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Polarized focal adhesion kinase activity within a focal adhesion during cell migration

Nature chemical biology, 2023-12, Vol.19 (12), p.1458

2023

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lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Molecular therapy, 2022-02, Vol.30 (2), p.688-702

2022

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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

Scientific reports, 2018-05, Vol.8 (1), p.7228-20, Article 7228

2018

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FAK controls the mechanical activation of YAP, a transcriptional regulator required for durotaxis

The FASEB journal, 2018-02, Vol.32 (2), p.1099-1107

2018

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CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling

Nature cell biology, 2021-07, Vol.23 (7), p.758

2021

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Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer

Journal of experimental & clinical cancer research, 2018-07, Vol.37 (1), p.175-175, Article 175

2018

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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

The Journal of cell biology, 2007-02, Vol.176 (5), p.667-680

2007

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Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules

Nutrients, 2017-09, Vol.9 (10), p.1073

2017

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YAP regulates cell mechanics by controlling focal adhesion assembly

Nature communications, 2017-05, Vol.8 (1), p.15321-15321, Article 15321

2017

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Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

The Journal of cell biology, 2016-02, Vol.212 (3), p.349-364

2016

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FAK dimerization controls its kinase-dependent functions at focal adhesions

The EMBO journal, 2014-02, Vol.33 (4), p.356-370

2014

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Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells

The Journal of cell biology, 2018-01, Vol.217 (1), p.375-395

2018

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ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis through PI3K/Akt Signaling and MAPK-Dependent Focal Adhesion Disassembly

Cancer research (Chicago, Ill.), 2021-02, Vol.81 (4), p.986-1000

2021

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A post-invasion role for Chlamydia type III effector TarP in modulating the dynamics and organization of host cell focal adhesions

The Journal of biological chemistry, 2020-10, Vol.295 (43), p.14763-14779

2020

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Phosphorylated paxillin and phosphorylated FAK constitute subregions within focal adhesions

Journal of cell science, 2022-04, Vol.135 (7)

2022

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Altering FAK-paxillin interactions reduces adhesion, migration and invasion processes

PloS one, 2014-03, Vol.9 (3), p.e92059

2014

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Distinct focal adhesion protein modules control different aspects of mechanotransduction

Journal of cell science, 2017-05, Vol.130 (9), p.1612-1624

2017

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Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2508-2520

2019

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Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

Nature communications, 2021-04, Vol.12 (1), p.2359-2359, Article 2359

2021

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ECT2 promotes lung adenocarcinoma progression through extracellular matrix dynamics and focal adhesion signaling

Cancer science, 2021-02, Vol.112 (2), p.703-714

2021

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Cardiac Differentiation Promotes Focal Adhesions Assembly through Vinculin Recruitment

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2444

2023

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Vinculin controls talin engagement with the actomyosin machinery

Nature communications, 2015-12, Vol.6 (1), p.10038-10038, Article 10038

2015

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Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling

Molecular pharmacology, 2016-05, Vol.89 (5), p.521-540

2016

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Focal adhesions: a personal perspective on a half century of progress

The FEBS journal, 2017-10, Vol.284 (20), p.3355-3361

Burridge, Keith

2017

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The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions

Cancer discovery, 2012-08, Vol.2 (8), p.706-721

2012

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