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A trimethoprim derivative impedes antibiotic resistance evolution

Nature communications, 2021-05, Vol.12 (1), p.2949-10, Article 2949

2021

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Occurrence and abundance of antibiotics and resistance genes in rivers, canal and near drug formulation facilities--a study in Pakistan

PloS one, 2013-06, Vol.8 (6), p.e62712

2013

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Selective concentrations for trimethoprim resistance in aquatic environments

Environment international, 2020-11, Vol.144, p.106083, Article 106083

2020

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Capture of a novel, antibiotic resistance encoding, mobile genetic element from Escherichia coli using a new entrapment vector

Journal of applied microbiology, 2021-03, Vol.130 (3), p.832-842

2021

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High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection

Molecular biology and evolution, 2019-07, Vol.36 (7), p.1533-1550

2019

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The BpeEF-OprC Efflux Pump Is Responsible for Widespread Trimethoprim Resistance in Clinical and Environmental Burkholderia pseudomallei Isolates

Antimicrobial Agents and Chemotherapy, 2013-09, Vol.57 (9), p.4381-4386

2013

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Holistic understanding of trimethoprim resistance in Streptococcus pneumoniae using an integrative approach of genome-wide association study, resistance reconstruction, and machine learning

mBio, 2024-09, Vol.15 (9), p.e0136024

2024

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Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei : Deviation from the Norm

mBio, 2017-09, Vol.8 (5)

2017

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Antimicrobial resistance in urinary pathogens and culture-independent detection of trimethoprim resistance in urine from patients with urinary tract infection

BMC microbiology, 2022-05, Vol.22 (1), p.144-144, Article 144

2022

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A novel method to determine antibiotic sensitivity in Bdellovibrio bacteriovorus reveals a DHFR-dependent natural trimethoprim resistance

Scientific reports, 2020-03, Vol.10 (1), p.5315-5315, Article 5315

2020

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Evolution of trimethoprim/sulfamethoxazole resistance in Shewanella algae from the perspective of comparative genomics and global phylogenic analysis

Journal of microbiology, immunology and infection, 2022-12, Vol.55 (6), p.1195-1202

2022

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Integron-Associated DfrB4, a Previously Uncharacterized Member of the Trimethoprim-Resistant Dihydrofolate Reductase B Family, Is a Clinically Identified Emergent Source of Antibiotic Resistance

Antimicrobial agents and chemotherapy, 2017-05, Vol.61 (5)

2017

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Pervasive gene deregulation underlies adaptation and maladaptation in trimethoprim-resistant E. coli

mBio, 2023-12, Vol.14 (6), p.e0211923

2023

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Correlation between the sulfamethoxazole-trimethoprim resistance of Shigella flexneri and the sul genes

Medicine (Baltimore), 2021-03, Vol.100 (10), p.e24970-e24970

2021

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Trimethoprim Resistance of Dihydrofolate Reductase Variants from Clinical Isolates of Pneumocystis jirovecii

Antimicrobial Agents and Chemotherapy, 2013-10, Vol.57 (10), p.4990-4998

2013

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Global emergence of trimethoprim/sulfamethoxazole resistance in Stenotrophomonas maltophilia mediated by acquisition of sul genes

Emerging infectious diseases, 2007-04, Vol.13 (4), p.559-565

2007

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Novel erm(T)-Carrying Multiresistance Plasmids from Porcine and Human Isolates of Methicillin-Resistant Staphylococcus aureus ST398 That Also Harbor Cadmium and Copper Resistance Determinants

Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3275-3282

2013

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Characterization of novel antibiotic resistance genes identified by functional metagenomics on soil samples

Environmental microbiology, 2011-04, Vol.13 (4), p.1101-1114

2011

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Construction of Mobilizable Mini-Tn7 Vectors for Bioluminescent Detection of Gram-Negative Bacteria and Single-Copy Promoter lux Reporter Analysis

Applied and Environmental Microbiology, 2013-07, Vol.79 (13), p.4149-4153

2013

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Prediction of antibiotic resistance from antibiotic resistance genes detected in antibiotic-resistant commensal Escherichia coli using PCR or WGS

Journal of antimicrobial chemotherapy, 2017-03, Vol.72 (3), p.700-704

2017

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Identification of a Novel Trimethoprim Resistance Gene, dfrK, in a Methicillin-Resistant Staphylococcus aureus ST398 Strain and Its Physical Linkage to the Tetracycline Resistance Gene tet(L)

Antimicrobial Agents and Chemotherapy, 2009-02, Vol.53 (2), p.776-778

2009

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Factors That Cause Trimethoprim Resistance in Streptococcus pyogenes

Antimicrobial agents and chemotherapy, 2014-04, Vol.58 (4), p.2281-2288

2014

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Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use

PloS one, 2010-02, Vol.5 (2), p.e9233-e9233

2010

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Clinical and microbiological characteristics of patients colonized or infected by Stenotrophomonas maltophilia : is resistance to sulfamethoxazole/trimethoprim a problem?

Revista do Instituto de Medicina Tropical de São Paulo, 2020-01, Vol.62, p.e96-7

2020

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Exploration into the origins and mobilization of di-hydrofolate reductase genes and the emergence of clinical resistance to trimethoprim

Microbial genomics, 2020-11, Vol.6 (11)

2020

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A trimethoprim derivative impedes antibiotic resistance evolution

Occurrence and abundance of antibiotics and resistance genes in rivers, canal and near drug formulation facilities--a study in Pakistan

Selective concentrations for trimethoprim resistance in aquatic environments

Capture of a novel, antibiotic resistance encoding, mobile genetic element from Escherichia coli using a new entrapment vector

High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection

The BpeEF-OprC Efflux Pump Is Responsible for Widespread Trimethoprim Resistance in Clinical and Environmental Burkholderia pseudomallei Isolates

Holistic understanding of trimethoprim resistance in Streptococcus pneumoniae using an integrative approach of genome-wide association study, resistance reconstruction, and machine learning

Mechanisms of Resistance to Folate Pathway Inhibitors in Burkholderia pseudomallei : Deviation from the Norm

Antimicrobial resistance in urinary pathogens and culture-independent detection of trimethoprim resistance in urine from patients with urinary tract infection

A novel method to determine antibiotic sensitivity in Bdellovibrio bacteriovorus reveals a DHFR-dependent natural trimethoprim resistance

Evolution of trimethoprim/sulfamethoxazole resistance in Shewanella algae from the perspective of comparative genomics and global phylogenic analysis

Integron-Associated DfrB4, a Previously Uncharacterized Member of the Trimethoprim-Resistant Dihydrofolate Reductase B Family, Is a Clinically Identified Emergent Source of Antibiotic Resistance

Pervasive gene deregulation underlies adaptation and maladaptation in trimethoprim-resistant E. coli

Correlation between the sulfamethoxazole-trimethoprim resistance of Shigella flexneri and the sul genes

Trimethoprim Resistance of Dihydrofolate Reductase Variants from Clinical Isolates of Pneumocystis jirovecii

Global emergence of trimethoprim/sulfamethoxazole resistance in Stenotrophomonas maltophilia mediated by acquisition of sul genes

Novel erm(T)-Carrying Multiresistance Plasmids from Porcine and Human Isolates of Methicillin-Resistant Staphylococcus aureus ST398 That Also Harbor Cadmium and Copper Resistance Determinants

Characterization of novel antibiotic resistance genes identified by functional metagenomics on soil samples

Construction of Mobilizable Mini-Tn7 Vectors for Bioluminescent Detection of Gram-Negative Bacteria and Single-Copy Promoter lux Reporter Analysis

Prediction of antibiotic resistance from antibiotic resistance genes detected in antibiotic-resistant commensal Escherichia coli using PCR or WGS

Identification of a Novel Trimethoprim Resistance Gene, dfrK, in a Methicillin-Resistant Staphylococcus aureus ST398 Strain and Its Physical Linkage to the Tetracycline Resistance Gene tet(L)

Factors That Cause Trimethoprim Resistance in Streptococcus pyogenes

Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use

Clinical and microbiological characteristics of patients colonized or infected by Stenotrophomonas maltophilia : is resistance to sulfamethoxazole/trimethoprim a problem?

Exploration into the origins and mobilization of di-hydrofolate reductase genes and the emergence of clinical resistance to trimethoprim

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