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Echinocandin Resistance in Candida

Clinical infectious diseases, 2015-12, Vol.61 (suppl_6), p.S612-S617

Perlin, David S.

2015

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Safety and Pharmacokinetics of CD101 IV, a Novel Echinocandin, in Healthy Adults

Antimicrobial agents and chemotherapy, 2017-02, Vol.61 (2)

2017

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Echinocandins: production and applications

Applied microbiology and biotechnology, 2013-04, Vol.97 (8), p.3267-3284

2013

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Echinocandin Antifungal Drugs in Fungal Infections: A Comparison

Drugs (New York, N.Y.), 2011, Vol.71 (1), p.11-41

2011

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Disseminated Candidiasis Caused by Candida albicans with Amino Acid Substitutions in Fks1 at Position Ser645 Cannot Be Successfully Treated with Micafungin

Antimicrobial Agents and Chemotherapy, 2011-07, Vol.55 (7), p.3075-3083

2011

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Echinocandins in antifungal pharmacotherapy

Journal of pharmacy and pharmacology, 2017-12, Vol.69 (12), p.1635-1660

2017

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Unnatural tetradeoxy echinocandins produced by gene cluster design and heterologous expression

Organic & biomolecular chemistry, 2023-05, Vol.21 (17), p.3552-3556

2023

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Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin

Antimicrobial agents and chemotherapy, 2016-11, Vol.60 (11), p.6872-6879

2016

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Structure-Activity Relationships of a Series of Echinocandins and the Discovery of CD101, a Highly Stable and Soluble Echinocandin with Distinctive Pharmacokinetic Properties

Antimicrobial agents and chemotherapy, 2017-02, Vol.61 (2)

2017

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Echinocandins: The Expanding Antifungal Armamentarium

Clinical infectious diseases, 2015-12, Vol.61 (suppl_6), p.S604-S611

2015

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Pharmacodynamic Optimization for Treatment of Invasive Candida auris Infection

Antimicrobial agents and chemotherapy, 2017-08, Vol.61 (8)

2017

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Reshaping Echinocandin Antifungal Drugs To Circumvent Glucan Synthase Point‐Mutation‐Mediated Resistance

Angewandte Chemie International Edition, 2024-02, Vol.63 (9), p.e202314728-n/a

International ed. in English, 2024

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Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-abdominal Abscess Model

Antimicrobial agents and chemotherapy, 2017-10, Vol.61 (10)

2017

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Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters

Antimicrobial agents and chemotherapy, 2017-11, Vol.61 (11)

2017

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Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008

PloS one, 2014-07, Vol.9 (7), p.e101510-e101510

2014

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Biosynthesis of pneumocandin lipopeptides and perspectives for its production and related echinocandins

Applied microbiology and biotechnology, 2018-12, Vol.102 (23), p.9881-9891

2018

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An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment

mBio, 2022-04, Vol.13 (2), p.e0293321-e0293321

2022

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High-Dose Micafungin for Preterm Neonates and Infants with Invasive and Central Nervous System Candidiasis

Antimicrobial agents and chemotherapy, 2016-12, Vol.60 (12), p.7333-7339

2016

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Echinocandin B biosynthesis: a biosynthetic cluster from Aspergillus nidulans NRRL 8112 and reassembly of the subclusters Ecd and Hty from Aspergillus pachycristatus NRRL 11440 reveals a single coherent gene cluster

BMC genomics, 2016-08, Vol.17 (1), p.570-570, Article 570

2016

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Echinocandin resistance: an emerging clinical problem?

Current opinion in infectious diseases, 2014-12, Vol.27 (6), p.484-492

2014

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Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations

Clinical infectious diseases, 2013-06, Vol.56 (12), p.1724-1732

2013

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Low Caspofungin Exposure in Patients in Intensive Care Units

Antimicrobial agents and chemotherapy, 2017-02, Vol.61 (2)

2017

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Pharmacokinetics of caspofungin in ICU patients

Journal of antimicrobial chemotherapy, 2014-12, Vol.69 (12), p.3294-3299

2014

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In Vivo Comparison of the Pharmacodynamic Targets for Echinocandin Drugs against Candida Species

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2497-2506

2010

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Echinocandins - structure, mechanism of action and use in antifungal therapy

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.876-894

2022

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