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In vitro and ex vivo experimental models for evaluation of intranasal systemic drug delivery as well as direct nose‐to‐brain drug delivery

Biopharmaceutics & drug disposition, 2023-02, Vol.44 (1), p.94-112

2023

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Stimuli-responsive In situ gelling system for nose-to-brain drug delivery

Journal of controlled release, 2020-11, Vol.327, p.235-265

2020

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Mucoadhesive nanoemulsion enhances brain bioavailability of luteolin after intranasal administration and induces apoptosis to SH-SY5Y neuroblastoma cells

International journal of pharmaceutics, 2022-10, Vol.626, p.122142-122142, Article 122142

2022

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Shortcut Approaches to Substance Delivery into the Brain Based on Intranasal Administration Using Nanodelivery Strategies for Insulin

Molecules (Basel, Switzerland), 2020-11, Vol.25 (21), p.5188

Tashima, Toshihiko

2020

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Nanotechnology for enhanced nose-to-brain drug delivery in treating neurological diseases

Journal of controlled release, 2024-02, Vol.366, p.519-534

2024

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Histopathological evaluation of insulin-DMSO formula designed for direct nose-to-brain delivery

Histology and histopathology, 2022-05, Vol.37 (5), p.431-439

2022

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Multiple CEST contrast imaging of nose-to-brain drug delivery using iohexol liposomes at 3T MRI

Journal of controlled release, 2023-02, Vol.354, p.208-220

2023

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Intranasal Nose-to-Brain Drug Delivery via the Olfactory Region in Mice: Two In-Depth Protocols for Region-Specific Intranasal Application of Antibodies and for Expression Analysis of Fc Receptors via In Situ Hybridization in the Nasal Mucosa

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2754, p.387

2024

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Effective nose-to-brain drug delivery using a combination system targeting the olfactory region in monkeys

Journal of controlled release, 2023-07, Vol.359, p.384-399

2023

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A Recent Update on Intranasal Delivery of High Molecular Weight Proteins, Peptides, and Hormones

Current pharmaceutical design, 2021-01, Vol.27 (42), p.4279

2021

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Smart thermosensitive chitosan hydrogel for nasal delivery of ibuprofen to treat neurological disorders

Expert opinion on drug delivery, 2019-04, Vol.16 (4), p.453-466

2019

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Preparation and evaluation of niosomal chitosan-based in situ gel formulation for direct nose-to-brain methotrexate delivery

International journal of biological macromolecules, 2022-07, Vol.213, p.1115-1126

2022

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A Cell-Based Nasal Model for Screening the Deposition, Biocompatibility, and Transport of Aerosolized PLGA Nanoparticles

Molecular pharmaceutics, 2024-03, Vol.21 (3), p.1108-1124

2024

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Nasal Drug Delivery: Formulations, Developments, Challenges, and Solutions

1, 2023

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Dodecyl creatine ester therapy: from promise to reality

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.186-186, Article 186

2024

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Multifaceted nanolipidic carriers: a modish stratagem accentuating nose-to-brain drug delivery

Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 2023-07, Vol.25 (7), p.150, Article 150

2023

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Nose to brain drug delivery - A promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion

Pharmacological research, 2020-09, Vol.159, p.104795-104795, Article 104795

2020

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Mixed Mucoadhesive Amphiphilic Polymeric Nanoparticles Cross a Model of Nasal Septum Epithelium in Vitro

ACS applied materials & interfaces, 2019-06, Vol.11 (24), p.21360-21371

2019

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Direct nose-to-brain delivery of lamotrigine following intranasal administration to mice

International journal of pharmaceutics, 2015-07, Vol.490 (1-2), p.39-46

2015

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Formulation of olfactory-targeted microparticles with tamarind seed polysaccharide to improve nose-to-brain transport of drugs

Carbohydrate polymers, 2017-05, Vol.163, p.216-226

2017

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Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System

Frontiers in pharmacology, 2022-01, Vol.12, p.789780-789780

2022

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Nose-to-brain drug delivery for the treatment of glioblastoma multiforme: nanotechnological interventions

Pharmaceutical development and technology, 2023-12, Vol.28 (10), p.1032-1047

2023

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Intranasal administration of carbamazepine to mice: A direct delivery pathway for brain targeting

European journal of pharmaceutical sciences, 2014-08, Vol.60, p.32-39

2014

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Exploring Nose to Brain Nano Delivery for Effective Management of Migraine

Current drug delivery, 2023-02, Vol.20 (2), p.144

2023

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Pulsatile Bi-Directional Aerosol Flow Affects Aerosol Delivery to the Intranasal Olfactory Region: A Patient-Specific Computational Study

Frontiers in pharmacology, 2021-11, Vol.12, p.746420-746420

2021

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In vitro and ex vivo experimental models for evaluation of intranasal systemic drug delivery as well as direct nose‐to‐brain drug delivery

Stimuli-responsive In situ gelling system for nose-to-brain drug delivery

Mucoadhesive nanoemulsion enhances brain bioavailability of luteolin after intranasal administration and induces apoptosis to SH-SY5Y neuroblastoma cells

Shortcut Approaches to Substance Delivery into the Brain Based on Intranasal Administration Using Nanodelivery Strategies for Insulin

Nanotechnology for enhanced nose-to-brain drug delivery in treating neurological diseases

Histopathological evaluation of insulin-DMSO formula designed for direct nose-to-brain delivery

Multiple CEST contrast imaging of nose-to-brain drug delivery using iohexol liposomes at 3T MRI

Intranasal Nose-to-Brain Drug Delivery via the Olfactory Region in Mice: Two In-Depth Protocols for Region-Specific Intranasal Application of Antibodies and for Expression Analysis of Fc Receptors via In Situ Hybridization in the Nasal Mucosa

Effective nose-to-brain drug delivery using a combination system targeting the olfactory region in monkeys

A Recent Update on Intranasal Delivery of High Molecular Weight Proteins, Peptides, and Hormones

Smart thermosensitive chitosan hydrogel for nasal delivery of ibuprofen to treat neurological disorders

Preparation and evaluation of niosomal chitosan-based in situ gel formulation for direct nose-to-brain methotrexate delivery

A Cell-Based Nasal Model for Screening the Deposition, Biocompatibility, and Transport of Aerosolized PLGA Nanoparticles

Nasal Drug Delivery: Formulations, Developments, Challenges, and Solutions

Dodecyl creatine ester therapy: from promise to reality

Multifaceted nanolipidic carriers: a modish stratagem accentuating nose-to-brain drug delivery

Nose to brain drug delivery - A promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion

Mixed Mucoadhesive Amphiphilic Polymeric Nanoparticles Cross a Model of Nasal Septum Epithelium in Vitro

Direct nose-to-brain delivery of lamotrigine following intranasal administration to mice

Formulation of olfactory-targeted microparticles with tamarind seed polysaccharide to improve nose-to-brain transport of drugs

Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System

Nose-to-brain drug delivery for the treatment of glioblastoma multiforme: nanotechnological interventions

Intranasal administration of carbamazepine to mice: A direct delivery pathway for brain targeting

Exploring Nose to Brain Nano Delivery for Effective Management of Migraine

Pulsatile Bi-Directional Aerosol Flow Affects Aerosol Delivery to the Intranasal Olfactory Region: A Patient-Specific Computational Study

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