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Pharmacokinetic considerations when prescribing in children

International journal of pharmacokinetics, 2016-11, Vol.1 (1), p.69-80

2016

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Regulation of solute carriers oct2 and OAT1/3 in the kidney: a phylogenetic, ontogenetic, and cell dynamic perspective

Physiological reviews, 2022-04, Vol.102 (2), p.993-1024

2022

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Recent advances in the ontogeny of drug disposition

British journal of clinical pharmacology, 2022-10, Vol.88 (10), p.4267-4284

2022

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Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

Journal of clinical pharmacology, 2019-09, Vol.59 (S1), p.S56-S69

2019

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Editorial: Genetics and ontogeny in precision therapeutics for children

Frontiers in genetics, 2023, Vol.14, p.1308169-1308169

2023

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Drug Transporters Expressed in the Human Placenta and Models for Studying Maternal‐Fetal Drug Transfer

Journal of clinical pharmacology, 2019-09, Vol.59 (S1), p.S70-S81

2019

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Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients

International journal of pharmaceutics, 2024-04, Vol.654, p.123962-123962, Article 123962

2024

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IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

Blood, 2008-02, Vol.111 (4), p.2101-2111

2008

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Pharmacokinetics of Hydrochlorothiazide in Children: A Potential Surrogate for Renal Secretion Maturation

Journal of clinical pharmacology, 2021-03, Vol.61 (3), p.368-377

2021

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Regulation of hepatic bile acid transporters Ntcp and Bsep expression

Biochemical pharmacology, 2007-12, Vol.74 (11), p.1665-1676

2007

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Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation

The AAPS journal, 2015-11, Vol.17 (6), p.1376-1387

2015

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Dose adjustment in orphan disease populations: the quest to fulfill the requirements of physiologically based pharmacokinetics

Expert opinion on drug metabolism & toxicology, 2018-12, Vol.14 (12), p.1315-1330

2018

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Age-associated differences in transporter gene expression in kidneys of male rats

Molecular medicine reports, 2017-01, Vol.15 (1), p.474-482

2017

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Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication

Expert opinion on drug metabolism & toxicology, 2018-06, Vol.14 (6), p.561-570

2018

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IL-7–induced proliferation of recent thymic emigrants requires activation of the PI3K pathway

Blood, 2007-02, Vol.109 (3), p.1034-1042

2007

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Transcriptomic insights on the ABC transporter gene family in the salmon louse Caligus rogercresseyi

Parasites & vectors, 2015-04, Vol.8 (1), p.209-209, Article 209

2015

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Developmental Pharmacogenetics of SLCO2B1 on Montelukast Pharmacokinetics in Chinese Children

Drug design, development and therapy, 2019-01, Vol.13, p.4405-4411

2019

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A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

Clinical and translational science, 2022-10, Vol.15 (10), p.2392-2402

2022

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P-glycoprotein in the developing human brain: a review of the effects of ontogeny on the safety of opioids in neonates

Therapeutic drug monitoring, 2014-12, Vol.36 (6), p.699

2014

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Ontogeny of cocaine-induced behaviors and cocaine pharmacokinetics in male and female neonatal, preweanling, and adult rats

Psychopharmacology, 2018-07, Vol.235 (7), p.1967-1980

2018

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Mind the Gaps: Ontogeny of Human Brain P-gp and Its Impact on Drug Toxicity

The AAPS journal, 2019-07, Vol.21 (4), p.67-67, Article 67

2019

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mRNA expression of drug metabolism enzymes and transporter genes at birth using human umbilical cord blood

Fundamental & clinical pharmacology, 2018-08, Vol.32 (4), p.422-435

2018

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Disturbed development of the enteric nervous system after in utero exposure of selective serotonin re‐uptake inhibitors and tricyclic antidepressants. Part 1: Literature review

British journal of clinical pharmacology, 2012-01, Vol.73 (1), p.16-26

2012

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Sex‐specific effects of leptin administration to pregnant mice on the placentae and the metabolic phenotypes of offspring

FEBS open bio, 2020-01, Vol.10 (1), p.96-106

2020

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Developmental pharmacogenetics of immunosuppressants in pediatric organ transplantation

Therapeutic drug monitoring, 2010-12, Vol.32 (6), p.688

2010

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Pharmacokinetic considerations when prescribing in children

Regulation of solute carriers oct2 and OAT1/3 in the kidney: a phylogenetic, ontogenetic, and cell dynamic perspective

Recent advances in the ontogeny of drug disposition

Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

Editorial: Genetics and ontogeny in precision therapeutics for children

Drug Transporters Expressed in the Human Placenta and Models for Studying Maternal‐Fetal Drug Transfer

Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients

IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

Pharmacokinetics of Hydrochlorothiazide in Children: A Potential Surrogate for Renal Secretion Maturation

Regulation of hepatic bile acid transporters Ntcp and Bsep expression

Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation

Dose adjustment in orphan disease populations: the quest to fulfill the requirements of physiologically based pharmacokinetics

Age-associated differences in transporter gene expression in kidneys of male rats

Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication

IL-7–induced proliferation of recent thymic emigrants requires activation of the PI3K pathway

Transcriptomic insights on the ABC transporter gene family in the salmon louse Caligus rogercresseyi

Developmental Pharmacogenetics of SLCO2B1 on Montelukast Pharmacokinetics in Chinese Children

A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

P-glycoprotein in the developing human brain: a review of the effects of ontogeny on the safety of opioids in neonates

Ontogeny of cocaine-induced behaviors and cocaine pharmacokinetics in male and female neonatal, preweanling, and adult rats

Mind the Gaps: Ontogeny of Human Brain P-gp and Its Impact on Drug Toxicity

mRNA expression of drug metabolism enzymes and transporter genes at birth using human umbilical cord blood

Disturbed development of the enteric nervous system after in utero exposure of selective serotonin re‐uptake inhibitors and tricyclic antidepressants. Part 1: Literature review

Sex‐specific effects of leptin administration to pregnant mice on the placentae and the metabolic phenotypes of offspring

Developmental pharmacogenetics of immunosuppressants in pediatric organ transplantation

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