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An investigation into the origin of the biased agonism associated with the urotensin II receptor activation

Journal of peptide science, 2015-05, Vol.21 (5), p.392-399

2015

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The Role of Urotensin Receptors in the Paracetamol‐Induced Hepatotoxicity Model in Mice: Ameliorative Potential of Urotensin II Antagonist

Basic & clinical pharmacology & toxicology, 2016-02, Vol.118 (2), p.150-159

2016

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Urotensin II Stimulates Vascular Endothelial Growth Factor Secretion From Adventitial Fibroblasts in Synergy With Angiotensin II

Circulation Journal, 2012, Vol.76(5), pp.1267-1273

2012

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Human urotensin-II as a novel cardiovascular target: ‘heart’ of the matter or simply a fishy ‘tail’?

Current opinion in pharmacology, 2003-04, Vol.3 (2), p.159-167

Douglas, Stephen A

2003

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Structure-Function Analysis of Urotensin II and Its Use in the Construction of a Ligand-Receptor Working Model

Angewandte Chemie International Edition, 2002-08, Vol.41 (16), p.2940-2944

2002

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Urotensin-II and the cardiovascular system - the importance of developing modulators

Expert opinion on investigational drugs, 2004-05, Vol.13 (5), p.479-487

Doggrell, Sheila A

2004

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Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites

Biochemical journal, 2007-02, Vol.402 (1), p.51-61

2007

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Design and Synthesis of Potent Cystine-Free Cyclic Hexapeptide Agonists at the Human Urotensin Receptor

Organic letters, 2006-04, Vol.8 (9), p.1799-1802

2006

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Urotensin-II receptor peptide agonists

Medicinal research reviews, 2004-09, Vol.24 (5), p.577-588

2004

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Facile preparation of disulfide-bridged peptides using the polymer-supported oxidant CLEAR-OX

The journal of peptide research, 2004-03, Vol.63 (3), p.303

2004

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Monitor – Molecules

Drug discovery today, 2006-02, Vol.11 (3-4), p.181-181

Edwards, Paul

2006

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Development of therapeutic agents related to urotensin II

Nihon rinshō, 2004-09, Vol.62 Suppl 9, p.741

Mori, Masaaki

2004

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Identification of new agonists of urotensin-II from a cyclic peptide library

Bioorganic & medicinal chemistry, 2009-09, Vol.17 (18), p.6742-6747

2009

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Functional Selectivity Revealed by N‑Methylation Scanning of Human Urotensin II and Related Peptides

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1455-1467

2019

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Expanding Structure–Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N‑Terminal Region for Novel Urotensin II Receptor Modulators

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.13879-13890

2024

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Combination of Docking-Based and Pharmacophore-Based Virtual Screening Identifies Novel Agonists That Target the Urotensin Receptor

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8692

2022

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Urotensin receptors as a new target for CLP induced septic lung injury in mice

Naunyn-Schmiedeberg's archives of pharmacology, 2019-02, Vol.392 (2), p.135-145

2019

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Blocking of urotensin receptors as new target for treatment of carrageenan induced inflammation in rats

Peptides (New York, N.Y. : 1980), 2016-08, Vol.82, p.35-43

2016

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Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

Nature (London), 1999-09, Vol.401 (6750), p.282-286

1999

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Urocontrin, a novel UT receptor ligand with a unique pharmacological profile

Biochemical pharmacology, 2012-03, Vol.83 (5), p.608-615

2012

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Structure-Activity Study of the Peptides P5U and Urantide by the Development of Analogues Containing Uncoded Amino Acids at Position 9

ChemMedChem, 2016-08, Vol.11 (16), p.1856-1864

2016

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Urotensin-II Receptor Modulators as Potential Drugs

Journal of medicinal chemistry, 2010-04, Vol.53 (7), p.2695-2708

2010

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New insight into the binding mode of peptides at urotensin-II receptor by Trp-constrained analogues of P5U and urantide

Journal of peptide science, 2013-05, Vol.19 (5), p.293-300

2013

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Urotensin II and urotensin II-related peptide activate somatostatin receptor subtypes 2 and 5

Peptides (New York, N.Y. : 1980), 2008-05, Vol.29 (5), p.711-720

2008

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Assessment of sensorimotor gating following selective lesions of cholinergic pedunculopontine neurons

The European journal of neuroscience, 2014-11, Vol.40 (10), p.3526-3537

2014

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An investigation into the origin of the biased agonism associated with the urotensin II receptor activation

The Role of Urotensin Receptors in the Paracetamol‐Induced Hepatotoxicity Model in Mice: Ameliorative Potential of Urotensin II Antagonist

Urotensin II Stimulates Vascular Endothelial Growth Factor Secretion From Adventitial Fibroblasts in Synergy With Angiotensin II

Human urotensin-II as a novel cardiovascular target: ‘heart’ of the matter or simply a fishy ‘tail’?

Structure-Function Analysis of Urotensin II and Its Use in the Construction of a Ligand-Receptor Working Model

Urotensin-II and the cardiovascular system - the importance of developing modulators

Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites

Design and Synthesis of Potent Cystine-Free Cyclic Hexapeptide Agonists at the Human Urotensin Receptor

Urotensin-II receptor peptide agonists

Facile preparation of disulfide-bridged peptides using the polymer-supported oxidant CLEAR-OX

Monitor – Molecules

Development of therapeutic agents related to urotensin II

Identification of new agonists of urotensin-II from a cyclic peptide library

Functional Selectivity Revealed by N‑Methylation Scanning of Human Urotensin II and Related Peptides

Expanding Structure–Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N‑Terminal Region for Novel Urotensin II Receptor Modulators

Combination of Docking-Based and Pharmacophore-Based Virtual Screening Identifies Novel Agonists That Target the Urotensin Receptor

Urotensin receptors as a new target for CLP induced septic lung injury in mice

Blocking of urotensin receptors as new target for treatment of carrageenan induced inflammation in rats

Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14

Urocontrin, a novel UT receptor ligand with a unique pharmacological profile

Structure-Activity Study of the Peptides P5U and Urantide by the Development of Analogues Containing Uncoded Amino Acids at Position 9

Urotensin-II Receptor Modulators as Potential Drugs

New insight into the binding mode of peptides at urotensin-II receptor by Trp-constrained analogues of P5U and urantide

Urotensin II and urotensin II-related peptide activate somatostatin receptor subtypes 2 and 5

Assessment of sensorimotor gating following selective lesions of cholinergic pedunculopontine neurons

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