UB Paderborn / Katalog / Suche / in CDI

Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist gegebenenfalls nur via VPN oder Shibboleth (DFN-AAI) möglich. mehr Informationen...

1 – 25 von 97.976

Sortiert nach

Targeting SARS‐CoV‐2 viral proteases as a therapeutic strategy to treat COVID‐19

Journal of medical virology, 2021-05, Vol.93 (5), p.2722-2734

2021

Volltextzugriff (PDF)

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1

2021

Volltextzugriff (PDF)

From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design

The FEBS journal, 2014-09, Vol.281 (18), p.4085-4096

Hilgenfeld, Rolf

2014

Volltextzugriff (PDF)

Identification of potential plant-based inhibitor against viral proteases of SARS-CoV-2 through molecular docking, MM-PBSA binding energy calculations and molecular dynamics simulation

Molecular diversity, 2021-08, Vol.25 (3), p.1963-1977

2021

Volltextzugriff (PDF)

Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors

Angewandte Chemie (International ed.), 2021-04, Vol.60 (18), p.10423-10429

International ed. in English, 2021

Volltextzugriff (PDF)

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

Science (American Association for the Advancement of Science), 2020-04, Vol.368 (6489), p.409-412

2020

Volltextzugriff (PDF)

Exploring the Binding Mechanism of PF-07321332 SARS-CoV-2 Protease Inhibitor through Molecular Dynamics and Binding Free Energy Simulations

International journal of molecular sciences, 2021-08, Vol.22 (17), p.9124

2021

Volltextzugriff (PDF)

Abstract 1734 Investigating the catalytic activity of PRSS23 as a novel serine protease in ovarian cancer

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106189, Article 106189

2024

Volltextzugriff (PDF)

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12725-12747

2020

Volltextzugriff (PDF)

Potential Resistance of SARS-CoV-2 Main Protease (Mpro) against Protease Inhibitors: Lessons Learned from HIV-1 Protease

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3507

2022

Volltextzugriff (PDF)

A Dual‐Color Fluorescent Probe Allows Simultaneous Imaging of Main and Papain‐like Proteases of SARS‐CoV‐2‐Infected Cells for Accurate Detection and Rapid Inhibitor Screening

Angewandte Chemie (International ed.), 2022-02, Vol.61 (9), p.e202113617-n/a

International ed. in English, 2022

Volltextzugriff (PDF)

GC-MS, LC-MS/MS, Docking and Molecular Dynamics Approaches to Identify Potential SARS-CoV-2 3-Chymotrypsin-Like Protease Inhibitors from Zingiber officinale Roscoe

Molecules (Basel, Switzerland), 2021-08, Vol.26 (17), p.5230

2021

Volltextzugriff (PDF)

X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease

Science (American Association for the Advancement of Science), 2021-05, Vol.372 (6542), p.642-646

2021

Volltextzugriff (PDF)

Diversity, molecular mechanisms and structure-activity relationships of marine protease inhibitors—A review

Pharmacological research, 2021-04, Vol.166, p.105521, Article 105521

2021

Volltextzugriff (PDF)

SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome

Molecules (Basel, Switzerland), 2021-03, Vol.26 (5), p.1409

2021

Volltextzugriff (PDF)

Mass Spectrometric Assays Reveal Discrepancies in Inhibition Profiles for the SARS‐CoV‐2 Papain‐Like Protease

ChemMedChem, 2022-05, Vol.17 (9), p.e202200016-n/a

2022

Volltextzugriff (PDF)

Inhibition Mechanism of SARS‐CoV‐2 Main Protease with Ketone‐Based Inhibitors Unveiled by Multiscale Simulations: Insights for Improved Designs

Angewandte Chemie (International ed.), 2021-12, Vol.60 (49), p.25933-25941

International ed. in English, 2021

Volltextzugriff (PDF)

Structure-Based Virtual Screening to Discover Potential Lead Molecules for the SARS-CoV‑2 Main Protease

Journal of chemical information and modeling, 2020-12, Vol.60 (12), p.5781-5793

2020

Volltextzugriff (PDF)

Improved SARS-CoV-2 main protease high-throughput screening assay using a 5-carboxyfluorescein substrate

The Journal of biological chemistry, 2022-04, Vol.298 (4), p.101739-101739, Article 101739

2022

Volltextzugriff (PDF)

In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT Studies

Molecules (Basel, Switzerland), 2021-10, Vol.26 (21), p.6593

2021

Volltextzugriff (PDF)

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

Nature communications, 2022-04, Vol.13 (1), p.1891-1891, Article 1891

2022

Volltextzugriff (PDF)

In silico evaluation of atazanavir as a potential HIV main protease inhibitor and its comparison with new designed analogs

Computers in biology and medicine, 2022-06, Vol.145, p.105523-105523, Article 105523

2022

Volltextzugriff (PDF)

Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19

Nature communications, 2021-10, Vol.12 (1), p.6055-17, Article 6055

2021

Volltextzugriff (PDF)

A computational evaluation of targeted oxidation strategy (TOS) for potential inhibition of SARS-CoV-2 by disulfiram and analogues

Biophysical chemistry, 2021-09, Vol.276, p.106610-106610, Article 106610

2021

Volltextzugriff (PDF)

1 – 25 von 97.976

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(87.215)
Mit Volltextzugriff
(83.861)

Publikationsform

8 weitere anzeigen...

Weniger anzeigen...

Sprache

Englisch
(94.434)
Japanisch
(16.174)
Russisch
(881)
Deutsch
(645)
Portugiesisch
(486)
Spanisch
(454)
Französisch
(453)
Chinesisch
(255)
Koreanisch
(195)
Polnisch
(102)
Italienisch
(77)
Tschechisch
(37)
Norwegisch
(31)
Ukrainisch
(23)
Niederländisch
(22)
Slowakisch
(22)
Ungarisch
(20)
Croatian
(19)
Dänisch
(17)
Türkisch
(13)

15 weitere anzeigen...

Weniger anzeigen...

Erscheinungsjahr

n.n

n.n

Thema

Science & Technology
(76.472)
Life Sciences & Biomedicine
(68.637)
Humans
(42.403)
Animals
(28.722)
Biochemistry & Molecular Biology
(21.203)
Biological And Medical Sciences
(20.885)
Proteases
(18.214)
Protease
(18.203)
Male
(14.363)
Protease Inhibitors
(14.033)
Proteins
(12.619)
Female
(12.468)
Protease Inhibitors - Pharmacology
(12.360)
Fundamental And Applied Biological Sciences. Psychology
(11.421)
Medical Sciences
(10.925)
Pharmacology & Pharmacy
(10.098)
Chemistry
(9.333)
Physical Sciences
(9.080)
Amino Acid Sequence
(8.797)
Mice
(8.358)

15 weitere anzeigen...

Weniger anzeigen...

Kollektion

MEDLINE
(72.626)
Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
(46.420)
IngentaConnect
(44.185)
Journals@Ovid Ovid Full Text
(27.250)
Access via ScienceDirect (Elsevier)
(19.549)
IngentaConnect Journals
(19.349)
EZB-NALI5-00465 Elsevier Archive NL
(17.007)
Single Journals
(14.777)
Access via Wiley Online Library
(13.465)
SpringerNature Journals
(10.544)
Wiley Online Library Full Collection 2018
(10.421)
SpringerLINK Contemporary (Konsortium Baden-Württemberg)
(6.740)
Access via Oxford University Press
(4.244)
Access via Taylor & Francis
(3.663)
Taylor & Francis Current Content Access
(3.370)
JSTOR
(3.255)
Taylor & Francis:Master (3349 titles)
(3.168)
Nexis Uni
(2.860)
Nature
(2.493)
Oxford Journals 2020 Medicine
(1.961)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

Plos One
(2.511)
The Journal Of Biological Chemistry
(2.150)
Proceedings Of The National Academy Of Sciences - Pnas
(1.177)
Aids
(1.061)
Febs Letters
(885)
Biochemical And Biophysical Research Communications
(880)
Bioorganic & Medicinal Chemistry Letters
(872)
International Journal Of Molecular Sciences
(780)
Biochimica Et Biophysica Acta
(768)
Biochemistry
(628)

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt