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Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells

Journal of Ginseng Research, 2023, 47(4), , pp.572-582

2023

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Protopanaxadiol derivative: A plant origin of novel selective glucocorticoid receptor modulator with anti-inflammatory effect

European journal of pharmacology, 2024-11, Vol.983, p.176901, Article 176901

2024

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Optimization of a cytochrome P450 oxidation system for enhancing protopanaxadiol production in Saccharomyces cerevisiae

Biotechnology and bioengineering, 2016-08, Vol.113 (8), p.1787-1795

2016

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Protopanaxadiol alleviates neuropathic pain by spinal microglial dynorphin A expression following glucocorticoid receptor activation

British journal of pharmacology, 2021-08, Vol.178 (15), p.2976-2997

2021

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Protopanaxadiol improves lupus nephritis by regulating the PTX3/MAPK/ERK1/2 pathway

Journal of natural medicines, 2024-06, Vol.78 (3), p.474-487

2024

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Antidepressant‐like effects of 20(S)‐protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms

Phytotherapy research, 2019-10, Vol.33 (10), p.2726-2736

2019

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Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats

Behavioural brain research, 2020-09, Vol.393, p.112710, Article 112710

2020

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Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats

Neuroscience letters, 2023-09, Vol.814, p.137439-137439, Article 137439

2023

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Biotransformation of Protopanaxadiol-Type Ginsenosides in Korean Ginseng Extract into Food-Available Compound K by an Extracellular Enzyme from Aspergillus niger

Journal of microbiology and biotechnology, 2020-10, Vol.30 (10), p.1560

2020

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Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides

Metabolic engineering, 2013-11, Vol.20, p.146-156

2013

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Polycaprolactone nanofibres loaded with 20(S)-protopanaxadiol for in vitro and in vivo anti-tumour activity study

Royal Society open science, 2018-05, Vol.5 (5), p.180137-180137

2018

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Protopanaxadiol alleviates obesity in high-fat diet-fed mice via activation of energy-sensing neuron in the paraventricular nucleus of hypothalamus

Biochemical and biophysical research communications, 2019-06, Vol.513 (4), p.1092-1099

2019

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Identification, 3D modelling, and expression analysis of protopanaxadiol and protopanaxatriol synthases in Vietnamese ginseng under vanadium elicitation

The journal of horticultural science & biotechnology, 2024-01, Vol.ahead-of-print (ahead-of-print), p.1-11

2024

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Metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy

Pharmacological research, 2021-08, Vol.170, p.105728-105728, Article 105728

2021

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Increased Production of Ginsenoside Compound K by Optimizing the Feeding of American Ginseng Extract during Fermentation by Aspergillus tubingensis

Journal of microbiology and biotechnology, 2022-07, Vol.32 (7), p.902-910

2022

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The protective effect of 20(S)-protopanaxadiol (PPD) against chronic sleep deprivation (CSD)-induced memory impairments in mice

Brain research bulletin, 2018-03, Vol.137, p.249-256

2018

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20(S)‐Protopanaxadiol inhibits epithelial‐mesenchymal transition by promoting retinoid X receptor alpha in human colorectal carcinoma cells

Journal of cellular and molecular medicine, 2020-12, Vol.24 (24), p.14349-14365

2020

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Non-clinical pharmacokinetic behavior of ginsenosides

Journal of Ginseng Research, 2019, 43(3), , pp.354-360

2019

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Protective Effect of 20(S)-Protopanaxadiol on D‑Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase

Journal of agricultural and food chemistry, 2023-02, Vol.71 (7), p.3484-3496

2023

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Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification

European journal of medicinal chemistry, 2020-03, Vol.189, p.112087-112087, Article 112087

2020

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Comparative analysis of ginsenosides in human glucocorticoid receptor binding, transactivation, and transrepression

European journal of pharmacology, 2017-11, Vol.815, p.501-511

2017

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Ginsenosides: the need to move forward from bench to clinical trials

Journal of Ginseng Research, 2019, 43(3), , pp.361-367

2019

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Complete Biotransformation of Protopanaxadiol-Type Ginsenosides to 20‑O‑β-Glucopyranosyl-20(S)‑protopanaxadiol Using a Novel and Thermostable β‑Glucosidase

Journal of agricultural and food chemistry, 2018-03, Vol.66 (11), p.2822-2829

2018

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Preparation of minor ginsenosides C-K and C-Mx from protopanaxadiol ginsenosides of American ginseng leaves by a enzyme from Aspergillus sp.agl-84 strain

Process biochemistry (1991), 2021-04, Vol.103, p.50-59

2021

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Pharmacokinetic interaction of calcitriol with 20(S)-protopanaxadiol in mice: Determined by LC/MS analysis

European journal of pharmaceutical sciences, 2019-03, Vol.130, p.173-180

2019

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Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells

Protopanaxadiol derivative: A plant origin of novel selective glucocorticoid receptor modulator with anti-inflammatory effect

Optimization of a cytochrome P450 oxidation system for enhancing protopanaxadiol production in Saccharomyces cerevisiae

Protopanaxadiol alleviates neuropathic pain by spinal microglial dynorphin A expression following glucocorticoid receptor activation

Protopanaxadiol improves lupus nephritis by regulating the PTX3/MAPK/ERK1/2 pathway

Antidepressant‐like effects of 20(S)‐protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms

Ginsenoside 20(S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats

Neuroprotective effect of 20 (S) - Protopanaxadiol (PPD) attenuates NLRP3 inflammasome-mediated microglial pyroptosis in vascular dementia rats

Biotransformation of Protopanaxadiol-Type Ginsenosides in Korean Ginseng Extract into Food-Available Compound K by an Extracellular Enzyme from Aspergillus niger

Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides

Polycaprolactone nanofibres loaded with 20(S)-protopanaxadiol for in vitro and in vivo anti-tumour activity study

Protopanaxadiol alleviates obesity in high-fat diet-fed mice via activation of energy-sensing neuron in the paraventricular nucleus of hypothalamus

Identification, 3D modelling, and expression analysis of protopanaxadiol and protopanaxatriol synthases in Vietnamese ginseng under vanadium elicitation

Metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy

Increased Production of Ginsenoside Compound K by Optimizing the Feeding of American Ginseng Extract during Fermentation by Aspergillus tubingensis

The protective effect of 20(S)-protopanaxadiol (PPD) against chronic sleep deprivation (CSD)-induced memory impairments in mice

20(S)‐Protopanaxadiol inhibits epithelial‐mesenchymal transition by promoting retinoid X receptor alpha in human colorectal carcinoma cells

Non-clinical pharmacokinetic behavior of ginsenosides

Protective Effect of 20(S)-Protopanaxadiol on D‑Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase

Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification

Comparative analysis of ginsenosides in human glucocorticoid receptor binding, transactivation, and transrepression

Ginsenosides: the need to move forward from bench to clinical trials

Complete Biotransformation of Protopanaxadiol-Type Ginsenosides to 20‑O‑β-Glucopyranosyl-20(S)‑protopanaxadiol Using a Novel and Thermostable β‑Glucosidase

Preparation of minor ginsenosides C-K and C-Mx from protopanaxadiol ginsenosides of American ginseng leaves by a enzyme from Aspergillus sp.agl-84 strain

Pharmacokinetic interaction of calcitriol with 20(S)-protopanaxadiol in mice: Determined by LC/MS analysis

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