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Breast Tumor Heterogeneity: Source of Fitness, Hurdle for Therapy

Molecular cell, 2015-11, Vol.60 (4), p.537-546

2015

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Nicotinamide N‐methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer

The EMBO journal, 2023-07, Vol.42 (13), p.e112559-n/a

2023

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Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer

Cancer research (Chicago, Ill.), 2007-03, Vol.67 (6), p.2420-2424

2007

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Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

Oncogene, 2015-04, Vol.34 (17), p.2272-2278

2015

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Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors

The FEBS journal, 2013-06, Vol.280 (12), p.2758-2765

2013

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ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

eLife, 2023-04, Vol.12

2023

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VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation

Cancer research (Chicago, Ill.), 2014-03, Vol.74 (5), p.1566-1575

2014

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How pregnancy at early age protects against breast cancer

Trends in molecular medicine, 2014-03, Vol.20 (3), p.143-153

2014

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Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

Nature medicine, 2012-04, Vol.18 (4), p.529-537

2012

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Mammary Tumor Formation and Metastasis Evoked by a HER2 Splice Variant

Cancer research (Chicago, Ill.), 2013-09, Vol.73 (17), p.5320-5327

2013

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JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer

Cancer cell, 2012-12, Vol.22 (6), p.796-811

2012

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Selective blockade of NF-kappa B activity in airway immune cells inhibits the effector phase of experimental asthma

The Journal of immunology (1950), 2004-11, Vol.173 (9), p.5766-5775

2004

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A role for the scaffolding adapter GAB2 in breast cancer

Nature medicine, 2006-01, Vol.12 (1), p.114-121

2006

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Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

Breast cancer research : BCR, 2016-04, Vol.18 (1), p.41-41, Article 41

2016

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Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress

Biochemical journal, 2011-09, Vol.438 (2), p.369-378

2011

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Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium

Breast cancer research : BCR, 2013-04, Vol.15 (2), p.R36-R36, Article R36

2013

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The Eleventh ENBDC Workshop: Advances in Technology Help to Unveil Mechanisms of Mammary Gland Development and Cancerogenesis

Journal of mammary gland biology and neoplasia, 2019-09, Vol.24 (3), p.201-206

2019

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Breast cancer prevention: lessons to be learned from mechanisms of early pregnancy-mediated breast cancer protection

Cancer research (Chicago, Ill.), 2015-03, Vol.75 (5), p.803-807

2015

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Targeting PI3K, HER2 and the IL-8/JAK2 axis in metastatic breast cancer: Which combination makes the whole greater than the sum of its parts?

Drug resistance updates, 2013-07, Vol.16 (3), p.68-72

2013

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Thirteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

Journal of mammary gland biology and neoplasia, 2022-12, Vol.27 (3-4), p.233-239

2022

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Luminal Expression of PIK3CA Mutant H1047R in the Mammary Gland Induces Heterogeneous Tumors

Cancer research (Chicago, Ill.), 2011-07, Vol.71 (13), p.4344-4351

2011

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Activating Mutations in Pik3ca Contribute to Anal Carcinogenesis in the Presence or Absence of HPV-16 Oncogenes

Clinical cancer research, 2019-03, Vol.25 (6), p.1889-1900

2019

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The ninth ENBDC Weggis meeting: growth and in-depth characterisation of normal and neoplastic breast cells

Breast cancer research : BCR, 2017-08, Vol.19 (1), p.96-96, Article 96

2017

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Nuclear factor-κB, cancer, and apoptosis

Biochemical pharmacology, 2000-10, Vol.60 (8), p.1085-1089

2000

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Breast Tumor Heterogeneity: Source of Fitness, Hurdle for Therapy

Nicotinamide N‐methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer

Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

Mouse models of PIK3CA mutations: one mutation initiates heterogeneous mammary tumors

ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization

VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation

How pregnancy at early age protects against breast cancer

Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

Mammary Tumor Formation and Metastasis Evoked by a HER2 Splice Variant

JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer

Selective blockade of NF-kappa B activity in airway immune cells inhibits the effector phase of experimental asthma

A role for the scaffolding adapter GAB2 in breast cancer

Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress

Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium

The Eleventh ENBDC Workshop: Advances in Technology Help to Unveil Mechanisms of Mammary Gland Development and Cancerogenesis

Breast cancer prevention: lessons to be learned from mechanisms of early pregnancy-mediated breast cancer protection

Targeting PI3K, HER2 and the IL-8/JAK2 axis in metastatic breast cancer: Which combination makes the whole greater than the sum of its parts?

Thirteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

Patient-derived xenograft (PDX) models in basic and translational breast cancer research

Luminal Expression of PIK3CA Mutant H1047R in the Mammary Gland Induces Heterogeneous Tumors

Activating Mutations in Pik3ca Contribute to Anal Carcinogenesis in the Presence or Absence of HPV-16 Oncogenes

The ninth ENBDC Weggis meeting: growth and in-depth characterisation of normal and neoplastic breast cells

Nuclear factor-κB, cancer, and apoptosis

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