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Exploring the 2'-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

Molecules (Basel, Switzerland), 2021-05, Vol.26 (9), p.2777

2021

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Mammalian lipoxygenases and their biological relevance

Biochimica et biophysica acta, 2015-04, Vol.1851 (4), p.308-330

2015

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Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis

Molecular psychiatry, 2021-11, Vol.26 (11), p.6773-6788

2021

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Lipoxygenases – Structure and reaction mechanism

Phytochemistry (Oxford), 2009-09, Vol.70 (13), p.1504-1510

2009

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Fragment-based design, docking, synthesis, biological evaluation and structure–activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors

European journal of medicinal chemistry, 2012, Vol.47 (1), p.111-124

2012

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First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis

Arteriosclerosis, thrombosis, and vascular biology, 2017-10, Vol.37 (10), p.1828-1839

2017

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Synthesis, characterization and anti-inflammatory properties of karanjin (Pongamia pinnata seed) and its derivatives

Bioorganic chemistry, 2021-01, Vol.106, p.104471, Article 104471

2021

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Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers

Molecules (Basel, Switzerland), 2021-02, Vol.26 (5), p.1201

2021

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Genome-wide identification and classification of Lipoxygenase gene family and their roles in sorghum-aphid interaction

Plant molecular biology, 2021-03, Vol.105 (4-5), p.527-541

2021

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Novel cinnamic acid derivatives as antioxidant and anticancer agents: design, synthesis and modeling studies

Molecules (Basel, Switzerland), 2014-07, Vol.19 (7), p.9655-9674

2014

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Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity

Bioorganic & medicinal chemistry, 2009-12, Vol.17 (23), p.8073-8085

2009

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Investigating anti-inflammatory actions of marine algal compound against lipoxygenase concentrating on therapeutic applications through computational approach

Journal of biomolecular structure & dynamics, 2024-11, Vol.42 (17), p.9050-9063

2024

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Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts

European journal of medicinal chemistry, 2009-07, Vol.44 (7), p.3020-3026

2009

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Synthesis and Antioxidant Activity of N -Benzyl-2-[4-(aryl)-1 H -1,2,3-triazol-1-yl]ethan-1-imine Oxides

International journal of molecular sciences, 2024-06, Vol.25 (11), p.5908

2024

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Structural modifications of coumarin derivatives: Determination of antioxidant and lipoxygenase (LOX) inhibitory activity

Bioorganic & medicinal chemistry, 2014-12, Vol.22 (23), p.6586-6594

2014

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Structural considerations on lipoxygenase function, inhibition and crosstalk with nitric oxide pathways

Biochimie, 2020-11, Vol.178, p.170-180

2020

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Synthesis, Bioactivity, Pharmacokinetic and Biomimetic Properties of Multi-Substituted Coumarin Derivatives

Molecules (Basel, Switzerland), 2021-10, Vol.26 (19), p.5999

2021

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Multifunctional Cinnamic Acid Derivatives

Molecules (Basel, Switzerland), 2017-07, Vol.22 (8), p.1247

2017

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Genome-wide identification, classification and expression of lipoxygenase gene family in pepper

Plant molecular biology, 2018-11, Vol.98 (4-5), p.375-387

2018

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Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2

Bioorganic & medicinal chemistry, 2021-09, Vol.46, p.116349-116349, Article 116349

2021

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Computational analysis of eugenol inhibitory activity in lipoxygenase and cyclooxygenase pathways

Scientific reports, 2020-10, Vol.10 (1), p.16204-16204, Article 16204

2020

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Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products

Nature chemical biology, 2020-07, Vol.16 (7), p.783-790

2020

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Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis

Cell chemical biology, 2020-04, Vol.27 (4), p.387-408

2020

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Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (34), p.E4966-E4975

2016

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Regiospecificity of a novel bacterial lipoxygenase from Myxococcus xanthus for polyunsaturated fatty acids

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2018-08, Vol.1863 (8), p.823-833

2018

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Exploring the 2'-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

Mammalian lipoxygenases and their biological relevance

Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis

Lipoxygenases – Structure and reaction mechanism

Fragment-based design, docking, synthesis, biological evaluation and structure–activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors

First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis

Synthesis, characterization and anti-inflammatory properties of karanjin (Pongamia pinnata seed) and its derivatives

Phytochemical Profile, Antioxidant Activity, and Cytotoxicity Assessment of Tagetes erecta L. Flowers

Genome-wide identification and classification of Lipoxygenase gene family and their roles in sorghum-aphid interaction

Novel cinnamic acid derivatives as antioxidant and anticancer agents: design, synthesis and modeling studies

Natural and synthetic 2′-hydroxy-chalcones and aurones: Synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity

Investigating anti-inflammatory actions of marine algal compound against lipoxygenase concentrating on therapeutic applications through computational approach

Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts

Synthesis and Antioxidant Activity of N -Benzyl-2-[4-(aryl)-1 H -1,2,3-triazol-1-yl]ethan-1-imine Oxides

Structural modifications of coumarin derivatives: Determination of antioxidant and lipoxygenase (LOX) inhibitory activity

Structural considerations on lipoxygenase function, inhibition and crosstalk with nitric oxide pathways

Synthesis, Bioactivity, Pharmacokinetic and Biomimetic Properties of Multi-Substituted Coumarin Derivatives

Multifunctional Cinnamic Acid Derivatives

Genome-wide identification, classification and expression of lipoxygenase gene family in pepper

Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2

Computational analysis of eugenol inhibitory activity in lipoxygenase and cyclooxygenase pathways

Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products

Achieving Life through Death: Redox Biology of Lipid Peroxidation in Ferroptosis

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Regiospecificity of a novel bacterial lipoxygenase from Myxococcus xanthus for polyunsaturated fatty acids

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