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Updated Efficacy and Safety Data and Impact of the EML4-ALK Fusion Variant on the Efficacy of Alectinib in Untreated ALK-Positive Advanced Non–Small Cell Lung Cancer in the Global Phase III ALEX Study

Journal of thoracic oncology, 2019-07, Vol.14 (7), p.1233-1243

2019

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Alectinib Versus Crizotinib in Asian Patients With Treatment-Naïve Advanced ALK-Positive NSCLC: Five-Year Update From the Phase 3 ALESIA Study

JTO clinical and research reports, 2024-09, Vol.5 (9), p.100700, Article 100700

2024

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Patient-reported outcomes from the randomized phase III ALEX study of alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer

Lung cancer (Amsterdam, Netherlands), 2019-12, Vol.138, p.79-87

2019

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Updated overall survival and final progression-free survival data for patients with treatment-naive advanced ALK-positive non-small-cell lung cancer in the ALEX study

Annals of oncology, 2020-08, Vol.31 (8), p.1056-1064

2020

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Clinically Relevant Concentrations of Anticancer Drugs: A Guide for Nonclinical Studies

Clinical cancer research, 2017-07, Vol.23 (14), p.3489-3498

2017

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Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach

Oncotarget, 2021-02, Vol.12 (4), p.316-332

2021

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Phase II, Open-label, Single-arm, Multicenter Study to Assess the Activity and Safety of Alectinib as Neoadjuvant Treatment in Surgically Resectable Stage III ALK-positive NSCLC: ALNEO Trial

Clinical lung cancer, 2021-09, Vol.22 (5), p.473-477

2021

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Enhanced antitumor effect of alectinib in combination with cyclin-dependent kinase 4/6 inhibitor against RET-fusion-positive non-small cell lung cancer cells

Cancer biology & therapy, 2020-09, Vol.21 (9), p.863-870

2020

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Systematic review and meta-analysis of selected toxicities of approved ALK inhibitors in metastatic non-small cell lung cancer

Oncotarget, 2018-04, Vol.9 (31), p.22137-22146

2018

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Alectinib-induced Hemolytic Anemia with Positive Direct Antiglobulin Test in a Patient with Lung Adenocarcinoma: A Possible Drug-Drug Interaction Effect

Internal Medicine, 2023, pp.1286-22

2023

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The likelihood of being helped or harmed as a patient-centred tool to assess ALK-Inhibitors clinical impact and safety in ALK-addicted non-small cell lung cancer: A systematic review and sensitivity-analysis

Cancer treatment and research communications, 2024, Vol.41, p.100842, Article 100842

2024

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Oral Absorption from Surfactant-Based Drug Formulations: The Impact of Molecularly Dissolved Drug on Bioavailability

Journal of pharmaceutical sciences, 2024-07

2024

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Opportunities and challenges in using real-world data for health care

The Journal of clinical investigation, 2020-02, Vol.130 (2), p.565-574

2020

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Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001-2020)

Journal of hematology and oncology, 2020-10, Vol.13 (1), p.143-143, Article 143

2020

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Tree-in-bud Pattern in ALK-positive Lung Adenocarcinoma

Internal Medicine, 2020, pp.4076-19

2020

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VATS right upper lobectomy after alectinib administration for ALK-positive lung adenocarcinoma

The Journal of the Japanese Association for Chest Surgery, 2021/05/15, Vol.35(4), pp.297-302

2021

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Rapid Acquisition of Alectinib Resistance in ALK-Positive Lung Cancer With High Tumor Mutation Burden

Journal of thoracic oncology, 2019-11, Vol.14 (11), p.2009-2018

2019

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Alectinib versus chemotherapy in crizotinib-pretreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer: results from the phase III ALUR study

Annals of oncology, 2018-06, Vol.29 (6), p.1409-1416

2018

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Severe Skin Toxicity Caused by Sequential Anti-PD-1 Antibody and Alectinib in Non-small-cell Lung Cancer: A Report of Two Cases and a Literature Review

Internal Medicine, 2022, pp.7472-21

2022

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Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib

European journal of medicinal chemistry, 2021-05, Vol.217, p.113335, Article 113335

2021

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First Case Report of Pregnancy on Alectinib in a Woman With Metastatic ALK-Rearranged Lung Cancer: A Case Report

Journal of thoracic oncology, 2021-05, Vol.16 (5), p.873-877

2021

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Alectinib versus crizotinib in treatment-naive anaplastic lymphoma kinase-positive (ALK+) non-small-cell lung cancer: CNS efficacy results from the ALEX study

Annals of oncology, 2018-11, Vol.29 (11), p.2214-2222

2018

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Changes in Red Cell Morphology and Haematological Laboratory Parameters Associated With Alectinib

Journal of clinical laboratory analysis, 2024-07, Vol.38 (13-14), p.e25089-n/a

2024

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Complete pathologic response to short-course neoadjuvant alectinib in mediastinal node positive (N2) ALK rearranged lung cancer

Lung cancer (Amsterdam, Netherlands), 2022-10, Vol.172, p.124-126

2022

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Updated Efficacy and Safety Data and Impact of the EML4-ALK Fusion Variant on the Efficacy of Alectinib in Untreated ALK-Positive Advanced Non–Small Cell Lung Cancer in the Global Phase III ALEX Study

Alectinib Versus Crizotinib in Asian Patients With Treatment-Naïve Advanced ALK-Positive NSCLC: Five-Year Update From the Phase 3 ALESIA Study

Patient-reported outcomes from the randomized phase III ALEX study of alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer

Updated overall survival and final progression-free survival data for patients with treatment-naive advanced ALK-positive non-small-cell lung cancer in the ALEX study

Clinically Relevant Concentrations of Anticancer Drugs: A Guide for Nonclinical Studies

Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach

Phase II, Open-label, Single-arm, Multicenter Study to Assess the Activity and Safety of Alectinib as Neoadjuvant Treatment in Surgically Resectable Stage III ALK-positive NSCLC: ALNEO Trial

Enhanced antitumor effect of alectinib in combination with cyclin-dependent kinase 4/6 inhibitor against RET-fusion-positive non-small cell lung cancer cells

Systematic review and meta-analysis of selected toxicities of approved ALK inhibitors in metastatic non-small cell lung cancer

Alectinib-induced Hemolytic Anemia with Positive Direct Antiglobulin Test in a Patient with Lung Adenocarcinoma: A Possible Drug-Drug Interaction Effect

The likelihood of being helped or harmed as a patient-centred tool to assess ALK-Inhibitors clinical impact and safety in ALK-addicted non-small cell lung cancer: A systematic review and sensitivity-analysis

Symptomatic androgen deficiency and sexual dysfunctions in male patients receiving alectinib for ALK-positive advanced nonsmall cell lung cancer

Oral Absorption from Surfactant-Based Drug Formulations: The Impact of Molecularly Dissolved Drug on Bioavailability

Opportunities and challenges in using real-world data for health care

Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001-2020)

Tree-in-bud Pattern in ALK-positive Lung Adenocarcinoma

VATS right upper lobectomy after alectinib administration for ALK-positive lung adenocarcinoma

Rapid Acquisition of Alectinib Resistance in ALK-Positive Lung Cancer With High Tumor Mutation Burden

Alectinib versus chemotherapy in crizotinib-pretreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer: results from the phase III ALUR study

Severe Skin Toxicity Caused by Sequential Anti-PD-1 Antibody and Alectinib in Non-small-cell Lung Cancer: A Report of Two Cases and a Literature Review

Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib

First Case Report of Pregnancy on Alectinib in a Woman With Metastatic ALK-Rearranged Lung Cancer: A Case Report

Alectinib versus crizotinib in treatment-naive anaplastic lymphoma kinase-positive (ALK+) non-small-cell lung cancer: CNS efficacy results from the ALEX study

Changes in Red Cell Morphology and Haematological Laboratory Parameters Associated With Alectinib

Complete pathologic response to short-course neoadjuvant alectinib in mediastinal node positive (N2) ALK rearranged lung cancer

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