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Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7491-7507

2020

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Boronic Acids and Their Derivatives in Medicinal Chemistry: Synthesis and Biological Applications

Molecules (Basel, Switzerland), 2020-09, Vol.25 (18), p.4323

2020

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Design and discovery of boronic acid drugs

European journal of medicinal chemistry, 2020-06, Vol.195, p.112270, Article 112270

2020

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Palladium-Catalyzed Difluoroalkylation of Aryl Boronic Acids: A New Method for the Synthesis of Aryldifluoromethylated Phosphonates and Carboxylic Acid Derivatives

Angewandte Chemie (International ed.), 2014-02, Vol.53 (6), p.1669-1673

International ed. in English, 2014

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Phenylboronic Acid Modification Augments the Lysosome Escape and Antitumor Efficacy of a Cylindrical Polymer Brush-Based Prodrug

Journal of the American Chemical Society, 2021-12, Vol.143 (49), p.20927-20938

2021

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Discovery of a Cyclic Boronic Acid β‑Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3682-3692

2015

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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the β-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects

Antimicrobial agents and chemotherapy, 2016-10, Vol.60 (10), p.6326-6332

2016

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The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

Annals of the rheumatic diseases, 2015-07, Vol.74 (7), p.1474-1478

2015

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Boronic Esters in Asymmetric Synthesis

Journal of organic chemistry, 2013-10, Vol.78 (20), p.10009-10023

Matteson, Donald S

2013

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Combined autophagy and proteasome inhibition: A phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma

Autophagy, 2014-08, Vol.10 (8), p.1380-1390

2014

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Boronic acids as building blocks for the construction of therapeutically useful bioconjugates

Chemical Society reviews, 2019-07, Vol.48 (13), p.3513-3536

2019

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Synthesis and Evaluation of Hydrogen Peroxide Sensitive Prodrugs of Methotrexate and Aminopterin for the Treatment of Rheumatoid Arthritis

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3503-3515

2018

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Proteasome inhibitors in multiple myeloma: 10 years later

Blood, 2012-08, Vol.120 (5), p.947-959

2012

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Highly Selective Fluorescent Probe Based on Hydroxylation of Phenylboronic Acid Pinacol Ester for Detection of Tyrosinase in Cells

Analytical chemistry (Washington), 2018-01, Vol.90 (1), p.855-858

2018

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Synthesis of Chiral α‑Amino Tertiary Boronic Esters by Enantioselective Hydroboration of α‑Arylenamides

Journal of the American Chemical Society, 2015-06, Vol.137 (21), p.6746-6749

2015

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Installation of an aryl boronic acid function into the external section of N-aryl-oxazolidinones: Synthesis and antimicrobial evaluation

European journal of medicinal chemistry, 2021-02, Vol.211, p.113002, Article 113002

2021

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Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain

Nature chemical biology, 2016-11, Vol.12 (11), p.931-936

2016

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Copper-Catalyzed Diastereo- and Enantioselective Desymmetrization of Cyclopropenes: Synthesis of Cyclopropylboronates

Journal of the American Chemical Society, 2014-11, Vol.136 (45), p.15833-15836

2014

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Enantioselective, Lewis Base-Catalyzed Carbosulfenylation of Alkenylboronates by 1,2-Boronate Migration

Journal of the American Chemical Society, 2018-11, Vol.140 (46), p.15621-15625

2018

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Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties

Advanced materials (Weinheim), 2016-01, Vol.28 (1), p.86-91

2016

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Enantio- and Diastereoselective Synthesis of 1,2-Hydroxyboronates through Cu-Catalyzed Additions of Alkylboronates to Aldehydes

Journal of the American Chemical Society, 2015-05, Vol.137 (19), p.6176-6179

2015

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A Synthetic Approach Toward a Self-Regulated Insulin Delivery System

Angewandte Chemie (International ed.), 2012-02, Vol.51 (9), p.2124-2128

International ed. in English, 2012

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Simple Access to Elusive α‑Boryl Carbanions and Their Alkylation: An Umpolung Construction for Organic Synthesis

Journal of the American Chemical Society, 2014-07, Vol.136 (30), p.10581-10584

2014

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Merging the Versatile Functionalities of Boronic Acid with Peptides

International journal of molecular sciences, 2021-11, Vol.22 (23), p.12958

2021

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Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases

Boronic Acids and Their Derivatives in Medicinal Chemistry: Synthesis and Biological Applications

Design and discovery of boronic acid drugs

Palladium-Catalyzed Difluoroalkylation of Aryl Boronic Acids: A New Method for the Synthesis of Aryldifluoromethylated Phosphonates and Carboxylic Acid Derivatives

Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: a randomized phase 3 PETHEMA/GEM study

Phenylboronic Acid Modification Augments the Lysosome Escape and Antitumor Efficacy of a Cylindrical Polymer Brush-Based Prodrug

Discovery of a Cyclic Boronic Acid β‑Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases

Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of the β-Lactamase Inhibitor Vaborbactam (RPX7009) in Healthy Adult Subjects

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

Boronic Esters in Asymmetric Synthesis

Combined autophagy and proteasome inhibition: A phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma

Boronic acids as building blocks for the construction of therapeutically useful bioconjugates

Synthesis and Evaluation of Hydrogen Peroxide Sensitive Prodrugs of Methotrexate and Aminopterin for the Treatment of Rheumatoid Arthritis

Proteasome inhibitors in multiple myeloma: 10 years later

Highly Selective Fluorescent Probe Based on Hydroxylation of Phenylboronic Acid Pinacol Ester for Detection of Tyrosinase in Cells

Synthesis of Chiral α‑Amino Tertiary Boronic Esters by Enantioselective Hydroboration of α‑Arylenamides

Installation of an aryl boronic acid function into the external section of N-aryl-oxazolidinones: Synthesis and antimicrobial evaluation

Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain

Copper-Catalyzed Diastereo- and Enantioselective Desymmetrization of Cyclopropenes: Synthesis of Cyclopropylboronates

Enantioselective, Lewis Base-Catalyzed Carbosulfenylation of Alkenylboronates by 1,2-Boronate Migration

Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties

Enantio- and Diastereoselective Synthesis of 1,2-Hydroxyboronates through Cu-Catalyzed Additions of Alkylboronates to Aldehydes

A Synthetic Approach Toward a Self-Regulated Insulin Delivery System

Simple Access to Elusive α‑Boryl Carbanions and Their Alkylation: An Umpolung Construction for Organic Synthesis

Merging the Versatile Functionalities of Boronic Acid with Peptides

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