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Preparation and Preliminary Structure–Activity Relationship Studies of Schwarzinicine A Analogs as Vasorelaxant Agents

Journal of natural products (Washington, D.C.), 2024-04, Vol.87 (4), p.675-691

2024

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[1, 2, 4]-oxadiazoles: synthesis and biological applications

Mini reviews in medicinal chemistry, 2014-04, Vol.14 (4), p.355

2014

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New flavonoid-based compound synthesis strategy for antihypertensive drug development

Life sciences (1973), 2020-05, Vol.249, p.117512-117512, Article 117512

2020

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Recent advances in targeting the prostacyclin pathway in pulmonary arterial hypertension

European respiratory review, 2015-12, Vol.24 (138), p.630-641

2015

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A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity

Journal of inorganic biochemistry, 2020-09, Vol.210, p.111133-111133, Article 111133

2020

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CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule

The FASEB journal, 2005-02, Vol.19 (2), p.284-286

2005

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Benzothiazole Sulfinate: a Water-Soluble and Slow-Releasing Sulfur Dioxide Donor

ACS chemical biology, 2016-06, Vol.11 (6), p.1647-1651

2016

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Design of PVP/VA S-630 based tadalafil solid dispersion to enhance the dissolution rate

European journal of pharmaceutical sciences, 2017-01, Vol.97, p.269-276

2017

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Novel rhynchophylline analogues as microvascular relaxation agents for the treatment of microvascular dysfunction caused by diabetes

European journal of medicinal chemistry, 2017-10, Vol.139, p.657-664

2017

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Synthesis, characterization and biological evaluation of benzothiazoles and tetrahydrobenzothiazoles bearing urea or thiourea moieties as vasorelaxants and inhibitors of the insulin releasing process

European journal of medicinal chemistry, 2016-06, Vol.115, p.352-360

2016

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The role of ancillary ligand substituents in the biological activity of triruthenium-NO complexes

Journal of inorganic biochemistry, 2018-09, Vol.186, p.197-205

2018

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Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives

European journal of medicinal chemistry, 2009-10, Vol.44 (10), p.4004-4009

2009

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Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives

European journal of medicinal chemistry, 2016-01, Vol.108, p.663-673

2016

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Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction

Scientific reports, 2017-10, Vol.7 (1), p.14326-10, Article 14326

2017

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Amino acid derivatives of ligustrazine-oleanolic acid as new cytotoxic agents

Molecules (Basel, Switzerland), 2014-11, Vol.19 (11), p.18215-18231

2014

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Design and Synthesis of Novel Xyloketal Derivatives and Their Vasorelaxing Activities in Rat Thoracic Aorta and Angiogenic Activities in Zebrafish Angiogenesis Screen

Journal of medicinal chemistry, 2010-06, Vol.53 (12), p.4642-4653

2010

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Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin–NO Biochemistry

Biochemistry (Easton), 2015-12, Vol.54 (49), p.7178-7192

2015

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Synthesis of 4-aryl-3,4-dihydropyrimidin-2(1 H)-thione derivatives as potential calcium channel blockers

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (24), p.8582-8589

2006

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14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates Containing Epoxide Bioisosteres: Influence upon Vascular Relaxation and Soluble Epoxide Hydrolase Inhibition

Journal of medicinal chemistry, 2009-08, Vol.52 (16), p.5069-5075

2009

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In vitro study and structure-activity relationship analysis of stilbenoid derivatives as powerful vasorelaxants: Discovery of new lead compound

Bioorganic chemistry, 2020-11, Vol.104, p.104239, Article 104239

2020

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Synthesis and biological evaluation of Vinpocetine derivatives

Bioorganic & medicinal chemistry letters, 2020-01, Vol.30 (2), p.126472-126472, Article 126472

2020

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Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators

Molecules (Basel, Switzerland), 2017-10, Vol.22 (11), p.1820

2017

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Synthesis and vasodilator effects of rutaecarpine analogues which might be involved transient receptor potential vanilloid subfamily, member 1 (TRPV1)

Bioorganic & medicinal chemistry, 2009-03, Vol.17 (6), p.2351-2359

2009

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Indolo[3,2-b]quinolines: synthesis, biological evaluation and structure activity-relationships

Mini reviews in medicinal chemistry, 2008-06, Vol.8 (6), p.538

2008

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Design and Synthesis of Small Molecule RhoA Inhibitors: A New Promising Therapy for Cardiovascular Diseases?

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4508-4522

2011

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Preparation and Preliminary Structure–Activity Relationship Studies of Schwarzinicine A Analogs as Vasorelaxant Agents

[1, 2, 4]-oxadiazoles: synthesis and biological applications

New flavonoid-based compound synthesis strategy for antihypertensive drug development

Recent advances in targeting the prostacyclin pathway in pulmonary arterial hypertension

A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity

CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule

Benzothiazole Sulfinate: a Water-Soluble and Slow-Releasing Sulfur Dioxide Donor

Design of PVP/VA S-630 based tadalafil solid dispersion to enhance the dissolution rate

Novel rhynchophylline analogues as microvascular relaxation agents for the treatment of microvascular dysfunction caused by diabetes

Synthesis, characterization and biological evaluation of benzothiazoles and tetrahydrobenzothiazoles bearing urea or thiourea moieties as vasorelaxants and inhibitors of the insulin releasing process

The role of ancillary ligand substituents in the biological activity of triruthenium-NO complexes

Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives

Synthesis, vasorelaxant activity and 2D-QSAR study of some novel pyridazine derivatives

Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction

Amino acid derivatives of ligustrazine-oleanolic acid as new cytotoxic agents

Design and Synthesis of Novel Xyloketal Derivatives and Their Vasorelaxing Activities in Rat Thoracic Aorta and Angiogenic Activities in Zebrafish Angiogenesis Screen

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin–NO Biochemistry

Synthesis of 4-aryl-3,4-dihydropyrimidin-2(1 H)-thione derivatives as potential calcium channel blockers

14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates Containing Epoxide Bioisosteres: Influence upon Vascular Relaxation and Soluble Epoxide Hydrolase Inhibition

In vitro study and structure-activity relationship analysis of stilbenoid derivatives as powerful vasorelaxants: Discovery of new lead compound

Synthesis and biological evaluation of Vinpocetine derivatives

Synthesis and 2D-QSAR Study of Active Benzofuran-Based Vasodilators

Synthesis and vasodilator effects of rutaecarpine analogues which might be involved transient receptor potential vanilloid subfamily, member 1 (TRPV1)

Indolo[3,2-b]quinolines: synthesis, biological evaluation and structure activity-relationships

Design and Synthesis of Small Molecule RhoA Inhibitors: A New Promising Therapy for Cardiovascular Diseases?

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