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Chemical evolution of cyclic dinucleotides: Perspective of the analogs and their preparation

Tetrahedron, 2021-05, Vol.87, p.132096, Article 132096

2021

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Biotechnological production of cyclic dinucleotides—Challenges and opportunities

Biotechnology and bioengineering, 2022-03, Vol.119 (3), p.677-684

2022

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Sub/supercritical Fluid Chromatography Purification and Desalting of a Cyclic Dinucleotide STING Agonist

Journal of Chromatography A, 2021-08, Vol.1652, p.462356, Article 462356

2021

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Induction of tumor regression by intratumoral STING agonists combined with anti–programmed death‐L1 blocking antibody in a preclinical squamous cell carcinoma model

Head & neck, 2017-06, Vol.39 (6), p.1086-1094

2017

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A Multi-Enzyme Cascade Reaction for the Production of 2'3'-cGAMP

Biomolecules (Basel, Switzerland), 2021-04, Vol.11 (4)

2021

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Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy

Journal of clinical medicine, 2020-10, Vol.9 (10), p.3323

2020

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Co-administration of 2'3'-cGAMP STING activator and CpG-C adjuvants with a mutated form of HPV 16 E7 protein leads to tumor growth inhibition in the mouse model

Infectious agents and cancer, 2021-01, Vol.16 (1), p.7-7, Article 7

2021

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Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration

European journal of medicinal chemistry, 2022-08, Vol.238, p.114482-114482, Article 114482

2022

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Design, Synthesis and Biological Evaluation of (2',5' and 3'5'-Linked) cGAMP Analogs that Activate Stimulator of Interferon Genes (STING)

Molecules (Basel, Switzerland), 2020-11, Vol.25 (22), p.5285

2020

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Molecular dynamics simulations provide structural insight into binding of cyclic dinucleotides to human STING protein

Journal of biomolecular structure & dynamics, 2022-01, Vol.40 (20), p.10250-10264

2022

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Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model

Frontiers in immunology, 2022-04, Vol.13, p.878832-878832

2022

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The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells

Apoptosis (London), 2021-06, Vol.26 (5-6), p.293-306

2021

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Design, synthesis and systematic evaluation of all possible cyclic dinucleotides (CDNs) that activate human stimulator of interferon genes (STING) variants

Science China. Chemistry, 2020-04, Vol.63 (4), p.534-545

2020

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Novel and emerging innate immune therapeutic targets for pancreatic cancer

Expert opinion on therapeutic targets, 2018-12, Vol.22 (12), p.977-981

2018

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Recent advances in the activation and regulation of the cGAS-STING pathway

Advances in immunology, 2022, Vol.156, p.55-102

2022

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Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy

Recent patents on anti-cancer drug discovery, 2018-01, Vol.13 (1), p.2

2018

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SLC19A1 Is an Importer of the Immunotransmitter cGAMP

Molecular cell, 2019-07, Vol.75 (2), p.372-381.e5

2019

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RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread

mBio, 2018-05, Vol.9 (3)

2018

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Chemical evolution of cyclic dinucleotides: Perspective of the analogs and their preparation

Biotechnological production of cyclic dinucleotides—Challenges and opportunities

Sub/supercritical Fluid Chromatography Purification and Desalting of a Cyclic Dinucleotide STING Agonist

Induction of tumor regression by intratumoral STING agonists combined with anti–programmed death‐L1 blocking antibody in a preclinical squamous cell carcinoma model

A Multi-Enzyme Cascade Reaction for the Production of 2'3'-cGAMP

Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy

Co-administration of 2'3'-cGAMP STING activator and CpG-C adjuvants with a mutated form of HPV 16 E7 protein leads to tumor growth inhibition in the mouse model

Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration

Design, Synthesis and Biological Evaluation of (2',5' and 3'5'-Linked) cGAMP Analogs that Activate Stimulator of Interferon Genes (STING)

Molecular dynamics simulations provide structural insight into binding of cyclic dinucleotides to human STING protein

Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model

The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells

Design, synthesis and systematic evaluation of all possible cyclic dinucleotides (CDNs) that activate human stimulator of interferon genes (STING) variants

Novel and emerging innate immune therapeutic targets for pancreatic cancer

Recent advances in the activation and regulation of the cGAS-STING pathway

Nucleic Acid Sensing Machinery: Targeting Innate Immune System for Cancer Therapy

SLC19A1 Is an Importer of the Immunotransmitter cGAMP

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread

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