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The inhibitory cytokine IL-35 contributes to regulatory T-cell function

Nature, 2007-11, Vol.450 (7169), p.566-569

2007

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Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice

Gastroenterology (New York, N.Y. 1943), 2018-02, Vol.154 (3), p.675-688

2018

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Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

Cancer cell, 2014-11, Vol.26 (5), p.623-637

2014

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IL-12 Produced by Dendritic Cells Augments CD8+ T Cell Activation through the Production of the Chemokines CCL1 and CCL17

The Journal of immunology (1950), 2008-12, Vol.181 (12), p.8576-8584

2008

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The expanding repertoire of the IL-12 cytokine family in teleost fish: Identification of three paralogues each of the p35 and p40 genes in salmonids, and comparative analysis of their expression and modulation in Atlantic salmon Salmo salar

Developmental and comparative immunology, 2014-10, Vol.46 (2), p.194-207

2014

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Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers

Nature medicine, 2016-06, Vol.22 (6), p.679-684

2016

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Interleukin-12p35 knockout promotes macrophage differentiation, aggravates vascular dysfunction, and elevates blood pressure in angiotensin II-infused mice

Cardiovascular research, 2019-05, Vol.115 (6), p.1102-1113

2019

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Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

Cell host & microbe, 2014-04, Vol.15 (4), p.494-505

2014

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Neutrophil functions can be regulated by IL-35, which is mainly expressed in IL-15Rα+ cells in grass carp (Ctenopharyngodon idella)

Developmental and comparative immunology, 2021-08, Vol.121, p.104103-104103, Article 104103

2021

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Role of the IL-12/IL-35 balance in patients with Sjögren syndrome

Journal of allergy and clinical immunology, 2018-07, Vol.142 (1), p.258-268.e5

2018

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Teprotumumab Divergently Alters Fibrocyte Gene Expression: Implications for Thyroid-associated Ophthalmopathy

The journal of clinical endocrinology and metabolism, 2022-09, Vol.107 (10), p.e4037-e4047

2022

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MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression

The Journal of immunology (1950), 2009-04, Vol.182 (8), p.4994-5002

2009

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Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

The Journal of experimental medicine, 2009-02, Vol.206 (2), p.299-311

2009

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Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance

Cell reports (Cambridge), 2020-01, Vol.30 (4), p.1039-1051.e5

2020

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Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer

British journal of cancer, 2019-04, Vol.120 (9), p.903-912

2019

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IFN-beta inhibits human Th17 cell differentiation

The Journal of immunology (1950), 2009-10, Vol.183 (8), p.5418-5427

2009

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The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production

The Journal of biological chemistry, 2013-03, Vol.288 (9), p.6763-6776

2013

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Targeted Reconstitution of Cytokine Activity upon Antigen Binding using Split Cytokine Antibody Fusion Proteins

The Journal of biological chemistry, 2016-08, Vol.291 (35), p.18139-18147

2016

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Ibudilast Inhibits Chemokine Expression in Rheumatoid Arthritis Synovial Fibroblasts and Exhibits Immunomodulatory Activity in Experimental Arthritis

Arthritis & rheumatology (Hoboken, N.J.), 2019-05, Vol.71 (5), p.703-711

2019

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Role of Interleukin-12 in Protection against Pulmonary Infection with Methicillin-Resistant Staphylococcus aureus

Antimicrobial agents and chemotherapy, 2015-10, Vol.59 (10), p.6308-6316

2015

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IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection

The Journal of immunology (1950), 2015-04, Vol.194 (8), p.3861-3872

2015

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T Follicular Helper Cell Differentiation, Function, and Roles in Disease

Immunity (Cambridge, Mass.), 2014-10, Vol.41 (4), p.529-542

Crotty, Shane

2014

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Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

The Journal of experimental medicine, 2008-04, Vol.205 (4), p.799-810

2008

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Interleukin‐35 in immune‐related diseases: protection or destruction

Immunology, 2019-05, Vol.157 (1), p.13-20

2019

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IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis

The Journal of experimental medicine, 2006-10, Vol.203 (11), p.2485-2494

2006

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The inhibitory cytokine IL-35 contributes to regulatory T-cell function

Interleukin 35 Expression Correlates With Microvessel Density in Pancreatic Ductal Adenocarcinoma, Recruits Monocytes, and Promotes Growth and Angiogenesis of Xenograft Tumors in Mice

Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells

IL-12 Produced by Dendritic Cells Augments CD8+ T Cell Activation through the Production of the Chemokines CCL1 and CCL17

The expanding repertoire of the IL-12 cytokine family in teleost fish: Identification of three paralogues each of the p35 and p40 genes in salmonids, and comparative analysis of their expression and modulation in Atlantic salmon Salmo salar

Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers

Interleukin-12p35 knockout promotes macrophage differentiation, aggravates vascular dysfunction, and elevates blood pressure in angiotensin II-infused mice

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

Neutrophil functions can be regulated by IL-35, which is mainly expressed in IL-15Rα+ cells in grass carp (Ctenopharyngodon idella)

Role of the IL-12/IL-35 balance in patients with Sjögren syndrome

Teprotumumab Divergently Alters Fibrocyte Gene Expression: Implications for Thyroid-associated Ophthalmopathy

MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance

Increased expression of the immunosuppressive interleukin-35 in patients with non-small cell lung cancer

IFN-beta inhibits human Th17 cell differentiation

The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production

Targeted Reconstitution of Cytokine Activity upon Antigen Binding using Split Cytokine Antibody Fusion Proteins

Ibudilast Inhibits Chemokine Expression in Rheumatoid Arthritis Synovial Fibroblasts and Exhibits Immunomodulatory Activity in Experimental Arthritis

Role of Interleukin-12 in Protection against Pulmonary Infection with Methicillin-Resistant Staphylococcus aureus

IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

Interleukin‐35 in immune‐related diseases: protection or destruction

IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis

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