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LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

The Journal of biological chemistry, 2015-05, Vol.290 (22), p.13641-13653

2015

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Conformational dynamics of the TTD–PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability

The Journal of biological chemistry, 2017-12, Vol.292 (51), p.20947-20959

2017

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Revealing the protein propionylation activity of the histone acetyltransferase MOF (males absent on the first)

The Journal of biological chemistry, 2018-03, Vol.293 (9), p.3410-3420

2018

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The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation

The Journal of biological chemistry, 2020-07, Vol.295 (31), p.10535-10559

2020

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The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes

The Journal of biological chemistry, 1995-11, Vol.270 (47), p.28092-28096

1995

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Abstract 2091: Living in the cold without brown adipose tissue lipolysis

The Journal of biological chemistry, 2023, Vol.299 (3), p.103898, Article 103898

2023

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The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases

The Journal of biological chemistry, 2008-03, Vol.283 (10), p.6193-6200

2008

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Cl− and H+ coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl−/H+ exchanger ClC-5

The Journal of biological chemistry, 2020-02, Vol.295 (6), p.1464-1473

2020

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Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues

The Journal of biological chemistry, 1990-08, Vol.265 (23), p.13933-13938

1990

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A Conformational Rearrangement upon Binding of IgE to Its High Affinity Receptor

The Journal of biological chemistry, 1996-08, Vol.271 (32), p.19256-19263

1996

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The Propeptide of the Transforming Growth Factor-β Superfamily Member, Macrophage Inhibitory Cytokine-1 (MIC-1), Is a Multifunctional Domain That Can Facilitate Protein Folding and Secretion

The Journal of biological chemistry, 2001-05, Vol.276 (20), p.16911-16918

2001

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Inactivation of Chloramphenicol by O-Phosphorylation

The Journal of biological chemistry, 1995-11, Vol.270 (45), p.27000-27006

1995

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Enzyme-catalyzed Mechanism of Isoniazid Activation in Class I and Class III Peroxidases

The Journal of biological chemistry, 2004-09, Vol.279 (37), p.39000-39009

2004

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Oncogenic src, raf, and rasStimulate a Hypertrophic Pattern of Gene Expression and Increase Cell Size in Neonatal Rat Ventricular Myocytes

The Journal of biological chemistry, 1998-07, Vol.273 (29), p.18146-18152

1998

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Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity

The Journal of biological chemistry, 2012-09, Vol.287 (37), p.31456-31456

2012

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Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramide

The Journal of biological chemistry, 2011-01, Vol.286 (2), p.1301-1311

2011

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Isotope effects and alternative substrate reactivities for tryptophan 2,3-dioxygenase

The Journal of biological chemistry, 1993-08, Vol.268 (24), p.17781-17786

1993

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Inactivation of chloramphenicol by O-phosphorylation. A novel resistance mechanism in Streptomyces venezuelae ISP5230, a chloramphenicol producer

The Journal of biological chemistry, 1995-11, Vol.270 (45), p.27000-27006

1995

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A Rat Kidney-specific Calcium Transporter in the Distal Nephron

The Journal of biological chemistry, 2000-09, Vol.275 (36), p.28186-28194

2000

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Molecular Cloning and Characterization of a Channel-like Transporter Mediating Intestinal Calcium Absorption

The Journal of biological chemistry, 1999-08, Vol.274 (32), p.22739-22746

1999

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The Propeptide of the Transforming Growth Factor-Î² Superfamily Member, Macrophage Inhibitory Cytokine-1 (MIC-1), Is a Multifunctional Domain That Can Facilitate Protein Folding and Secretion

The Journal of biological chemistry, 2001-05, Vol.276 (20), p.16911

2001

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Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements

The Journal of biological chemistry, 2002-01, Vol.277 (4), p.2916-2922

2002

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Cl - and H + coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl - /H + exchanger ClC-5

The Journal of biological chemistry, 2020-02, Vol.295 (6), p.1464

2020

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Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H super(+)-ATPase Recycling

The Journal of biological chemistry, 2005-03, Vol.280 (9), p.8452-8463

2005

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BCL-3 and NF-ÎºB p50 Attenuate Lipopolysaccharide-induced Inflammatory Responses in Macrophages

The Journal of biological chemistry, 2004-11, Vol.279 (48), p.49995

2004

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LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2

Conformational dynamics of the TTD–PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability

Revealing the protein propionylation activity of the histone acetyltransferase MOF (males absent on the first)

The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation

The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes

Abstract 2091: Living in the cold without brown adipose tissue lipolysis

The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases

Cl− and H+ coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl−/H+ exchanger ClC-5

Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues

A Conformational Rearrangement upon Binding of IgE to Its High Affinity Receptor

The Propeptide of the Transforming Growth Factor-β Superfamily Member, Macrophage Inhibitory Cytokine-1 (MIC-1), Is a Multifunctional Domain That Can Facilitate Protein Folding and Secretion

Inactivation of Chloramphenicol by O-Phosphorylation

Enzyme-catalyzed Mechanism of Isoniazid Activation in Class I and Class III Peroxidases

Oncogenic src, raf, and rasStimulate a Hypertrophic Pattern of Gene Expression and Increase Cell Size in Neonatal Rat Ventricular Myocytes

Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity

Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramide

Isotope effects and alternative substrate reactivities for tryptophan 2,3-dioxygenase

Inactivation of chloramphenicol by O-phosphorylation. A novel resistance mechanism in Streptomyces venezuelae ISP5230, a chloramphenicol producer

A Rat Kidney-specific Calcium Transporter in the Distal Nephron

Molecular Cloning and Characterization of a Channel-like Transporter Mediating Intestinal Calcium Absorption

The Propeptide of the Transforming Growth Factor-Î² Superfamily Member, Macrophage Inhibitory Cytokine-1 (MIC-1), Is a Multifunctional Domain That Can Facilitate Protein Folding and Secretion

Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements

Cl - and H + coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl - /H + exchanger ClC-5

Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H super(+)-ATPase Recycling

BCL-3 and NF-ÎºB p50 Attenuate Lipopolysaccharide-induced Inflammatory Responses in Macrophages

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