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Autophagy drives fibroblast senescence through MTORC2 regulation

Autophagy, 2020-11, Vol.16 (11), p.2004-2016

2020

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Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102288-102288, Article 102288

2022

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mTOR Signaling in Growth, Metabolism, and Disease

Cell, 2017-03, Vol.168 (6), p.960-976

2017

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Ras functional proximity proteomics establishes mTORC2 as new direct ras effector

Oncotarget, 2019-08, Vol.10 (50), p.5126-5135

2019

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Modulations of the mTORC2–GATA3 axis by an isorhamnetin activated endosomal–lysosomal system of the J774.1 macrophage-like cell line

Journal of Clinical Biochemistry and Nutrition, 2024, pp.24-22

2024

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Efferocytosis induces macrophage proliferation to help resolve tissue injury

Cell metabolism, 2021-12, Vol.33 (12), p.2445-2463.e8

2021

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Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt

Journal of cell science, 2019-04, Vol.132 (7)

2019

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Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis

Journal of biochemistry (Tokyo), 2014-08, Vol.156 (2), p.73-83

2014

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Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle

Cell metabolism, 2020-10, Vol.32 (4), p.629-642.e8

2020

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Growth Factor-Dependent and -Independent Activation of mTORC2

Trends in endocrinology and metabolism, 2020-01, Vol.31 (1), p.13-24

2020

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The biological function of cytoplasm-translocated ENDOG (endonuclease G)

Autophagy, 2024-02, Vol.20 (2), p.445-447

2024

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Uterine Histotroph and Conceptus Development. II. Arginine and Secreted Phosphoprotein 1 Cooperatively Stimulate Migration and Adhesion of Ovine Trophectoderm Cells via Focal Adhesion-MTORC2 Mediated Cytoskeleton Reorganization

Biology of reproduction, 2016-09, Vol.95 (3), p.71-71

2016

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Wnt signaling and cellular metabolism in osteoblasts

Cellular and molecular life sciences : CMLS, 2017-05, Vol.74 (9), p.1649-1657

2017

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The central moTOR of metabolism

Developmental cell, 2022-03, Vol.57 (6), p.691-706

2022

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mTOR in metabolic homeostasis and disease

Experimental cell research, 2024-08, Vol.441 (2), p.114173, Article 114173

2024

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Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation

The Journal of biological chemistry, 2021-10, Vol.297 (4), p.101100-101100, Article 101100

2021

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mTORC1 and mTORC2 as regulators of cell metabolism in immunity

FEBS letters, 2017-10, Vol.591 (19), p.3089-3103

2017

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mTORC2: The other mTOR in autophagy regulation

Aging cell, 2021-08, Vol.20 (8), p.e13431-n/a

2021

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Nutrient sensing of mTORC1 signaling in cancer and aging

Seminars in cancer biology, 2024-11, Vol.106-107, p.1-12

2024

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Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

Biochemical journal, 2012-01, Vol.441 (1), p.1-21

2012

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mTORC1 Signaling: A Double-Edged Sword in Diabetic β Cells

Cell metabolism, 2018-02, Vol.27 (2), p.314-331

2018

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A novel MTORC2-AKT-ROS axis triggers mitofission and mitophagy-associated execution of colorectal cancer cells upon drug-induced activation of mutant KRAS

Autophagy, 2024-06, Vol.20 (6), p.1418-1441

2024

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GCN5L1-mediated acetylation prevents Rictor degradation in cardiac cells after hypoxic stress

Cellular signalling, 2024-04, Vol.116, p.111065-111065, Article 111065

2024

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Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis

American journal of physiology: endocrinology and metabolism, 2023-06, Vol.324 (6), p.E589-E598

2023

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mTOR Cross-Talk in Cancer and Potential for Combination Therapy

Cancers, 2018-01, Vol.10 (1), p.23

2018

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Autophagy drives fibroblast senescence through MTORC2 regulation

Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt

mTOR Signaling in Growth, Metabolism, and Disease

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector

Modulations of the mTORC2–GATA3 axis by an isorhamnetin activated endosomal–lysosomal system of the J774.1 macrophage-like cell line

Efferocytosis induces macrophage proliferation to help resolve tissue injury

Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and Akt

Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle

Growth Factor-Dependent and -Independent Activation of mTORC2

The biological function of cytoplasm-translocated ENDOG (endonuclease G)

Uterine Histotroph and Conceptus Development. II. Arginine and Secreted Phosphoprotein 1 Cooperatively Stimulate Migration and Adhesion of Ovine Trophectoderm Cells via Focal Adhesion-MTORC2 Mediated Cytoskeleton Reorganization

Wnt signaling and cellular metabolism in osteoblasts

The central moTOR of metabolism

mTOR in metabolic homeostasis and disease

Alkaline intracellular pH (pHi) activates AMPK–mTORC2 signaling to promote cell survival during growth factor limitation

mTORC1 and mTORC2 as regulators of cell metabolism in immunity

mTORC2: The other mTOR in autophagy regulation

Nutrient sensing of mTORC1 signaling in cancer and aging

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

mTORC1 Signaling: A Double-Edged Sword in Diabetic β Cells

A novel MTORC2-AKT-ROS axis triggers mitofission and mitophagy-associated execution of colorectal cancer cells upon drug-induced activation of mutant KRAS

GCN5L1-mediated acetylation prevents Rictor degradation in cardiac cells after hypoxic stress

Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis

mTOR Cross-Talk in Cancer and Potential for Combination Therapy

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