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Ribosome-inactivating proteins: Potent poisons and molecular tools

Virulence, 2013-11, Vol.4 (8), p.774-784

2013

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Antidepressant actions of ketamine engage cell-specific translation via eIF4E

Nature (London), 2021-02, Vol.590 (7845), p.315-319

2021

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eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6439), p.491-495

2019

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Amygdala inhibitory neurons as loci for translation in emotional memories

Nature (London), 2020-10, Vol.586 (7829), p.407-411

2020

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Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis

PLoS pathogens, 2018-08, Vol.14 (8), p.e1007264-e1007264

2018

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The ribosome‐associated chaperone Zuo1 controls translation upon TORC1 inhibition

The EMBO journal, 2023-12, Vol.42 (24), p.e113240-n/a

2023

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Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation

Nature neuroscience, 2020-02, Vol.23 (2), p.281

2020

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The role of host eIF2α in viral infection

Virology journal, 2020-07, Vol.17 (1), p.112-112, Article 112

2020

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Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis

Science (American Association for the Advancement of Science), 2002-01, Vol.295 (5552), p.140-143

2002

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Natural products as drugs and tools for influencing core processes of eukaryotic mRNA translation

Pharmacological research, 2021-08, Vol.170, p.105535-105535, Article 105535

2021

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Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol

PloS one, 2009-04, Vol.4 (4), p.e5223-e5223

2009

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Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells

PloS one, 2010-12, Vol.5 (12), p.e14363-e14363

2010

Volltextzugriff (PDF)

Inhibition of the Interferon-Inducible Protein Kinase PKR by HCV E2 Protein

Science (American Association for the Advancement of Science), 1999-07, Vol.285 (5424), p.107-110

1999

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Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective

PloS one, 2016-04, Vol.11 (4), p.e0153680-e0153680

2016

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6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress

PloS one, 2012-06, Vol.7 (6), p.e39664

2012

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Autophagy inhibition by biotin elicits endoplasmic reticulum stress to differentially regulate adipocyte lipid and protein synthesis

Cell stress & chaperones, 2019-03, Vol.24 (2), p.343-350

2019

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Activation of the unfolded protein response in sarcoma cells treated with rapamycin or temsirolimus

PloS one, 2017-09, Vol.12 (9), p.e0185089

2017

Volltextzugriff (PDF)

Legionella pneumophila Glucosyltransferase Inhibits Host Elongation Factor 1A

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (45), p.16953-16958

2006

Volltextzugriff (PDF)

Resveratrol inhibits protein translation in hepatic cells

PloS one, 2011-12, Vol.6 (12), p.e29513

2011

Volltextzugriff (PDF)

Role of PKR in the Inhibition of Proliferation and Translation by Polycystin-1

BioMed research international, 2019-01, Vol.2019, p.5320747-8

2019

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Carbon monoxide releasing molecule-2 CORM-2 represses global protein synthesis by inhibition of eukaryotic elongation factor eEF2

The international journal of biochemistry & cell biology, 2013-02, Vol.45 (2), p.201-212

2013

Volltextzugriff (PDF)

Regulation of mRNA Translation Is a Novel Mechanism for Phthalate Toxicity

PloS one, 2016-12, Vol.11 (12), p.e0167914

2016

Volltextzugriff (PDF)

HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage

PloS one, 2009-11, Vol.4 (11), p.e7997-e7997

2009

Volltextzugriff (PDF)

Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms

PloS one, 2011-11, Vol.6 (11), p.e27904-e27904

2011

Volltextzugriff (PDF)

eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease

PloS one, 2010-09, Vol.5 (9), p.e13030

2010

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Ribosome-inactivating proteins: Potent poisons and molecular tools

Antidepressant actions of ketamine engage cell-specific translation via eIF4E

eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response

Amygdala inhibitory neurons as loci for translation in emotional memories

Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis

The ribosome‐associated chaperone Zuo1 controls translation upon TORC1 inhibition

Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation

The role of host eIF2α in viral infection

Tumstatin, an Endothelial Cell-Specific Inhibitor of Protein Synthesis

Natural products as drugs and tools for influencing core processes of eukaryotic mRNA translation

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol

Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells

Inhibition of the Interferon-Inducible Protein Kinase PKR by HCV E2 Protein

Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective

6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress

Autophagy inhibition by biotin elicits endoplasmic reticulum stress to differentially regulate adipocyte lipid and protein synthesis

Activation of the unfolded protein response in sarcoma cells treated with rapamycin or temsirolimus

Legionella pneumophila Glucosyltransferase Inhibits Host Elongation Factor 1A

Resveratrol inhibits protein translation in hepatic cells

Role of PKR in the Inhibition of Proliferation and Translation by Polycystin-1

Carbon monoxide releasing molecule-2 CORM-2 represses global protein synthesis by inhibition of eukaryotic elongation factor eEF2

Regulation of mRNA Translation Is a Novel Mechanism for Phthalate Toxicity

HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage

Protein synthesis attenuation by phosphorylation of eIF2α is required for the differentiation of Trypanosoma cruzi into infective forms

eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease

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