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In Vitro and in Vivo Prevention of Human CD8+ CTL‐Mediated Xenocytotoxicity by Pig c‐FLIP Expression in Porcine Endothelial Cells

American journal of transplantation, 2008-02, Vol.8 (2), p.288-297

2008

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Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis

Nature (London), 2019-10, Vol.574 (7778), p.428-431

2019

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cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation

Science (American Association for the Advancement of Science), 2020-03, Vol.367 (6484), p.1379-1384

2020

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(‐)‐Epigallocatechin‐3‐gallate induced apoptosis by dissociation of c‐FLIP/Ku70 complex in gastric cancer cells

Journal of cellular and molecular medicine, 2023-09, Vol.27 (17), p.2572-2582

2023

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Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Nature communications, 2021-02, Vol.12 (1), p.819-17, Article 819

2021

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Controlling Cell Death through Post-translational Modifications of DED Proteins

Trends in cell biology, 2020-05, Vol.30 (5), p.354-369

2020

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RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development

Cell death and differentiation, 2019-05, Vol.26 (5), p.877-889

2019

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PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.11944-11949

2017

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Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways

Nature reviews. Immunology, 2012-02, Vol.12 (2), p.79

2012

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Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (19), p.E3796-E3805

2017

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TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis

Acta pharmacologica Sinica, 2023-08, Vol.44 (8), p.1649-1664

2023

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O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma

Oncogene, 2023-03, Vol.42 (10), p.725-736

2023

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Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis

Cell death and differentiation, 2017-12, Vol.24 (12), p.2127-2138

2017

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Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro

International journal of molecular sciences, 2019-02, Vol.20 (3), p.757

2019

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Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis

Nature communications, 2024-05, Vol.15 (1), p.3791-3791, Article 3791

2024

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Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP

Antioxidants & redox signaling, 2017-08, Vol.27 (4), p.215

2017

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The TRIF‐RIPK1‐Caspase‐8 signalling in the regulation of TLR4‐driven gene expression

Immunology, 2024-08, Vol.172 (4), p.566-576

2024

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Ro52/SSA sensitizes cells to death receptor-induced apoptosis by down-regulating c-FLIP(L)

Cell biology international, 2012-05, Vol.36 (5), p.463-468

2012

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Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

Cell death and differentiation, 2018-05, Vol.25 (5), p.951-965

2018

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The Immune Landscape of Thyroid Cancer in the Context of Immune Checkpoint Inhibition

International journal of molecular sciences, 2019-08, Vol.20 (16), p.3934

2019

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Immunohistopathological Study of c-FLIP Protein in Mycosis Fungoides

Asian Pacific journal of cancer prevention : APJCP, 2017-09, Vol.18 (9), p.2493-2499

2017

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Oncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment

Scientific reports, 2021-09, Vol.11 (1), p.18606-18606, Article 18606

2021

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Novel Midkine Inhibitor Induces Cell Cycle Arrest and Apoptosis in Multiple Myeloma

Anticancer research, 2024-03, Vol.44 (3), p.1023

2024

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Sodium tanshinone IIA sulfonate protects ARPE-19 cells against oxidative stress by inhibiting autophagy and apoptosis

Scientific reports, 2018-10, Vol.8 (1), p.15137-15, Article 15137

2018

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c-FLIP promotes drug resistance in non-small-cell lung cancer cells via upregulating FoxM1 expression

Acta pharmacologica Sinica, 2022-11, Vol.43 (11), p.2956-2966

2022

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In Vitro and in Vivo Prevention of Human CD8+ CTL‐Mediated Xenocytotoxicity by Pig c‐FLIP Expression in Porcine Endothelial Cells

Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis

cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation

(‐)‐Epigallocatechin‐3‐gallate induced apoptosis by dissociation of c‐FLIP/Ku70 complex in gastric cancer cells

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Controlling Cell Death through Post-translational Modifications of DED Proteins

RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development

PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP

Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways

Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis

TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis

O-GlcNAcylation of SPOP promotes carcinogenesis in hepatocellular carcinoma

Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis

Fluoxetine Induces Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits ERK/NF-κB-Modulated Anti-Apoptotic and Invasive Potential in Hepatocellular Carcinoma Cells In Vitro

Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis

Inhibition of Cathepsin S Induces Mitochondrial ROS That Sensitizes TRAIL-Mediated Apoptosis Through p53-Mediated Downregulation of Bcl-2 and c-FLIP

The TRIF‐RIPK1‐Caspase‐8 signalling in the regulation of TLR4‐driven gene expression

Ro52/SSA sensitizes cells to death receptor-induced apoptosis by down-regulating c-FLIP(L)

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

The Immune Landscape of Thyroid Cancer in the Context of Immune Checkpoint Inhibition

Immunohistopathological Study of c-FLIP Protein in Mycosis Fungoides

Oncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment

Novel Midkine Inhibitor Induces Cell Cycle Arrest and Apoptosis in Multiple Myeloma

Sodium tanshinone IIA sulfonate protects ARPE-19 cells against oxidative stress by inhibiting autophagy and apoptosis

c-FLIP promotes drug resistance in non-small-cell lung cancer cells via upregulating FoxM1 expression

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