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Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure

Nature medicine, 2007-03, Vol.13 (3), p.315-323

2007

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Pasireotide and Octreotide Stimulate Distinct Patterns of sst2A Somatostatin Receptor Phosphorylation

Molecular endocrinology (Baltimore, Md.), 2010-02, Vol.24 (2), p.436-446

2010

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Regulatory mechanisms underlying GKR2 levels in U937 cells: Evidence for GRK3 involvement

Biochemical pharmacology, 2007-06, Vol.73 (11), p.1758-1767

2007

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Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2

Cell, 2007-05, Vol.129 (3), p.511-522

2007

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GRK2 Negatively Regulates Glycogen Synthesis in Mouse Liver FL83B Cells

The Journal of biological chemistry, 2007-07, Vol.282 (28), p.20612-20620

2007

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Substrate Specificities of G Protein-Coupled Receptor Kinase-2 and -3 at Cardiac Myocyte Receptors Provide Basis for Distinct Roles in Regulation of Myocardial Function

Molecular pharmacology, 2007-09, Vol.72 (3), p.582-591

2007

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Cardiac-Specific Ablation of G-Protein Receptor Kinase 2 Redefines Its Roles in Heart Development and β-Adrenergic Signaling

Circulation research, 2006-10, Vol.99 (9), p.996-1003

2006

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Smoothened Signal Transduction Is Promoted by G Protein-Coupled Receptor Kinase 2

Molecular and Cellular Biology, 2006-10, Vol.26 (20), p.7550-7560

2006

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G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton

Molecular biology of the cell, 2005-07, Vol.16 (7), p.3088-3099

2005

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β Adrenergic Receptor Kinase C-Terminal Peptide Gene-Therapy Improves β2-Adrenergic Receptor-Dependent Neoangiogenesis after Hindlimb Ischemia

The Journal of pharmacology and experimental therapeutics, 2016-02, Vol.356 (2), p.503

2016

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Taking the heart failure battle inside the cell: Small molecule targeting of Gβγ subunits

Journal of molecular and cellular cardiology, 2011-10, Vol.51 (4), p.462-467

2011

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G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits

Molecular biology of the cell, 2006-01, Vol.17 (1), p.25-31

2006

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AAV6-βARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve

The Journal of thoracic and cardiovascular surgery, 2012-03, Vol.143 (3), p.720-726.e3

2012

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Mu Opioid Receptor Activation of ERK1/2 Is GRK3 and Arrestin Dependent in Striatal Neurons

The Journal of biological chemistry, 2006-11, Vol.281 (45), p.34515-34524

2006

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Functional Desensitization of the Extracellular Calcium-Sensing Receptor Is Regulated via Distinct Mechanisms: Role of G Protein-Coupled Receptor Kinases, Protein Kinase C and β-Arrestins

Endocrinology (Philadelphia), 2007-05, Vol.148 (5), p.2398-2404

2007

Volltextzugriff (PDF)

Cooperative Regulation of p70S6 Kinase by Receptor Tyrosine Kinases and G Protein-Coupled Receptors Augments Airway Smooth Muscle Growth

Biochemistry (Easton), 2005-11, Vol.44 (44), p.14595-14605

2005

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G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (19), p.7963-7968

2007

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Gender differences in β-adrenoceptor system in cardiac hypertrophy due to arteriovenous fistula

Journal of cellular physiology, 2011-01, Vol.226 (1), p.181-186

2011

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Knock-out Mice Reveal the Contributions of P2Y and P2X Receptors to Nucleotide-induced Ca2+ Signaling in Macrophages

The Journal of biological chemistry, 2006-11, Vol.281 (46), p.35147-35155

2006

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Receptor regulation in neuroendocrine–immune communication: Current knowledge and future perspectives

Brain, behavior, and immunity, 2007-01, Vol.21 (1), p.1-8

Heijnen, Cobi J

2007

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Targeting Myocardial β-Adrenergic Receptor Signaling and Calcium Cycling for Heart Failure Gene Therapy

Journal of cardiac failure, 2007-06, Vol.13 (5), p.401-414

2007

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Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions

Neurotoxicity research, 2006-08, Vol.10 (1), p.43-56

2006

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Phosphorylation of the Endogenous Thyrotropin-releasing Hormone Receptor in Pituitary GH3 Cells and Pituitary Tissue Revealed by Phosphosite-specific Antibodies

The Journal of biological chemistry, 2007-04, Vol.282 (17), p.12893-12906

2007

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The Membrane-proximal Portion of CD3 ε Associates with the Serine/Threonine Kinase GRK2

The Journal of biological chemistry, 2007-06, Vol.282 (22), p.16126-16134

2007

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G-protein-coupled receptor kinase activity in human heart failure : Effects of β-adrenoceptor blockade

Cardiovascular research, 2005-06, Vol.66 (3), p.512-519

2005

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Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure

Pasireotide and Octreotide Stimulate Distinct Patterns of sst2A Somatostatin Receptor Phosphorylation

Regulatory mechanisms underlying GKR2 levels in U937 cells: Evidence for GRK3 involvement

Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2

GRK2 Negatively Regulates Glycogen Synthesis in Mouse Liver FL83B Cells

Substrate Specificities of G Protein-Coupled Receptor Kinase-2 and -3 at Cardiac Myocyte Receptors Provide Basis for Distinct Roles in Regulation of Myocardial Function

Cardiac-Specific Ablation of G-Protein Receptor Kinase 2 Redefines Its Roles in Heart Development and β-Adrenergic Signaling

Smoothened Signal Transduction Is Promoted by G Protein-Coupled Receptor Kinase 2

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton

β Adrenergic Receptor Kinase C-Terminal Peptide Gene-Therapy Improves β2-Adrenergic Receptor-Dependent Neoangiogenesis after Hindlimb Ischemia

Taking the heart failure battle inside the cell: Small molecule targeting of Gβγ subunits

G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits

AAV6-βARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve

Mu Opioid Receptor Activation of ERK1/2 Is GRK3 and Arrestin Dependent in Striatal Neurons

Functional Desensitization of the Extracellular Calcium-Sensing Receptor Is Regulated via Distinct Mechanisms: Role of G Protein-Coupled Receptor Kinases, Protein Kinase C and β-Arrestins

Cooperative Regulation of p70S6 Kinase by Receptor Tyrosine Kinases and G Protein-Coupled Receptors Augments Airway Smooth Muscle Growth

G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila

Gender differences in β-adrenoceptor system in cardiac hypertrophy due to arteriovenous fistula

Knock-out Mice Reveal the Contributions of P2Y and P2X Receptors to Nucleotide-induced Ca2+ Signaling in Macrophages

Receptor regulation in neuroendocrine–immune communication: Current knowledge and future perspectives

Targeting Myocardial β-Adrenergic Receptor Signaling and Calcium Cycling for Heart Failure Gene Therapy

Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions

Phosphorylation of the Endogenous Thyrotropin-releasing Hormone Receptor in Pituitary GH3 Cells and Pituitary Tissue Revealed by Phosphosite-specific Antibodies

The Membrane-proximal Portion of CD3 ε Associates with the Serine/Threonine Kinase GRK2

G-protein-coupled receptor kinase activity in human heart failure : Effects of β-adrenoceptor blockade

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