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Deconstructing and reconstructing the mouse and human early embryo

Nature cell biology, 2018-08, Vol.20 (8), p.878-887

2018

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Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (3), p.E291-E299

2016

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Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells

Cell, 2020-04, Vol.181 (3), p.621-636.e22

2020

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Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12426-12431

2014

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Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

Nature cell biology, 2019-02, Vol.21 (2), p.263-274

2019

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Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

Nature (London), 2015-02, Vol.518 (7539), p.413-416

2015

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Blastocyst-like structures generated from human pluripotent stem cells

Nature (London), 2021-03, Vol.591 (7851), p.620-626

2021

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Embryonic stem cell potency fluctuates with endogenous retrovirus activity

Nature (London), 2012-07, Vol.487 (7405), p.57-63

2012

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Formative pluripotency: the executive phase in a developmental continuum

Development (Cambridge), 2017-02, Vol.144 (3), p.365-373

Smith, Austin

2017

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SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation

Genome Biology, 2018-10, Vol.19 (1), p.161-161, Article 161

2018

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Mouse totipotent stem cells captured and maintained through spliceosomal repression

Cell, 2021-05, Vol.184 (11), p.2843-2859.e20

2021

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A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization

Developmental cell, 2016-11, Vol.39 (3), p.302-315

2016

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Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (20), p.9222-9227

2010

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Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

Cell reports (Cambridge), 2017-10, Vol.21 (2), p.517-532

2017

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Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

Cell, 2011-08, Vol.146 (4), p.519-532

2011

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Stem-cell-based embryo models for fundamental research and translation

Nature materials, 2021-02, Vol.20 (2), p.132-144

2021

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HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

The EMBO journal, 2012-05, Vol.31 (9), p.2103-2116

2012

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Self-organization of the in vitro attached human embryo

Nature (London), 2016-05, Vol.533 (7602), p.251-254

2016

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Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes

Journal of hepatology, 2015-03, Vol.62 (3), p.581-589

2015

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Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

Nature (London), 2020-06, Vol.582 (7812), p.405-409

2020

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Human pluripotent stem cell-derived neural constructs for predicting neural toxicity

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.12516-12521

2015

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Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

The EMBO journal, 2015-07, Vol.34 (13), p.1759-1772

2015

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Enrichment of human embryonic stem cell‐derived NKX6.1‐expressing pancreatic progenitor cells accelerates the maturation of insulin‐secreting cells in vivo

Stem cells (Dayton, Ohio), 2013-11, Vol.31 (11), p.2432-2442

2013

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Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

Cell stem cell, 2017-01, Vol.20 (1), p.135-148

2017

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Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

Nature (London), 2012-09, Vol.489 (7415), p.304-308

2012

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Deconstructing and reconstructing the mouse and human early embryo

Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides

Distinct Processing of lncRNAs Contributes to Non-conserved Functions in Stem Cells

Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential

Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

Blastocyst-like structures generated from human pluripotent stem cells

Embryonic stem cell potency fluctuates with endogenous retrovirus activity

Formative pluripotency: the executive phase in a developmental continuum

SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation

Mouse totipotent stem cells captured and maintained through spliceosomal repression

A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

Stem-cell-based embryo models for fundamental research and translation

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

Self-organization of the in vitro attached human embryo

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes

Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids

Human pluripotent stem cell-derived neural constructs for predicting neural toxicity

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

Enrichment of human embryonic stem cell‐derived NKX6.1‐expressing pancreatic progenitor cells accelerates the maturation of insulin‐secreting cells in vivo

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

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