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Mechanism-based cancer therapy: resistance to therapy, therapy for resistance

Oncogene, 2015-07, Vol.34 (28), p.3617-3626

2015

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Stops along the RAS pathway in human genetic disease

Nature medicine, 2006-03, Vol.12 (3), p.283-285

2006

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Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

Nature medicine, 2012-04, Vol.18 (4), p.529-537

2012

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CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

Oncogene, 2015-10, Vol.34 (44), p.5593-5598

2015

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A role for the scaffolding adapter GAB2 in breast cancer

Nature medicine, 2006-01, Vol.12 (1), p.114-121

2006

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Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

Breast cancer research : BCR, 2016-04, Vol.18 (1), p.41-41, Article 41

2016

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Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium

Breast cancer research : BCR, 2013-04, Vol.15 (2), p.R36-R36, Article R36

2013

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NF-κB2/p100 induces Bcl-2 expression

Leukemia, 2003-07, Vol.17 (7), p.1349-1356

2003

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The ninth ENBDC Weggis meeting: growth and in-depth characterisation of normal and neoplastic breast cells

Breast cancer research : BCR, 2017-08, Vol.19 (1), p.96-96, Article 96

2017

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Inhibition of the NF-kappa B transcription factor increases Bax expression in cancer cell lines

Oncogene, 2001-05, Vol.20 (22), p.2805-2813

2001

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Early but not late pregnancy induces lifelong reductions in the proportion of mammary progesterone sensing cells and epithelial Wnt signaling

Breast cancer research : BCR, 2014-03, Vol.16 (2), p.402-402, Article 3380

2014

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Complexity galore: 3D cultures, biomechanics and systems medicine at the eighth ENBDC workshop "Methods in Mammary Gland Development and Cancer"

Breast cancer research : BCR, 2016-11, Vol.18 (1), p.115-115, Article 115

2016

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Hippo inactivation feeds tumor-initiating cells

Breast cancer research : BCR, 2012-08, Vol.14 (4), p.318-318, Article 318

2012

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Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion

Breast cancer research : BCR, 2012-10, Vol.14 (5), p.R131-R131, Article R131

2012

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Assessment of a New Instrument for Detecting Preventable Adverse Drug Reactions

Drug safety, 2015-04, Vol.38 (4), p.383-393

2015

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Mesenchymal precursor cells maintain the differentiation and proliferation potentials of breast epithelial cells

Breast cancer research : BCR, 2014-06, Vol.16 (3), p.R60-R60, Article R60

2014

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‘The charmingest place’: non-coding RNA, lineage tracing, tumor heterogeneity, metastasis and metabolism--new methods in mammary gland development and cancer: the fifth ENBDC Workshop

Breast cancer research : BCR, 2013-01, Vol.15 (5), p.313-313, Article 313

2013

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New methods in mammary gland development and cancer: proteomics, epigenetics, symmetric division and metastasis

Breast cancer research : BCR, 2012-07, Vol.14 (4), p.314-314, Article 314

2012

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Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis

Cancer gene therapy, 2000-01, Vol.7 (1), p.20-26

2000

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Can phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibition ERase them all?

Breast cancer research : BCR, 2010-01, Vol.12 (5), p.315-315, Article 315

2010

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Deletion pattern of the STS gene in X-linked ichthyosis in a Mexican population

Molecular medicine (Cambridge, Mass.), 2001-12, Vol.7 (12), p.845-849

2001

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Anti-CCL2: building a reservoir or opening the floodgates to metastasis?

Breast cancer research : BCR, 2015-05, Vol.17 (1), p.68-68, Article 68

2015

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Isolation of a distinct class of gain-of-function SHP-2 mutants with oncogenic RAS-like transforming activity from solid tumors

Oncogene, 2008-06, Vol.27 (25), p.3508-3515

2008

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Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers

Oncogene, 2020-01, Vol.39 (1), p.50-63

2020

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Mechanism-based cancer therapy: resistance to therapy, therapy for resistance

Stops along the RAS pathway in human genetic disease

Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

A role for the scaffolding adapter GAB2 in breast cancer

Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium

NF-κB2/p100 induces Bcl-2 expression

The ninth ENBDC Weggis meeting: growth and in-depth characterisation of normal and neoplastic breast cells

Inhibition of the NF-kappa B transcription factor increases Bax expression in cancer cell lines

Early but not late pregnancy induces lifelong reductions in the proportion of mammary progesterone sensing cells and epithelial Wnt signaling

A high-throughput drug screen reveals means to differentiate triple-negative breast cancer

Complexity galore: 3D cultures, biomechanics and systems medicine at the eighth ENBDC workshop "Methods in Mammary Gland Development and Cancer"

Hippo inactivation feeds tumor-initiating cells

Co-expression of HER2 and HER3 receptor tyrosine kinases enhances invasion of breast cells via stimulation of interleukin-8 autocrine secretion

Assessment of a New Instrument for Detecting Preventable Adverse Drug Reactions

Mesenchymal precursor cells maintain the differentiation and proliferation potentials of breast epithelial cells

‘The charmingest place’: non-coding RNA, lineage tracing, tumor heterogeneity, metastasis and metabolism--new methods in mammary gland development and cancer: the fifth ENBDC Workshop

New methods in mammary gland development and cancer: proteomics, epigenetics, symmetric division and metastasis

Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis

Can phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibition ERase them all?

Deletion pattern of the STS gene in X-linked ichthyosis in a Mexican population

Anti-CCL2: building a reservoir or opening the floodgates to metastasis?

Isolation of a distinct class of gain-of-function SHP-2 mutants with oncogenic RAS-like transforming activity from solid tumors

Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers

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