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Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages

Annals of the rheumatic diseases, 2020-11, Vol.79 (11), p.1506-1514

2020

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TET2-mutant clonal hematopoiesis and risk of gout

Blood, 2022-09, Vol.140 (10), p.1094-1103

2022

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Soluble uric acid inhibits β2 integrin–mediated neutrophil recruitment in innate immunity

Blood, 2022-06, Vol.139 (23), p.3402-3417

2022

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Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats

The Journal of biological chemistry, 2019-03, Vol.294 (11), p.4272-4281

2019

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Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism

Journal of hepatology, 2016-04, Vol.64 (4), p.925-932

2016

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Nanomaterials-Based Nanosensors for the Simultaneous Electrochemical Determination of Biologically Important Compounds: Ascorbic Acid, Uric Acid, and Dopamine

Critical reviews in analytical chemistry, 2019-03, Vol.49 (2), p.101-125

2019

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Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial

Lancet neurology, 2014-05, Vol.13 (5), p.453-460

2014

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Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

Annals of the rheumatic diseases, 2016-04, Vol.75 (4), p.755-762

2016

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Uric Acid Is Associated With Inflammatory Biomarkers and Induces Inflammation Via Activating the NF-κB Signaling Pathway in HepG2 Cells

Arteriosclerosis, thrombosis, and vascular biology, 2017-06, Vol.37 (6), p.1241-1249

2017

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Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

Annals of the rheumatic diseases, 2016-03, Vol.75 (3), p.593-600

2016

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Gout-associated uric acid crystals activate the NALP3 inflammasome

Nature, 2006-03, Vol.440 (7081), p.237-241

2006

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Effects of Empagliflozin in Women and Men With Heart Failure and Preserved Ejection Fraction

Circulation (New York, N.Y.), 2022-10, Vol.146 (14), p.1046-1055

2022

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Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout

Annals of the rheumatic diseases, 2020-04, Vol.79 (4), p.536-544

2020

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Uric acid accumulation in the kidney triggers mast cell degranulation and aggravates renal oxidative stress

Toxicology (Amsterdam), 2023-01, Vol.483, p.153387, Article 153387

2023

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IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages

The FASEB journal, 2015-10, Vol.29 (10), p.4162-4173

2015

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Uric acid as a CNS antioxidant

Journal of Alzheimer's disease, 2010-01, Vol.19 (4), p.1331-1336

2010

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Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

The FASEB journal, 2019-01, Vol.33 (1), p.1401-1414

2019

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Uric acid promotes an acute inflammatory response to sterile cell death in mice

The Journal of clinical investigation, 2010-06, Vol.120 (6), p.1939-1949

2010

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Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice

Metabolism, clinical and experimental, 2017-09, Vol.74, p.32-40

2017

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Rutin ameliorates gout via reducing XOD activity, inhibiting ROS production and NLRP3 inflammasome activation in quail

Biomedicine & pharmacotherapy, 2023-02, Vol.158, p.114175-114175, Article 114175

2023

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Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

The EMBO journal, 2013-08, Vol.32 (17), p.2336-2347

2013

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Recombinant human proteoglycan-4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines in human and murine macrophages

Arthritis research & therapy, 2018-08, Vol.20 (1), p.192-192, Article 192

2018

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Uric Acid Induces a Proatherothrombotic Phenotype in Human Endothelial Cells by Imbalancing the Tissue Factor/Tissue Factor Pathway Inhibitor Pathway

Thrombosis and haemostasis, 2023-01, Vol.123 (1), p.64-75

2023

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Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin

Scientific reports, 2017-11, Vol.7 (1), p.15003-10, Article 15003

2017

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Theacrine and strictinin, two major ingredients for the anti-influenza activity of Yunnan Kucha tea

Journal of ethnopharmacology, 2020-11, Vol.262, p.113190-113190, Article 113190

2020

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Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages

TET2-mutant clonal hematopoiesis and risk of gout

Soluble uric acid inhibits β2 integrin–mediated neutrophil recruitment in innate immunity

Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats

Uric acid regulates hepatic steatosis and insulin resistance through the NLRP3 inflammasome-dependent mechanism

Nanomaterials-Based Nanosensors for the Simultaneous Electrochemical Determination of Biologically Important Compounds: Ascorbic Acid, Uric Acid, and Dopamine

Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial

Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra

Uric Acid Is Associated With Inflammatory Biomarkers and Induces Inflammation Via Activating the NF-κB Signaling Pathway in HepG2 Cells

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

Gout-associated uric acid crystals activate the NALP3 inflammasome

Effects of Empagliflozin in Women and Men With Heart Failure and Preserved Ejection Fraction

Rare genetic variants in interleukin-37 link this anti-inflammatory cytokine to the pathogenesis and treatment of gout

Uric acid accumulation in the kidney triggers mast cell degranulation and aggravates renal oxidative stress

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages

Uric acid as a CNS antioxidant

Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

Uric acid promotes an acute inflammatory response to sterile cell death in mice

Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice

Rutin ameliorates gout via reducing XOD activity, inhibiting ROS production and NLRP3 inflammasome activation in quail

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Recombinant human proteoglycan-4 reduces phagocytosis of urate crystals and downstream nuclear factor kappa B and inflammasome activation and production of cytokines and chemokines in human and murine macrophages

Uric Acid Induces a Proatherothrombotic Phenotype in Human Endothelial Cells by Imbalancing the Tissue Factor/Tissue Factor Pathway Inhibitor Pathway

Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin

Theacrine and strictinin, two major ingredients for the anti-influenza activity of Yunnan Kucha tea

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