of Convulsive Seizure During Admission for Aneurysmal Subarachnoid Hemorrhage

Neurosurgery, 2018-06, Vol.82 (6), p.887-893

2018

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Differences in End-of-Life Care in the ICU Across Patients Cared for by Medicine, Surgery, Neurology, and Neurosurgery Physicians

Chest, 2014-02, Vol.145 (2), p.313-321

2014

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Subarachnoid Hemorrhage Patients Admitted to Intensive Care in Australia and New Zealand: A Multicenter Cohort Analysis of In-Hospital Mortality Over 15 Years

Critical care medicine, 2017-02, Vol.45 (2), p.e138-e145

2017

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Hyperventilation following head injury: Effect on ischemic burden and cerebral oxidative metabolism

Critical care medicine, 2007-02, Vol.35 (2), p.568-578

2007

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Chronic kidney disease in patients with acute intracerebral hemorrhage: association with large hematoma volume and poor outcome

Cerebrovascular diseases (Basel, Switzerland), 2011-01, Vol.31 (3), p.271-277

2011

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Safety and Feasibility of Early Mobilization in Patients with Subarachnoid Hemorrhage and External Ventricular Drain

Neurocritical care, 2019-08, Vol.31 (1), p.88-96

2019

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BOLD MRI and early impairment of cerebrovascular reserve after aneurysmal subarachnoid hemorrhage

Journal of magnetic resonance imaging, 2014-10, Vol.40 (4), p.972-979

2014

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Pericontusional brain tissue exhibits persistent elevation of lactate/pyruvate ratio independent of cerebral perfusion pressure

Critical care medicine, 2007-04, Vol.35 (4), p.1153-1160

2007

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Declining mortality in neurocritical care patients: a cohort study in Southern Alberta over eleven years

Canadian journal of anesthesia, 2013-10, Vol.60 (10), p.966-975

2013

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Los Angeles Motor Scale to Identify Large Vessel Occlusion: Prehospital Validation and Comparison With Other Screens

Stroke (1970), 2018-03, Vol.49 (3), p.565-572

2018

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Clinical Characteristics and Outcomes of Patients with Aneurysmal Subarachnoid Hemorrhage: A Prospective Multicenter Study in a Middle-Income Country

Neurocritical care, 2023-04, Vol.38 (2), p.378-387

2023

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NEWTON-2 Cisternal (Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage): A Phase 2, Multicenter, Randomized, Open-Label Safety Study of Intracisternal EG-1962 in Aneurysmal Subarachnoid Hemorrhage

Use of recombinant factor VIIa in patients with warfarin-associated intracranial hemorrhage

Middle Cerebral Artery Territory Infarction and Early Brain Swelling: Progression and Effect of Age on Outcome

Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study

A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Phase III Study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III)

pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI)

Spatial and Temporal Pattern of Ischemia and Abnormal Vascular Function Following Traumatic Brain Injury

Incidence and Mechanisms of Cerebral Ischemia in Early Clinical Head Injury

Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection

Low-Dose Intravenous Heparin Infusion After Aneurysmal Subarachnoid Hemorrhage is Associated With Decreased Risk of Delayed Neurological Deficit and Cerebral Infarction

White Blood Cell Count Improves Prediction of Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage

Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure

Emergency Department Neurologic Deterioration in Patients With Spontaneous Intracerebral Hemorrhage: Incidence, Predictors, and Prognostic Significance

The SAFARI Score to Assess the Risk of Convulsive Seizure During Admission for Aneurysmal Subarachnoid Hemorrhage

Differences in End-of-Life Care in the ICU Across Patients Cared for by Medicine, Surgery, Neurology, and Neurosurgery Physicians

Subarachnoid Hemorrhage Patients Admitted to Intensive Care in Australia and New Zealand: A Multicenter Cohort Analysis of In-Hospital Mortality Over 15 Years

Hyperventilation following head injury: Effect on ischemic burden and cerebral oxidative metabolism

Chronic kidney disease in patients with acute intracerebral hemorrhage: association with large hematoma volume and poor outcome

Safety and Feasibility of Early Mobilization in Patients with Subarachnoid Hemorrhage and External Ventricular Drain

BOLD MRI and early impairment of cerebrovascular reserve after aneurysmal subarachnoid hemorrhage

Pericontusional brain tissue exhibits persistent elevation of lactate/pyruvate ratio independent of cerebral perfusion pressure

Declining mortality in neurocritical care patients: a cohort study in Southern Alberta over eleven years

Los Angeles Motor Scale to Identify Large Vessel Occlusion: Prehospital Validation and Comparison With Other Screens

Clinical Characteristics and Outcomes of Patients with Aneurysmal Subarachnoid Hemorrhage: A Prospective Multicenter Study in a Middle-Income Country

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