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Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors

Journal of clinical oncology, 2012-11, Vol.30 (32), p.4011-4016

2012

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Improving Biopharmaceutical Properties of Vinpocetine Through Cocrystallization

Journal of pharmaceutical sciences, 2016-12, Vol.105 (12), p.3626-3633

2016

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Rapid and simultaneous determination of five vinca alkaloids in Catharanthus roseus and human serum using trilinear component modeling of liquid chromatography–diode array detection data

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-07, Vol.1026, p.114-123

2016

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Optimized preparation of vinpocetine proliposomes by a novel method and in vivo evaluation of its pharmacokinetics in New Zealand rabbits

Journal of controlled release, 2009-11, Vol.140 (1), p.61-68

2009

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Clinical Pharmacokinetics and Exposure-Toxicity Relationship of a Folate-Vinca Alkaloid Conjugate EC145 in Cancer Patients

Journal of clinical pharmacology, 2009-12, Vol.49 (12), p.1467-1476

2009

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Liquid chromatography mass spectrometry simultaneous determination of vindoline and catharanthine in rat plasma and its application to a pharmacokinetic study

Biomedical chromatography, 2015-01, Vol.29 (1), p.97-102

2015

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Multidisciplinary Approach on Characterizing a Mechanochemically Activated Composite of Vinpocetine and Crospovidone

Journal of pharmaceutical sciences, 2011-03, Vol.100 (3), p.915-932

2011

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Determination of vinpocetine and its primary metabolite, apovincaminic acid, in rat plasma by liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-07, Vol.878 (22), p.1959-1966

2010

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Cyclodextrin Multicomponent Complexation and Controlled Release Delivery Strategies to Optimize the Oral Bioavailability of Vinpocetine

Journal of pharmaceutical sciences, 2007-08, Vol.96 (8), p.2018-2028

2007

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Selective reduction of N-oxides to amines: application to drug metabolism

Drug metabolism and disposition, 2004-09, Vol.32 (9), p.966

2004

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Validated liquid chromatography mass spectrometry method for quantitative determination of strictosamide in dog plasma and its application to pharmacokinetic study

Biomedical chromatography, 2011-12, Vol.25 (12), p.1338-1342

2011

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In vitro and in vivo studies on the complexes of vinpocetine with hydroxypropyl-beta-cyclodextrin

Archives of pharmacal research, 2007-08, Vol.30 (8), p.991-1001

2007

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PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects

Acta neurologica Scandinavica, 2002-12, Vol.106 (6), p.325-332

2002

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Determination of apovincaminic acid in human plasma by high-performance liquid chromatography using solid-phase extraction and ultraviolet detection

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-01, Vol.830 (2), p.201-206

2006

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New HPLC-MS method for quantitative determination of apovincaminic acid in human plasma

Journal of separation science, 2006-02, Vol.29 (3), p.385-389

2006

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Brain Uptake and Plasma Metabolism of [11C]Vinpocetine: A Preliminary PET Study in a Cynomolgus Monkey

Journal of neuroimaging, 1999-10, Vol.9 (4), p.217-222

1999

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Human positron emission tomography with oral 11C-vinpocetine

Orvosi hetilap, 2003-11, Vol.144 (46), p.2271

2003

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Determination of vinca alkaloids in human plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry

Cancer chemotherapy and pharmacology, 1997, Vol.39 (4), p.286-290

1997

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Determination of apovincaminic acid in human plasma by high-performance liquid chromatography

Journal of pharmaceutical and biomedical analysis, 1996-03, Vol.14 (5), p.617-622

1996

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Slow infusion of vinca alkaloids in the treatment of idiopathic thrombocytopenic purpura

Annals of internal medicine, 1984-02, Vol.100 (2), p.192

1984

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Lack of pharmacokinetic interaction between vinpocetine and oxazepam

British journal of clinical pharmacology, 1994-08, Vol.38 (2), p.143-146

1994

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High-performance liquid chromatographic determination of vinca-alkaloids in plasma and urine

Journal of chromatography, 1985, Vol.345 (2), p.309-321

1985

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Binding of a new vinca alkaloid derivative, S12363, to human plasma proteins and platelets. Usefulness of an erythrocyte partitioning technique

Investigational new drugs, 1992-11, Vol.10 (4), p.263-268

1992

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In vitro-in vivo correlation of the pharmacokinetics of vinpocetine

Polish journal of pharmacology, 2001-11, Vol.53 (6), p.623

2001

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Pharmacokinetics of vinpocetine and its main metabolite apovincaminic acid before and after the chronic oral administration of vinpocetine to humans

European journal of drug metabolism and pharmacokinetics, 1990, Vol.15 (1), p.1-5

1990

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Phase I Study of Folate Conjugate EC145 (Vintafolide) in Patients With Refractory Solid Tumors

Improving Biopharmaceutical Properties of Vinpocetine Through Cocrystallization

Rapid and simultaneous determination of five vinca alkaloids in Catharanthus roseus and human serum using trilinear component modeling of liquid chromatography–diode array detection data

Optimized preparation of vinpocetine proliposomes by a novel method and in vivo evaluation of its pharmacokinetics in New Zealand rabbits

Clinical Pharmacokinetics and Exposure-Toxicity Relationship of a Folate-Vinca Alkaloid Conjugate EC145 in Cancer Patients

Liquid chromatography mass spectrometry simultaneous determination of vindoline and catharanthine in rat plasma and its application to a pharmacokinetic study

Multidisciplinary Approach on Characterizing a Mechanochemically Activated Composite of Vinpocetine and Crospovidone

Determination of vinpocetine and its primary metabolite, apovincaminic acid, in rat plasma by liquid chromatography–tandem mass spectrometry

Cyclodextrin Multicomponent Complexation and Controlled Release Delivery Strategies to Optimize the Oral Bioavailability of Vinpocetine

Selective reduction of N-oxides to amines: application to drug metabolism

Validated liquid chromatography mass spectrometry method for quantitative determination of strictosamide in dog plasma and its application to pharmacokinetic study

In vitro and in vivo studies on the complexes of vinpocetine with hydroxypropyl-beta-cyclodextrin

PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects

Determination of apovincaminic acid in human plasma by high-performance liquid chromatography using solid-phase extraction and ultraviolet detection

New HPLC-MS method for quantitative determination of apovincaminic acid in human plasma

Brain Uptake and Plasma Metabolism of [11C]Vinpocetine: A Preliminary PET Study in a Cynomolgus Monkey

Human positron emission tomography with oral 11C-vinpocetine

Determination of vinca alkaloids in human plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry

Determination of apovincaminic acid in human plasma by high-performance liquid chromatography

Slow infusion of vinca alkaloids in the treatment of idiopathic thrombocytopenic purpura

Lack of pharmacokinetic interaction between vinpocetine and oxazepam

High-performance liquid chromatographic determination of vinca-alkaloids in plasma and urine

Binding of a new vinca alkaloid derivative, S12363, to human plasma proteins and platelets. Usefulness of an erythrocyte partitioning technique

In vitro-in vivo correlation of the pharmacokinetics of vinpocetine

Pharmacokinetics of vinpocetine and its main metabolite apovincaminic acid before and after the chronic oral administration of vinpocetine to humans

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