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Total Synthesis of Vinblastine, Related Natural Products, and Key Analogues and Development of Inspired Methodology Suitable for the Systematic Study of Their Structure–Function Properties

Accounts of chemical research, 2015-03, Vol.48 (3), p.653-662

2015

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Completion of the canonical pathway for assembly of anticancer drugs vincristine/vinblastine in Catharanthus roseus

The Plant journal : for cell and molecular biology, 2019-01, Vol.97 (2), p.257-266

2019

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Randomized Phase III Trial of Dose-dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin, or Gemcitabine and Cisplatin as Perioperative Chemotherapy for Patients with Muscle-invasive Bladder Cancer. Analysis of the GETUG/AFU V05 VESPER Trial Secondary Endpoints: Chemotherapy Toxicity and Pathological Responses

European urology, 2021-02, Vol.79 (2), p.214-221

2021

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Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues

Journal of the American Chemical Society, 2009-04, Vol.131 (13), p.4904-4916

2009

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Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label, phase 3 study

The lancet oncology, 2018-01, Vol.19 (1), p.139-148

2018

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Phase I Study of Veliparib (ABT-888) Combined with Cisplatin and Vinorelbine in Advanced Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer

Clinical cancer research, 2016-06, Vol.22 (12), p.2855-2864

2016

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Asymmetric Total Synthesis of Vindorosine, Vindoline, and Key Vinblastine Analogues

Journal of the American Chemical Society, 2010-09, Vol.132 (38), p.13533-13544

2010

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An Endophytic Fungus, Talaromyces radicus, Isolated from Catharanthus roseus, Produces Vincristine and Vinblastine, Which Induce Apoptotic Cell Death

PloS one, 2015-12, Vol.10 (12), p.e0144476-e0144476

2015

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Phase III Randomized Study Comparing Docetaxel Plus Trastuzumab With Vinorelbine Plus Trastuzumab As First-Line Therapy of Metastatic or Locally Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: The HERNATA Study

Journal of clinical oncology, 2011-01, Vol.29 (3), p.264-271

2011

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Ultrapotent vinblastines in which added molecular complexity further disrupts the target tubulin dimer–dimer interface

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (35), p.9691-9698

2016

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Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up

Annals of oncology, 2019-06, Vol.30 (6), p.970-976

2019

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Peptide-conjugated nanoparticles for targeted imaging and therapy of prostate cancer

Biomaterials, 2016-08, Vol.99, p.1-15

2016

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Safety and efficacy of neratinib (HKI-272) plus vinorelbine in the treatment of patients with ErbB2-positive metastatic breast cancer pretreated with anti-HER2 therapy

Annals of oncology, 2013-01, Vol.24 (1), p.109-116

2013

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Total Synthesis of (−)-Vindoline and (+)-4-epi-Vindoline Based on a 1,3,4-Oxadiazole Tandem Intramolecular [4 + 2]/[3 + 2] Cycloaddition Cascade Initiated by an Allene Dienophile

Organic letters, 2015-11, Vol.17 (21), p.5460-5463

2015

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Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma

The New England journal of medicine, 2017-03, Vol.376 (11), p.1015-1026

2017

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Iron(III)/NaBH4-Mediated Additions to Unactivated Alkenes: Synthesis of Novel 20′-Vinblastine Analogues

Organic letters, 2012-03, Vol.14 (6), p.1428-1431

2012

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ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's Lymphoma

The New England journal of medicine, 2012-02, Vol.366 (5), p.399-408

2012

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Isolation, purification and characterization of vinblastine and vincristine from endophytic fungus Fusarium oxysporum isolated from Catharanthus roseus

PloS one, 2013-09, Vol.8 (9), p.e71805-e71805

2013

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Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin’s Lymphoma

The New England journal of medicine, 2016-06, Vol.374 (25), p.2419-2429

2016

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ABVD versus BEACOPP for Hodgkin's Lymphoma When High-Dose Salvage Is Planned

The New England journal of medicine, 2011-07, Vol.365 (3), p.203-212

2011

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Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin’s Lymphoma

The New England journal of medicine, 2018-01, Vol.378 (4), p.331-344

2018

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Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial

The Lancet (British edition), 2009-05, Vol.373 (9674), p.1525-1531

2009

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Phase III Trial of Four Cisplatin-Containing Doublet Combinations in Stage IVB, Recurrent, or Persistent Cervical Carcinoma: A Gynecologic Oncology Group Study

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4649-4655

2009

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