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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases

Rustum, Youcef M

2019

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Expression of ER-resident selenoproteins and activation of cancer cells apoptosis mechanisms under ER-stress conditions caused by methylseleninic acid

Gene, 2020-09, Vol.755, p.144884, Article 144884

2020

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Methylseleninic acid overcomes gefitinib resistance through asparagine-MET-TOPK signaling axis in non-small cell lung cancer cells

Biochemical pharmacology, 2023-09, Vol.215, p.115690-115690, Article 115690

2023

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Rapid analysis of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) isotopologues in stable isotope-resolved metabolomics (SIRM) using direct infusion nanoelectrospray ultra-high-resolution Fourier transform mass spectrometry (DI-nESI-UHR-FTMS)

Analytica chimica acta, 2021-10, Vol.1181, p.338873-338873, Article 338873

2021

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Redox regulation of protein kinase C by selenometabolites and selenoprotein thioredoxin reductase limits cancer prevention by selenium

Free radical biology & medicine, 2018-11, Vol.127, p.55-61

2018

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THE MAIN CYTOTOXIC EFFECTS OF METHYLSELENINIC ACID ON VARIOUS CANCER CELLS

International journal of molecular sciences, 2021-06, Vol.22 (12), p.6614

2021

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Immunomodulatory and Anti-Inflammatory Properties of Selenium-Containing Agents: Their Role in the Regulation of Defense Mechanisms against COVID-19

International journal of molecular sciences, 2022-02, Vol.23 (4), p.2360

2022

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Inhibitory Effect of Selenium on Esophagus Cancer Cells and the Related Mechanism

Journal of Nutritional Science and Vitaminology, 2020/10/31, Vol.66(5), pp.456-461

2020

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Effect of organo-selenium anticancer drugs on nitrite induced methemoglobinemia: A spectroscopic study

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021-01, Vol.245, p.118946, Article 118946

2021

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Methylseleninic Acid Prevents Patulin-Induced Hepatotoxicity and Nephrotoxicity via the Inhibition of Oxidative Stress and Inactivation of p53 and MAPKs

Journal of agricultural and food chemistry, 2017-07, Vol.65 (26), p.5299-5305

2017

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Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells

Oncotarget, 2018-01, Vol.9 (3), p.3014-3028

2018

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Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS‐mediated mitochondrial pathway

Journal of biochemical and molecular toxicology, 2023-08, Vol.37 (8), p.e23387-n/a

2023

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The potential effect of methylseleninic acid (MSA) against γ-irradiation induced testicular damage in rats: Impact on JAK/STAT pathway

Archives of biochemistry and biophysics, 2020-01, Vol.679, p.108205, Article 108205

2020

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Response surface methodology optimizes selenium inhibition of prostate cancer PC-3 cell viability

Journal of trace elements in medicine and biology, 2024-07, Vol.84, p.127414-127414, Article 127414

2024

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Methylselenol Produced In Vivo from Methylseleninic Acid or Dimethyl Diselenide Induces Toxic Protein Aggregation in Saccharomyces cerevisiae

International journal of molecular sciences, 2021-02, Vol.22 (5), p.2241

2021

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Modulation of MHC class I surface expression in B16F10 melanoma cells by methylseleninic acid

Oncoimmunology, 2017-06, Vol.6 (6), p.e1259049-e1259049

2017

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Methylseleninic Acid Sensitizes Ovarian Cancer Cells to T-Cell Mediated Killing by Decreasing PDL1 and VEGF Levels

Frontiers in oncology, 2018-09, Vol.8, p.407

2018

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Methylseleninic acid overcomes programmed death‐ligand 1‐mediated resistance of prostate cancer and lung cancer

Molecular carcinogenesis, 2021-11, Vol.60 (11), p.746-757

2021

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Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Pharmacological research, 2015-12, Vol.102, p.218-234

2015

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Methylseleninic acid inhibits human glioma growth in vitro and in vivo by triggering ROS-dependent oxidative damage and apoptosis

Metabolic brain disease, 2024-04, Vol.39 (4), p.625-633

2024

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The Role of Selenoproteins SELENOM and SELENOT in the Regulation of Apoptosis, ER Stress, and Calcium Homeostasis in the A-172 Human Glioblastoma Cell Line

Biology (Basel, Switzerland), 2022-05, Vol.11 (6), p.811

2022

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Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells

International journal of molecular sciences, 2019-01, Vol.20 (1), p.225

2019

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Synergistic Induction of Apoptosis by Methylseleninic Acid and Cisplatin, The Role of ROS-ERK/AKT-p53 Pathway

Molecular pharmaceutics, 2014-04, Vol.11 (4), p.1282-1293

2014

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Selective Impact of Selenium Compounds on Two Cytokine Storm Players

Journal of personalized medicine, 2023-09, Vol.13 (10), p.1455

2023

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Dietary supplementation with methylseleninic acid, but not selenomethionine, reduces spontaneous metastasis of Lewis lung carcinoma in mice

International journal of cancer, 2012-09, Vol.131 (6), p.1260-1266

2012

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Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases

Expression of ER-resident selenoproteins and activation of cancer cells apoptosis mechanisms under ER-stress conditions caused by methylseleninic acid

Methylseleninic acid overcomes gefitinib resistance through asparagine-MET-TOPK signaling axis in non-small cell lung cancer cells

Rapid analysis of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) isotopologues in stable isotope-resolved metabolomics (SIRM) using direct infusion nanoelectrospray ultra-high-resolution Fourier transform mass spectrometry (DI-nESI-UHR-FTMS)

Redox regulation of protein kinase C by selenometabolites and selenoprotein thioredoxin reductase limits cancer prevention by selenium

THE MAIN CYTOTOXIC EFFECTS OF METHYLSELENINIC ACID ON VARIOUS CANCER CELLS

Immunomodulatory and Anti-Inflammatory Properties of Selenium-Containing Agents: Their Role in the Regulation of Defense Mechanisms against COVID-19

Inhibitory Effect of Selenium on Esophagus Cancer Cells and the Related Mechanism

Effect of organo-selenium anticancer drugs on nitrite induced methemoglobinemia: A spectroscopic study

Methylseleninic Acid Prevents Patulin-Induced Hepatotoxicity and Nephrotoxicity via the Inhibition of Oxidative Stress and Inactivation of p53 and MAPKs

Methylseleninic acid induces NAD(P)H:quinone oxidoreductase-1 expression through activation of NF-E2-related factor 2 in Chang liver cells

Methylseleninic acid induces apoptosis of human bladder cancer cells through the ROS‐mediated mitochondrial pathway

The potential effect of methylseleninic acid (MSA) against γ-irradiation induced testicular damage in rats: Impact on JAK/STAT pathway

Response surface methodology optimizes selenium inhibition of prostate cancer PC-3 cell viability

Methylselenol Produced In Vivo from Methylseleninic Acid or Dimethyl Diselenide Induces Toxic Protein Aggregation in Saccharomyces cerevisiae

Modulation of MHC class I surface expression in B16F10 melanoma cells by methylseleninic acid

Methylseleninic Acid Sensitizes Ovarian Cancer Cells to T-Cell Mediated Killing by Decreasing PDL1 and VEGF Levels

Methylseleninic acid overcomes programmed death‐ligand 1‐mediated resistance of prostate cancer and lung cancer

Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition

Methylseleninic acid inhibits human glioma growth in vitro and in vivo by triggering ROS-dependent oxidative damage and apoptosis

The Role of Selenoproteins SELENOM and SELENOT in the Regulation of Apoptosis, ER Stress, and Calcium Homeostasis in the A-172 Human Glioblastoma Cell Line

Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells

Synergistic Induction of Apoptosis by Methylseleninic Acid and Cisplatin, The Role of ROS-ERK/AKT-p53 Pathway

Selective Impact of Selenium Compounds on Two Cytokine Storm Players

Dietary supplementation with methylseleninic acid, but not selenomethionine, reduces spontaneous metastasis of Lewis lung carcinoma in mice

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