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Mammalian lipoxygenases and their biological relevance

Biochimica et biophysica acta, 2015-04, Vol.1851 (4), p.308-330

2015

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Structural considerations on lipoxygenase function, inhibition and crosstalk with nitric oxide pathways

Biochimie, 2020-11, Vol.178, p.170-180

2020

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Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis

Cell chemical biology, 2020-04, Vol.27 (4), p.387-408

2020

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Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (34), p.E4966-E4975

2016

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Exploring the 2'-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

Molecules (Basel, Switzerland), 2021-05, Vol.26 (9), p.2777

2021

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Genome-wide identification of tomato (Solanum lycopersicum L.) lipoxygenases coupled with expression profiles during plant development and in response to methyl-jasmonate and wounding

Journal of plant physiology, 2018-12, Vol.231, p.318-328

2018

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Regioselectivity of an arachidonate 9S-lipoxygenase from Sphingopyxis macrogoltabida that biosynthesizes 9S,15S- and 11S,17S-dihydroxy fatty acids from C20 and C22 polyunsaturated fatty acids

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2022-03, Vol.1867 (3), p.159091, Article 159091

2022

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Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis

Molecular psychiatry, 2021-11, Vol.26 (11), p.6773-6788

2021

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Recombinant Lipoxygenases and Hydroperoxide Lyases for the Synthesis of Green Leaf Volatiles

Journal of agricultural and food chemistry, 2019-12, Vol.67 (49), p.13367-13392

2019

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Lipoxygenases – Structure and reaction mechanism

Phytochemistry (Oxford), 2009-09, Vol.70 (13), p.1504-1510

2009

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Genome-wide identification and classification of Lipoxygenase gene family and their roles in sorghum-aphid interaction

Plant molecular biology, 2021-03, Vol.105 (4-5), p.527-541

2021

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Fragment-based design, docking, synthesis, biological evaluation and structure–activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors

European journal of medicinal chemistry, 2012, Vol.47 (1), p.111-124

2012

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Synthesis of 13R,20-dihydroxy-docosahexaenoic acid by site-directed mutagenesis of lipoxygenase derived from Oscillatoria nigro-viridis PCC 7112

Biochemical and biophysical research communications, 2020-12, Vol.533 (4), p.893-898

2020

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First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis

Arteriosclerosis, thrombosis, and vascular biology, 2017-10, Vol.37 (10), p.1828-1839

2017

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Arabidopsis lipoxygenase 2 is essential for formation of green leaf volatiles and five‐carbon volatiles

FEBS letters, 2016-04, Vol.590 (7), p.1017-1027

2016

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Genome-wide identification, classification and expression of lipoxygenase gene family in pepper

Plant molecular biology, 2018-11, Vol.98 (4-5), p.375-387

2018

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Synthesis, characterization and anti-inflammatory properties of karanjin (Pongamia pinnata seed) and its derivatives

Bioorganic chemistry, 2021-01, Vol.106, p.104471, Article 104471

2021

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Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers

Molecules (Basel, Switzerland), 2021-02, Vol.26 (5), p.1201

2021

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Novel cinnamic acid derivatives as antioxidant and anticancer agents: design, synthesis and modeling studies

Molecules (Basel, Switzerland), 2014-07, Vol.19 (7), p.9655-9674

2014

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Investigating anti-inflammatory actions of marine algal compound against lipoxygenase concentrating on therapeutic applications through computational approach

Journal of biomolecular structure & dynamics, 2024-11, Vol.42 (17), p.9050-9063

2024

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Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity

Bioorganic & medicinal chemistry, 2009-12, Vol.17 (23), p.8073-8085

2009

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Effect of biotic stress on the presence of secondary metabolites in field pea grains

Journal of the science of food and agriculture, 2022-08, Vol.102 (11), p.4942-4948

2022

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Structure and ligand based drug design strategies in the development of novel 5- LOX inhibitors

Current medicinal chemistry, 2012-08, Vol.19 (22), p.3763-3778

2012

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Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease

Chemical reviews, 2011-10, Vol.111 (10), p.5866-5898

2011

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Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts

European journal of medicinal chemistry, 2009-07, Vol.44 (7), p.3020-3026

2009

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Mammalian lipoxygenases and their biological relevance

Structural considerations on lipoxygenase function, inhibition and crosstalk with nitric oxide pathways

Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Exploring the 2'-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

Genome-wide identification of tomato (Solanum lycopersicum L.) lipoxygenases coupled with expression profiles during plant development and in response to methyl-jasmonate and wounding

Regioselectivity of an arachidonate 9S-lipoxygenase from Sphingopyxis macrogoltabida that biosynthesizes 9S,15S- and 11S,17S-dihydroxy fatty acids from C20 and C22 polyunsaturated fatty acids

Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis

Recombinant Lipoxygenases and Hydroperoxide Lyases for the Synthesis of Green Leaf Volatiles

Lipoxygenases – Structure and reaction mechanism

Genome-wide identification and classification of Lipoxygenase gene family and their roles in sorghum-aphid interaction

Fragment-based design, docking, synthesis, biological evaluation and structure–activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors

Synthesis of 13R,20-dihydroxy-docosahexaenoic acid by site-directed mutagenesis of lipoxygenase derived from Oscillatoria nigro-viridis PCC 7112

First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis

Arabidopsis lipoxygenase 2 is essential for formation of green leaf volatiles and five‐carbon volatiles

Genome-wide identification, classification and expression of lipoxygenase gene family in pepper

Synthesis, characterization and anti-inflammatory properties of karanjin (Pongamia pinnata seed) and its derivatives

Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers

Novel cinnamic acid derivatives as antioxidant and anticancer agents: design, synthesis and modeling studies

Investigating anti-inflammatory actions of marine algal compound against lipoxygenase concentrating on therapeutic applications through computational approach

Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity

Effect of biotic stress on the presence of secondary metabolites in field pea grains

Structure and ligand based drug design strategies in the development of novel 5- LOX inhibitors

Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease

Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts

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