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Therapeutic‐like activity of cannabidiolic acid methyl ester in the MK‐801 mouse model of schizophrenia: Role for cannabinoid CB1 and serotonin‐1A receptors

The European journal of neuroscience, 2024-05, Vol.59 (9), p.2403-2415

2024

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Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa

FEBS letters, 2007-06, Vol.581 (16), p.2929-2934

2007

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Serum cannabidiol, tetrahydrocannabinol (THC), and their native acid derivatives after transdermal application of a low‐THC Cannabis sativa extract in beagles

Journal of veterinary pharmacology and therapeutics, 2020-09, Vol.43 (5), p.508-511

2020

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Development of a novel cannabinoid-loaded microemulsion towards an improved stability and transdermal delivery

International journal of pharmaceutics, 2021-07, Vol.604, p.120766-120766, Article 120766

2021

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Unraveling the molecular basis of cannabidiolic acid methyl Ester's anti-depressive effects in a rat model of treatment-resistant depression

Journal of psychiatric research, 2024-07, Vol.175, p.50-59

2024

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Pharmacokinetics of Cannabidiol, Cannabidiolic Acid, Δ9-Tetrahydrocannabinol, Tetrahydrocannabinolic Acid and Related Metabolites in Canine Serum After Dosing With Three Oral Forms of Hemp Extract

Frontiers in veterinary science, 2020-09, Vol.7, p.505-505

2020

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Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects

Frontiers in pharmacology, 2020-02, Vol.11, p.63-63

2020

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Effective determination of the principal non-psychoactive cannabinoids in fiber-type Cannabis sativa L. by UPLC-PDA following a comprehensive design and optimization of extraction methodology

Analytica chimica acta, 2021-03, Vol.1150, p.338200-338200, Article 338200

2021

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Elucidation of structure-function relationship of THCA and CBDA synthase from Cannabis sativa L

Journal of biotechnology, 2018-10, Vol.284, p.17-26

2018

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Improvement of cannabidiolic acid synthetase activity through molecular docking and site-directed mutagenesis

Industrial crops and products, 2024-02, Vol.208, p.117860, Article 117860

2024

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Chemical Analysis of Minor Bioactive Components and Cannabidiolic Acid in Commercial Hemp Seed Oil

Molecules (Basel, Switzerland), 2020-08, Vol.25 (16), p.3710

2020

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Rapid isolation of acidic cannabinoids from Cannabis sativa L. using pH-zone-refining centrifugal partition chromatography

Journal of Chromatography A, 2019-08, Vol.1599, p.196-202

2019

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Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets

Biochemical pharmacology, 2020-05, Vol.175, p.113859-113859, Article 113859

2020

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Cannabinoid synthases and osmoprotective metabolites accumulate in the exudates of Cannabis sativa L. glandular trichomes

Plant science (Limerick), 2019-07, Vol.284, p.108-116

2019

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(‒)-Cannabidiolic Acid, a Still Overlooked Bioactive Compound: An Introductory Review and Preliminary Research

Molecules (Basel, Switzerland), 2020-06, Vol.25 (11), p.2638

2020

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Lipid nano-carriers loaded with Cannabis sativa extract for epilepsy treatment - in vitro characterization and in vivo efficacy studies

Journal of pharmaceutical sciences, 2022-12, Vol.111 (12), p.3384-3396

2022

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Cannabidiol disrupts conditioned fear expression and cannabidiolic acid reduces trauma-induced anxiety-related behaviour in mice

Behavioural pharmacology, 2020-09, Vol.31 (6), p.591-596

2020

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Pharmacokinetics and tolerability of single-dose enteral cannabidiol and cannabidiolic acid rich hemp in horses ( Equus caballus )

Frontiers in veterinary science, 2024, Vol.11, p.1356463-1356463

2024

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Cannabidiolic acid exhibits entourage-like improvements of anticonvulsant activity in an acute rat model of seizures

Epilepsy research, 2021-01, Vol.169, p.106525-106525, Article 106525

2021

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Cannabidiol but not cannabidiolic acid reduces behavioural sensitisation to methamphetamine in rats, at pharmacologically effective doses

Psychopharmacology, 2022-05, Vol.239 (5), p.1593-1603

2022

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Safety and efficacy of cannabidiol-cannabidiolic acid rich hemp extract in the treatment of refractory epileptic seizures in dogs

Frontiers in veterinary science, 2022-07, Vol.9, p.939966-939966

2022

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Natural Salicylates and Their Roles in Human Health

International journal of molecular sciences, 2020-11, Vol.21 (23), p.9049

2020

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Chronic Treatment with Cannabidiolic Acid (CBDA) Reduces Thermal Pain Sensitivity in Male Mice and Rescues the Hyperalgesia in a Mouse Model of Rett Syndrome

Neuroscience, 2021-01, Vol.453, p.113-123

2021

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Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells

Archives of biochemistry and biophysics, 2022-11, Vol.731, p.109428, Article 109428

2022

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Serum Cannabinoid 24 h and 1 Week Steady State Pharmacokinetic Assessment in Cats Using a CBD/CBDA Rich Hemp Paste

Frontiers in veterinary science, 2022-07, Vol.9, p.895368-895368

2022

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Therapeutic‐like activity of cannabidiolic acid methyl ester in the MK‐801 mouse model of schizophrenia: Role for cannabinoid CB1 and serotonin‐1A receptors

Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa

Serum cannabidiol, tetrahydrocannabinol (THC), and their native acid derivatives after transdermal application of a low‐THC Cannabis sativa extract in beagles

Development of a novel cannabinoid-loaded microemulsion towards an improved stability and transdermal delivery

Unraveling the molecular basis of cannabidiolic acid methyl Ester's anti-depressive effects in a rat model of treatment-resistant depression

Pharmacokinetics of Cannabidiol, Cannabidiolic Acid, Δ9-Tetrahydrocannabinol, Tetrahydrocannabinolic Acid and Related Metabolites in Canine Serum After Dosing With Three Oral Forms of Hemp Extract

Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects

Effective determination of the principal non-psychoactive cannabinoids in fiber-type Cannabis sativa L. by UPLC-PDA following a comprehensive design and optimization of extraction methodology

Elucidation of structure-function relationship of THCA and CBDA synthase from Cannabis sativa L

Improvement of cannabidiolic acid synthetase activity through molecular docking and site-directed mutagenesis

Chemical Analysis of Minor Bioactive Components and Cannabidiolic Acid in Commercial Hemp Seed Oil

Rapid isolation of acidic cannabinoids from Cannabis sativa L. using pH-zone-refining centrifugal partition chromatography

Phytocannabinoids promote viability and functional adipogenesis of bone marrow-derived mesenchymal stem cells through different molecular targets

Cannabinoid synthases and osmoprotective metabolites accumulate in the exudates of Cannabis sativa L. glandular trichomes

(‒)-Cannabidiolic Acid, a Still Overlooked Bioactive Compound: An Introductory Review and Preliminary Research

Lipid nano-carriers loaded with Cannabis sativa extract for epilepsy treatment - in vitro characterization and in vivo efficacy studies

Cannabidiol disrupts conditioned fear expression and cannabidiolic acid reduces trauma-induced anxiety-related behaviour in mice

Pharmacokinetics and tolerability of single-dose enteral cannabidiol and cannabidiolic acid rich hemp in horses ( Equus caballus )

Cannabidiolic acid exhibits entourage-like improvements of anticonvulsant activity in an acute rat model of seizures

Cannabidiol but not cannabidiolic acid reduces behavioural sensitisation to methamphetamine in rats, at pharmacologically effective doses

Safety and efficacy of cannabidiol-cannabidiolic acid rich hemp extract in the treatment of refractory epileptic seizures in dogs

Natural Salicylates and Their Roles in Human Health

Chronic Treatment with Cannabidiolic Acid (CBDA) Reduces Thermal Pain Sensitivity in Male Mice and Rescues the Hyperalgesia in a Mouse Model of Rett Syndrome

Cannabidiolic acid activates the expression of the PPARβ/δ target genes in MDA-MB-231 cells

Serum Cannabinoid 24 h and 1 Week Steady State Pharmacokinetic Assessment in Cats Using a CBD/CBDA Rich Hemp Paste

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