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Preparation and antitrypanosomal activity of secochiliolide acid derivatives

Bioorganic & medicinal chemistry letters, 2013-09, Vol.23 (17), p.4964-4967

2013

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Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds

Bioorganic & medicinal chemistry letters, 2015-08, Vol.25 (16), p.3342-3345

2015

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Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound

European journal of medicinal chemistry, 2018-01, Vol.144, p.572-581

2018

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In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México

Bioorganic & medicinal chemistry, 2021-10, Vol.48, p.116417-116417, Article 116417

2021

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Synthesis of urea and thiourea derivatives of C20-epi-aminosalinomycin and their activity against Trypanosoma brucei

European journal of medicinal chemistry, 2023-03, Vol.250, p.115241-115241, Article 115241

2023

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Synthesis and evaluation of trypanocidal activity of derivatives of naturally occurring 2,5-diphenyloxazoles

Bioorganic & medicinal chemistry, 2021-07, Vol.42, p.116253-116253, Article 116253

2021

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Synthesis and trypanocidal activity of novel pyridinyl-1,3,4-thiadiazole derivatives

Biomedicine & pharmacotherapy, 2020-07, Vol.127, p.110162, Article 110162

2020

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In vitro trypanocidal activities and structure–activity relationships of ciprofloxacin analogs

Molecular diversity, 2024-08, Vol.28 (4), p.2667-2680

2024

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Unexpected rearrangement of ivermectin in the synthesis of new derivatives with trypanocidal and antiplasmodial activities

European journal of medicinal chemistry, 2024-01, Vol.263, p.115951-115951, Article 115951

2024

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Suramin: Effectiveness of analogues reveals structural features that are important for the potent trypanocidal activity of the drug

Experimental parasitology, 2024-05, Vol.260, p.108744-108744, Article 108744

2024

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Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity

European journal of medicinal chemistry, 2017-12, Vol.141, p.138-148

2017

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Green microalgae as a potential source of trypanocide compounds

Natural product research, 2024-07, Vol.38 (13), p.2329-2335

2024

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Gallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies

Molecules (Basel, Switzerland), 2022-09, Vol.27 (18), p.5876

2022

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Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi

Molecules (Basel, Switzerland), 2021-11, Vol.26 (21), p.6742

2021

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Synthesis by Microwave Irradiation, Molecular Structural Analysis and Trypanocidal Activity of Novel Pyrazole-tetrahydropyrimidine Derivatives

Current organic synthesis, 2023-01, Vol.20 (7), p.707-715

2023

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Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease

Current medicinal chemistry, 2017-05, Vol.24 (11), p.1066

2017

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Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against Trypanosoma cruzi

Molecules (Basel, Switzerland), 2021-01, Vol.26 (2), p.423

2021

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Bioactivity-guided isolation of trypanocidal coumarins and dihydro-pyranochromones from selected Apiaceae plant species

Phytochemistry (Oxford), 2023-09, Vol.213, p.113770-113770, Article 113770

2023

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Synthesis, in vitro and in vivo anti-Trypanosoma cruzi and toxicological activities of nitroaromatic Schiff bases

Biomedicine & pharmacotherapy, 2018-12, Vol.108, p.1703-1711

2018

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Synthesis, characterization and preliminary in vitro trypanocidal activity of N-arylfluorinated hydroxylated-Schiff bases

Journal of molecular structure, 2020-10, Vol.1218, p.128520, Article 128520

2020

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Improving in vitro screening compounds anti-Trypanosoma cruzi by GFP-expressing parasites

Memórias do Instituto Oswaldo Cruz, 2024-01, Vol.119, p.e230223-e230223

2024

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In vitro Trypanocidal Activity, Genomic Analysis of Isolates, and in vivo Transcription of Type VI Secretion System of Serratia marcescens Belonging to the Microbiota of Rhodnius prolixus Digestive Tract

Frontiers in microbiology, 2019-01, Vol.9, p.3205-3205

2019

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Synthesis and Evaluation of Nifurtimox–Adamantane Adducts with Trypanocidal Activity

ChemMedChem, 2019-07, Vol.14 (13), p.1227-1231

2019

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Asteraceae Plants as Sources of Compounds Against Leishmaniasis and Chagas Disease

Frontiers in pharmacology, 2019-05, Vol.10, p.477-477

2019

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Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies

Bioorganic & medicinal chemistry, 2021-01, Vol.29, p.115855-115855, Article 115855

2021

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Preparation and antitrypanosomal activity of secochiliolide acid derivatives

Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds

Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound

In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México

Synthesis of urea and thiourea derivatives of C20-epi-aminosalinomycin and their activity against Trypanosoma brucei

Synthesis and evaluation of trypanocidal activity of derivatives of naturally occurring 2,5-diphenyloxazoles

Synthesis and trypanocidal activity of novel pyridinyl-1,3,4-thiadiazole derivatives

In vitro trypanocidal activities and structure–activity relationships of ciprofloxacin analogs

Unexpected rearrangement of ivermectin in the synthesis of new derivatives with trypanocidal and antiplasmodial activities

Suramin: Effectiveness of analogues reveals structural features that are important for the potent trypanocidal activity of the drug

Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity

Green microalgae as a potential source of trypanocide compounds

Gallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies

Structural Optimization and Biological Activity of Pyrazole Derivatives: Virtual Computational Analysis, Recovery Assay and 3D Culture Model as Potential Predictive Tools of Effectiveness against Trypanosoma cruzi

Synthesis by Microwave Irradiation, Molecular Structural Analysis and Trypanocidal Activity of Novel Pyrazole-tetrahydropyrimidine Derivatives

Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease

Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against Trypanosoma cruzi

Bioactivity-guided isolation of trypanocidal coumarins and dihydro-pyranochromones from selected Apiaceae plant species

Synthesis, in vitro and in vivo anti-Trypanosoma cruzi and toxicological activities of nitroaromatic Schiff bases

Synthesis, characterization and preliminary in vitro trypanocidal activity of N-arylfluorinated hydroxylated-Schiff bases

Improving in vitro screening compounds anti-Trypanosoma cruzi by GFP-expressing parasites

In vitro Trypanocidal Activity, Genomic Analysis of Isolates, and in vivo Transcription of Type VI Secretion System of Serratia marcescens Belonging to the Microbiota of Rhodnius prolixus Digestive Tract

Synthesis and Evaluation of Nifurtimox–Adamantane Adducts with Trypanocidal Activity

Asteraceae Plants as Sources of Compounds Against Leishmaniasis and Chagas Disease

Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies

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