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Clinical Trial Protocol: Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy, and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults with Aneurysmal Subarachnoid Hemorrhage [NEWTON-2 (Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After SubarachNoid Hemorrhage)]

Neurocritical care, 2019-02, Vol.30 (1), p.88-97

2019

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Use of recombinant factor VIIa in patients with warfarin-associated intracranial hemorrhage

Neurocritical care, 2005-01, Vol.2 (3), p.263-267

2005

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Middle Cerebral Artery Territory Infarction and Early Brain Swelling: Progression and Effect of Age on Outcome

Mayo Clinic proceedings, 1998-09, Vol.73 (9), p.829-836

1998

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A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Phase III Study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III)

International journal of stroke, 2014-06, Vol.9 (4), p.536-542

2014

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pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI)

NeuroImage clinical, 2019-01, Vol.22, p.101736-101736, Article 101736

2019

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Spatial and Temporal Pattern of Ischemia and Abnormal Vascular Function Following Traumatic Brain Injury

JAMA neurology, 2020-03, Vol.77 (3), p.339

2020

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Incidence and Mechanisms of Cerebral Ischemia in Early Clinical Head Injury

Journal of cerebral blood flow and metabolism, 2004-02, Vol.24 (2), p.202-211

2004

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Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection

Intensive care medicine, 2015-05, Vol.41 (5), p.823-832

2015

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Low-Dose Intravenous Heparin Infusion After Aneurysmal Subarachnoid Hemorrhage is Associated With Decreased Risk of Delayed Neurological Deficit and Cerebral Infarction

Neurosurgery, 2021-03, Vol.88 (3), p.523-530

2021

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White Blood Cell Count Improves Prediction of Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage

Neurosurgery, 2019-02, Vol.84 (2), p.397-403

2019

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Validation of the 9-Point and 24-Point Hematoma Expansion Prediction Scores and Derivation of the PREDICT A/B Scores

Stroke (1970), 2015-11, Vol.46 (11), p.3105-3110

2015

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Clinical practice and effect of carbon dioxide on outcomes in mechanically ventilated acute brain-injured patients: a secondary analysis of the ENIO study

Intensive care medicine, 2024-02, Vol.50 (2), p.234-246

2024

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Emergency Department Neurologic Deterioration in Patients With Spontaneous Intracerebral Hemorrhage: Incidence, Predictors, and Prognostic Significance

Academic emergency medicine, 2012-02, Vol.19 (2), p.133-138

2012

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Neurocritical care: why does it make a difference?

Current opinion in critical care, 2014-04, Vol.20 (2), p.174-181

2014

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The SAFARI Score to Assess the Risk of Convulsive Seizure During Admission for Aneurysmal Subarachnoid Hemorrhage

Neurosurgery, 2018-06, Vol.82 (6), p.887-893

2018

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Differences in End-of-Life Care in the ICU Across Patients Cared for by Medicine, Surgery, Neurology, and Neurosurgery Physicians

Chest, 2014-02, Vol.145 (2), p.313-321

2014

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miR-27a-3p protects against blood–brain barrier disruption and brain injury after intracerebral hemorrhage by targeting endothelial aquaporin-11

The Journal of biological chemistry, 2018-12, Vol.293 (52), p.20041-20050

2018

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Stability of cerebral metabolism and substrate availability in humans during hypoxia and hyperoxia

Clinical science (1979), 2014-05, Vol.126 (9), p.661

2014

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Subarachnoid Hemorrhage Patients Admitted to Intensive Care in Australia and New Zealand: A Multicenter Cohort Analysis of In-Hospital Mortality Over 15 Years

Critical care medicine, 2017-02, Vol.45 (2), p.e138-e145

2017

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Hyperventilation following head injury: Effect on ischemic burden and cerebral oxidative metabolism

Critical care medicine, 2007-02, Vol.35 (2), p.568-578

2007

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Chronic kidney disease in patients with acute intracerebral hemorrhage: association with large hematoma volume and poor outcome

Cerebrovascular diseases (Basel, Switzerland), 2011-01, Vol.31 (3), p.271-277

2011

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Safety and Feasibility of Early Mobilization in Patients with Subarachnoid Hemorrhage and External Ventricular Drain

Neurocritical care, 2019-08, Vol.31 (1), p.88-96

2019

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NEWTON-2 Cisternal (Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage): A Phase 2, Multicenter, Randomized, Open-Label Safety Study of Intracisternal EG-1962 in Aneurysmal Subarachnoid Hemorrhage

Use of recombinant factor VIIa in patients with warfarin-associated intracranial hemorrhage

Middle Cerebral Artery Territory Infarction and Early Brain Swelling: Progression and Effect of Age on Outcome

A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Phase III Study of Clot Lysis Evaluation of Accelerated Resolution of Intraventricular Hemorrhage (CLEAR III)

pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI)

Spatial and Temporal Pattern of Ischemia and Abnormal Vascular Function Following Traumatic Brain Injury

Incidence and Mechanisms of Cerebral Ischemia in Early Clinical Head Injury

Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection

Low-Dose Intravenous Heparin Infusion After Aneurysmal Subarachnoid Hemorrhage is Associated With Decreased Risk of Delayed Neurological Deficit and Cerebral Infarction

White Blood Cell Count Improves Prediction of Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage

Validation of the 9-Point and 24-Point Hematoma Expansion Prediction Scores and Derivation of the PREDICT A/B Scores

Surgical Performance Determines Functional Outcome Benefit in the Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation (MISTIE) Procedure

Clinical practice and effect of carbon dioxide on outcomes in mechanically ventilated acute brain-injured patients: a secondary analysis of the ENIO study

Emergency Department Neurologic Deterioration in Patients With Spontaneous Intracerebral Hemorrhage: Incidence, Predictors, and Prognostic Significance

Neurocritical care: why does it make a difference?

The SAFARI Score to Assess the Risk of Convulsive Seizure During Admission for Aneurysmal Subarachnoid Hemorrhage

Differences in End-of-Life Care in the ICU Across Patients Cared for by Medicine, Surgery, Neurology, and Neurosurgery Physicians

miR-27a-3p protects against blood–brain barrier disruption and brain injury after intracerebral hemorrhage by targeting endothelial aquaporin-11

Stability of cerebral metabolism and substrate availability in humans during hypoxia and hyperoxia

Subarachnoid Hemorrhage Patients Admitted to Intensive Care in Australia and New Zealand: A Multicenter Cohort Analysis of In-Hospital Mortality Over 15 Years

Hyperventilation following head injury: Effect on ischemic burden and cerebral oxidative metabolism

Chronic kidney disease in patients with acute intracerebral hemorrhage: association with large hematoma volume and poor outcome

Safety and Feasibility of Early Mobilization in Patients with Subarachnoid Hemorrhage and External Ventricular Drain

Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

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