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Epigenetic Contributions to Hormonally-Mediated Sexual Differentiation of the Brain

Journal of neuroendocrinology, 2013-11, Vol.25 (11), p.1133-1140

2013

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Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator

Neuropharmacology, 2020-12, Vol.181, p.108333-108333, Article 108333

2020

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Schwann cell development,maturation and regeneration：a focus on classic and emerging intracellular signaling pathways

Neural regeneration research, 2017-07, Vol.12 (7), p.1013-1023

2017

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Luteal phase sertraline treatment of premenstrual dysphoric disorder (PMDD): Effects on markers of hypothalamic pituitary adrenal (HPA) axis activation and inflammation

Psychoneuroendocrinology, 2024-11, Vol.169, p.107145, Article 107145

2024

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Expanding the therapeutic potential of neuro(active)steroids: a promising strategy for hyperdopaminergic behavioral phenotypes

Neuroscience and biobehavioral reviews, 2024-09, Vol.164, p.105842, Article 105842

2024

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GABAkines – Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors

Pharmacology & therapeutics (Oxford), 2022-06, Vol.234, p.108035-108035, Article 108035

2022

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Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

The Journal of biological chemistry, 2019-08, Vol.294 (32), p.12220-12230

2019

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17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3/acetylcholine nicotinic receptor heteromer in dopaminergic neurons

European journal of pharmacology, 2024-08, Vol.976, p.176678, Article 176678

2024

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The role of allopregnanolone in depression and anxiety

Progress in neurobiology, 2014-02, Vol.113, p.79-87

2014

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Towards understanding the biology of premenstrual dysphoric disorder: From genes to GABA

Neuroscience and biobehavioral reviews, 2023-06, Vol.149, p.105168-105168, Article 105168

2023

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Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind, randomized, placebo-controlled clinical trials in the HUMMINGBIRD clinical program

Journal of affective disorders, 2023-01, Vol.320, p.353-359

2023

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Zuranolone provides a rapid response without chronic dosing: Response to correspondence by ten Doesschate et al

Journal of affective disorders, 2022-03, Vol.301, p.445-447

2022

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Are neuroactive steroids promising therapeutic agents in the management of acute and chronic pain?

Psychoneuroendocrinology, 2009-12, Vol.34, p.S178-S185

2009

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Development of neuroactive steroids for the treatment of postpartum depression

Journal of neuroendocrinology, 2022-02, Vol.34 (2), p.e13019-n/a

2022

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Allopregnanolone: An overview on its synthesis and effects

Journal of neuroendocrinology, 2022-02, Vol.34 (2), p.e12996-n/a

2022

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Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression

Psychoneuroendocrinology, 2016-08, Vol.70, p.98-107

2016

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Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid

British journal of anaesthesia : BJA, 2023-02, Vol.130 (2), p.154-164

2023

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Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition

Psychoneuroendocrinology, 2019-01, Vol.99, p.206-215

2019

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Neuroactive steroids and Parkinson's disease

Current opinion in endocrine and metabolic research, 2022-02, Vol.22, p.100312, Article 100312

2022

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Open‐label, proof‐of‐concept study of brexanolone in the treatment of severe postpartum depression

Human psychopharmacology, 2017-03, Vol.32 (2), p.e2576-n/a

2017

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Endogenous Oestradiol Regulates Progesterone Receptor Expression in the Brain of Female Rat Fetuses: What is the Source of Oestradiol?

Journal of neuroendocrinology, 2008-03, Vol.20 (3), p.359-365

2008

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Neuroactive steroid regulation of neurotransmitter release in the CNS: action, mechanism and possible significance

Progress in neurobiology, 2009-10, Vol.89 (2), p.134-152

Zheng, Ping

2009

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Sex, stress and steroids

The European journal of neuroscience, 2020-07, Vol.52 (1), p.2487-2515

2020

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Allopregnanolone: state of the art

Progress in neurobiology, 2014-02, Vol.113, p.1-5

2014

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Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.36-36, Article 36

2024

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Epigenetic Contributions to Hormonally-Mediated Sexual Differentiation of the Brain

Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator

Schwann cell development,maturation and regeneration：a focus on classic and emerging intracellular signaling pathways

Luteal phase sertraline treatment of premenstrual dysphoric disorder (PMDD): Effects on markers of hypothalamic pituitary adrenal (HPA) axis activation and inflammation

Expanding the therapeutic potential of neuro(active)steroids: a promising strategy for hyperdopaminergic behavioral phenotypes

GABAkines – Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors

Metabotropic, but not allosteric, effects of neurosteroids on GABAergic inhibition depend on the phosphorylation of GABAA receptors

17-β-estradiol potentiates the neurotrophic and neuroprotective effects mediated by the dopamine D3/acetylcholine nicotinic receptor heteromer in dopaminergic neurons

The role of allopregnanolone in depression and anxiety

Towards understanding the biology of premenstrual dysphoric disorder: From genes to GABA

Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind, randomized, placebo-controlled clinical trials in the HUMMINGBIRD clinical program

Zuranolone provides a rapid response without chronic dosing: Response to correspondence by ten Doesschate et al

Are neuroactive steroids promising therapeutic agents in the management of acute and chronic pain?

Development of neuroactive steroids for the treatment of postpartum depression

Allopregnanolone: An overview on its synthesis and effects

Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression

Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid

Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition

Neuroactive steroids and Parkinson's disease

Open‐label, proof‐of‐concept study of brexanolone in the treatment of severe postpartum depression

Endogenous Oestradiol Regulates Progesterone Receptor Expression in the Brain of Female Rat Fetuses: What is the Source of Oestradiol?

Neuroactive steroid regulation of neurotransmitter release in the CNS: action, mechanism and possible significance

Sex, stress and steroids

Allopregnanolone: state of the art

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids

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