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Engineering allosteric transcription factors guided by the LacI topology

Cell systems, 2023-08, Vol.14 (8), p.645-655

2023

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Substitutions at Nonconserved Rheostat Positions Modulate Function by Rewiring Long-Range, Dynamic Interactions

Molecular biology and evolution, 2021-01, Vol.38 (1), p.201-214

2021

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A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli

Microbial cell factories, 2013-03, Vol.12 (1), p.26-26, Article 26

2013

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Development of the Low-Temperature Inducible System for Recombinant Protein Production in Escherichia coli Nissle 1917

Journal of agricultural and food chemistry, 2024-04, Vol.72 (13), p.7318-7325

2024

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Characterization of a transcriptional regulator PtxS from Pseudomonas plecoglossicida for regulating 2-ketogluconic acid metabolism

International journal of biological macromolecules, 2021-03, Vol.174, p.330-338

2021

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Exploring the sequence–function relationship in transcriptional regulation by the lac O 1 operator

The FEBS journal, 2012-07, Vol.279 (14), p.2534-2543

2012

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LipR functions as an intracellular pH regulator in Bacillus thuringiensis under glucose conditions

mLife, 2023-03, Vol.2 (1), p.58-72

2023

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Genetic tools for reliable gene expression and recombineering in Pseudomonas putida

Journal of industrial microbiology & biotechnology, 2018-07, Vol.45 (7), p.517-527

2018

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Imaging of genomic loci in Trypanosoma brucei using an optimised LacO-LacI system

Molecular and biochemical parasitology, 2023-12, Vol.256, p.111598-111598, Article 111598

2023

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Cardiovascular magnetic resonance rest and exercise-stress left atrioventricular coupling index to detect diastolic dysfunction

American journal of physiology. Heart and circulatory physiology, 2023-05, Vol.324 (5), p.H686-H695

2023

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LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in Streptomyces coelicolor A3(2)

Frontiers in microbiology, 2021-04, Vol.12, p.658657-658657

2021

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RETRACTED: LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in Streptomyces coelicolor A3(2)

Frontiers in microbiology, 2021-04, Vol.12

2021

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Computational predictors fail to identify amino acid substitution effects at rheostat positions

Scientific reports, 2017-01, Vol.7 (1), p.41329-41329, Article 41329

2017

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Long‐term evolution of the natural isolate of Escherichia coli 536 in the mouse gut colonized after maternal transmission reveals convergence in the constitutive expression of the lactose operon

Molecular ecology, 2019-10, Vol.28 (19), p.4470-4485

2019

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Deep representation learning improves prediction of LacI-mediated transcriptional repression

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (27), p.1

2021

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Simulated pressure changes in LacI suggest a link between hydration and functional conformational changes

Biophysical chemistry, 2024-01, Vol.304, p.107126-107126, Article 107126

2024

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SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions

The Journal of cell biology, 2021-01, Vol.220 (1)

2021

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Structural basis of a novel repressor, SghR, controlling Agrobacterium infection by cross-talking to plants

The Journal of biological chemistry, 2020-08, Vol.295 (34), p.12290-12304

2020

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RheoScale: A tool to aggregate and quantify experimentally determined substitution outcomes for multiple variants at individual protein positions

Human mutation, 2018-12, Vol.39 (12), p.1814-1826

2018

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Design and analysis of LacI-repressed promoters and DNA-looping in a cyanobacterium

Journal of biological engineering, 2014-01, Vol.8 (1), p.4-4, Article 4

2014

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Condensin-Mediated Chromosome Folding and Internal Telomeres Drive Dicentric Severing by Cytokinesis

Molecular cell, 2019-07, Vol.75 (1), p.131-144.e3

2019

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Engineered temperature compensation in a synthetic genetic clock

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (3), p.972-977

2014

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The lac repressor hinge helix in context: The effect of the DNA binding domain and symmetry

Biochimica et biophysica acta. General subjects, 2020-04, Vol.1864 (4), p.129538-129538, Article 129538

2020

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Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene

Molecular biology and evolution, 2020-05, Vol.37 (5), p.1329-1341

2020

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Development and optimization of a modular two-fragment LacI switch for enhanced biosensor applications

Biotechnology and Bioprocess Engineering, 2024, 29(1), , pp.109-117

2024

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Engineering allosteric transcription factors guided by the LacI topology

Substitutions at Nonconserved Rheostat Positions Modulate Function by Rewiring Long-Range, Dynamic Interactions

A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli

Development of the Low-Temperature Inducible System for Recombinant Protein Production in Escherichia coli Nissle 1917

Characterization of a transcriptional regulator PtxS from Pseudomonas plecoglossicida for regulating 2-ketogluconic acid metabolism

Exploring the sequence–function relationship in transcriptional regulation by the lac O 1 operator

LipR functions as an intracellular pH regulator in Bacillus thuringiensis under glucose conditions

Genetic tools for reliable gene expression and recombineering in Pseudomonas putida

Imaging of genomic loci in Trypanosoma brucei using an optimised LacO-LacI system

Cardiovascular magnetic resonance rest and exercise-stress left atrioventricular coupling index to detect diastolic dysfunction

LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in Streptomyces coelicolor A3(2)

RETRACTED: LacI-Family Transcriptional Regulator DagR Acts as a Repressor of the Agarolytic Pathway Genes in Streptomyces coelicolor A3(2)

Computational predictors fail to identify amino acid substitution effects at rheostat positions

Long‐term evolution of the natural isolate of Escherichia coli 536 in the mouse gut colonized after maternal transmission reveals convergence in the constitutive expression of the lactose operon

Deep representation learning improves prediction of LacI-mediated transcriptional repression

Simulated pressure changes in LacI suggest a link between hydration and functional conformational changes

SLX4-XPF mediates DNA damage responses to replication stress induced by DNA-protein interactions

Structural basis of a novel repressor, SghR, controlling Agrobacterium infection by cross-talking to plants

RheoScale: A tool to aggregate and quantify experimentally determined substitution outcomes for multiple variants at individual protein positions

Design and analysis of LacI-repressed promoters and DNA-looping in a cyanobacterium

Condensin-Mediated Chromosome Folding and Internal Telomeres Drive Dicentric Severing by Cytokinesis

Engineered temperature compensation in a synthetic genetic clock

The lac repressor hinge helix in context: The effect of the DNA binding domain and symmetry

Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene

Development and optimization of a modular two-fragment LacI switch for enhanced biosensor applications

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