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HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia

Nature (London), 2014-10, Vol.514 (7521), p.242-246

2014

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Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia

Blood, 2015-10, Vol.126 (17), p.2031-2037

2015

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Non-transferrin-bound iron transporters

Free radical biology & medicine, 2019-03, Vol.133, p.101-111

Knutson, Mitchell D.

2019

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Hepcidin agonists as therapeutic tools

Blood, 2018-04, Vol.131 (16), p.1790-1794

2018

Volltextzugriff (PDF)

Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and β-thalassemia

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (38), p.10661-10665

2016

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Co-transcriptional splicing regulates 3′ end cleavage during mammalian erythropoiesis

Molecular cell, 2021-03, Vol.81 (5), p.998-1012.e7

2021

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α-Globin as a molecular target in the treatment of β-thalassemia

Blood, 2015-06, Vol.125 (24), p.3694-3701

2015

Volltextzugriff (PDF)

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene

Human gene therapy, 2016-02, Vol.27 (2), p.148

2016

Volltextzugriff (PDF)

Challenges of blood transfusions in β-thalassemia

Blood reviews, 2019-09, Vol.37, p.100588-100588, Article 100588

2019

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Correction of β-thalassemia mutant by base editor in human embryos

Protein & cell, 2017-11, Vol.8 (11), p.811-822

2017

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Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

Cell, 2018-04, Vol.173 (2), p.430-442.e17

2018

Volltextzugriff (PDF)

Therapeutic base editing of human hematopoietic stem cells

Nature medicine, 2020-04, Vol.26 (4), p.535-541

2020

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Iron metabolism under conditions of ineffective erythropoiesis in β-thalassemia

Blood, 2019-01, Vol.133 (1), p.51-58

Rivella, Stefano

2019

Volltextzugriff (PDF)

Identification of erythroferrone as an erythroid regulator of iron metabolism

Nature genetics, 2014-07, Vol.46 (7), p.678-684

2014

Volltextzugriff (PDF)

In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia

The Journal of clinical investigation, 2019-02, Vol.129 (2), p.598-615

2019

Volltextzugriff (PDF)

Gene Therapy for β-Hemoglobinopathies

Molecular therapy, 2017-05, Vol.25 (5), p.1142-1154

2017

Volltextzugriff (PDF)

Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin

Current opinion in genetics & development, 2015-08, Vol.33, p.62-70

2015

Volltextzugriff (PDF)

DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia

Clinical chemistry (Baltimore, Md.), 2017-10, Vol.63 (10), p.1614-1623

2017

Volltextzugriff (PDF)

Effects of erythropoietin on fibroblast growth factor 23 in mice and humans

Nephrology, dialysis, transplantation, 2019-12, Vol.34 (12), p.2057-2065

2019

Volltextzugriff (PDF)

Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis

Blood, 2013-02, Vol.121 (8), p.e43-e49

2013

Volltextzugriff (PDF)

Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model

Blood, 2018-11, Vol.132 (21), p.2286-2297

2018

Volltextzugriff (PDF)

β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

Blood, 2011-10, Vol.118 (16), p.4321-4330

2011

Volltextzugriff (PDF)

Transcription Activator-like Effector Nuclease (TALEN)-mediated Gene Correction in Integration-free β-Thalassemia Induced Pluripotent Stem Cells

The Journal of biological chemistry, 2013-11, Vol.288 (48), p.34671-34679

2013

Volltextzugriff (PDF)

Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis

Blood, 2012-05, Vol.119 (22), p.5276-5284

2012

Volltextzugriff (PDF)

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model

Blood, 2018-01, Vol.131 (2), p.236-246

2018

Volltextzugriff (PDF)

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HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia

Non-transferrin-bound iron transporters

Hepcidin agonists as therapeutic tools

Genome editing using CRISPR-Cas9 to create the HPFH genotype in HSPCs: An approach for treating sickle cell disease and β-thalassemia

Co-transcriptional splicing regulates 3′ end cleavage during mammalian erythropoiesis

α-Globin as a molecular target in the treatment of β-thalassemia

Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene

Challenges of blood transfusions in β-thalassemia

Correction of β-thalassemia mutant by base editor in human embryos

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

Therapeutic base editing of human hematopoietic stem cells

Iron metabolism under conditions of ineffective erythropoiesis in β-thalassemia

Identification of erythroferrone as an erythroid regulator of iron metabolism

In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia

Gene Therapy for β-Hemoglobinopathies

Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin

DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia

Effects of erythropoietin on fibroblast growth factor 23 in mice and humans

Quantitative analysis of murine terminal erythroid differentiation in vivo: novel method to study normal and disordered erythropoiesis

Transferrin receptor 2 is a potential novel therapeutic target for β-thalassemia: evidence from a murine model

β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

Transcription Activator-like Effector Nuclease (TALEN)-mediated Gene Correction in Integration-free β-Thalassemia Induced Pluripotent Stem Cells

Heme-regulated eIF2α kinase activated Atf4 signaling pathway in oxidative stress and erythropoiesis

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model

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