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RNA-guided DNA insertion with CRISPR-associated transposases

Science (American Association for the Advancement of Science), 2019-07, Vol.365 (6448), p.48-53

2019

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Recurrent evolution of vertebrate transcription factors by transposase capture

Science (American Association for the Advancement of Science), 2021-02, Vol.371 (6531)

2021

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Chromatin accessibility profiling by ATAC-seq

Nature protocols, 2022-06, Vol.17 (6), p.1518-1552

2022

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CUT&Tag for efficient epigenomic profiling of small samples and single cells

Nature communications, 2019-04, Vol.10 (1), p.1930-1930, Article 1930

2019

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Structures of the holo CRISPR RNA-guided transposon integration complex

Nature (London), 2023-01, Vol.613 (7945), p.775-782

2023

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Efficient low-cost chromatin profiling with CUT&Tag

Nature protocols, 2020-10, Vol.15 (10), p.3264-3283

2020

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A programmable seekRNA guides target selection by IS1111 and IS110 type insertion sequences

Nature communications, 2024-06, Vol.15 (1), p.5235-15, Article 5235

2024

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Dual modes of CRISPR-associated transposon homing

Cell, 2021-04, Vol.184 (9), p.2441-2453.e18

2021

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Structural basis for DNA targeting by the Tn7 transposon

Nature structural & molecular biology, 2022-02, Vol.29 (2), p.143-151

2022

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Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (32), p.e2202590119-e2202590119

2022

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The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5′-transposon end

Molecular cell, 2021-10, Vol.81 (20), p.4271-4286.e4

2021

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PGBD5 promotes site-specific oncogenic mutations in human tumors

Nature genetics, 2017-07, Vol.49 (7), p.1005-1014

2017

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ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells

Nature methods, 2022-10, Vol.19 (10), p.1243-1249

2022

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Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance

Cell, 2018-03, Vol.173 (1), p.208-220.e20

2018

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Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq)

Nature communications, 2019-08, Vol.10 (1), p.3747-3747, Article 3747

2019

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Solid-phase capture and profiling of open chromatin by spatial ATAC

Nature biotechnology, 2023-08, Vol.41 (8), p.1085-1088

2023

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RNA sequencing by direct tagmentation of RNA/DNA hybrids

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (6), p.2886-2893

2020

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Structures of a RAG-like transposase during cut-and-paste transposition

Nature (London), 2019-11, Vol.575 (7783), p.540-544

2019

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catalytic domain of all eukaryotic cut-and-paste transposase superfamilies

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (19), p.7884-7889

2011

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CRISPR/dCas9‐mediated transposition with specificity and efficiency of site‐directed genomic insertions

The FASEB journal, 2021-02, Vol.35 (2), p.e21359-n/a

2021

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Tn5 transposase and tagmentation procedures for massively scaled sequencing projects

Genome research, 2014-12, Vol.24 (12), p.2033-2040

2014

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Improving genetic transformation rates in honeybees

Scientific reports, 2018-11, Vol.8 (1), p.16534-6, Article 16534

2018

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High-content single-cell combinatorial indexing

Nature biotechnology, 2021-12, Vol.39 (12), p.1574-1580

2021

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Target site selection and remodelling by type V CRISPR-transposon systems

Nature (London), 2021-11, Vol.599 (7885), p.497-502

2021

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ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome

Genome research, 2022-08, Vol.32 (8), p.1529-1541

2022

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RNA-guided DNA insertion with CRISPR-associated transposases

Recurrent evolution of vertebrate transcription factors by transposase capture

Chromatin accessibility profiling by ATAC-seq

CUT&Tag for efficient epigenomic profiling of small samples and single cells

Structures of the holo CRISPR RNA-guided transposon integration complex

Efficient low-cost chromatin profiling with CUT&Tag

A programmable seekRNA guides target selection by IS1111 and IS110 type insertion sequences

Dual modes of CRISPR-associated transposon homing

Structural basis for DNA targeting by the Tn7 transposon

Mechanistic details of CRISPR-associated transposon recruitment and integration revealed by cryo-EM

The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5′-transposon end

PGBD5 promotes site-specific oncogenic mutations in human tumors

ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells

Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance

Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq)

Solid-phase capture and profiling of open chromatin by spatial ATAC

RNA sequencing by direct tagmentation of RNA/DNA hybrids

Structures of a RAG-like transposase during cut-and-paste transposition

catalytic domain of all eukaryotic cut-and-paste transposase superfamilies

CRISPR/dCas9‐mediated transposition with specificity and efficiency of site‐directed genomic insertions

Tn5 transposase and tagmentation procedures for massively scaled sequencing projects

Improving genetic transformation rates in honeybees

High-content single-cell combinatorial indexing

Target site selection and remodelling by type V CRISPR-transposon systems

ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome

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