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Modulation of miR-205/ EGLN2 by rosuvastatin mitigates colistin-induced nephrotoxicity in rats: Involvement of ATF4/ CHOP and Nrf2 pathways

Biomedicine & pharmacotherapy, 2023-01, Vol.157, p.114042, Article 114042

2023

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Pomegranate and green tea extracts protect against ER stress induced by a high-fat diet in skeletal muscle of mice

European journal of nutrition, 2015-04, Vol.54 (3), p.377-389

2015

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Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

The Journal of cell biology, 2017-07, Vol.216 (7), p.2027-2045

2017

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Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells

Trends in endocrinology and metabolism, 2017-11, Vol.28 (11), p.794-806

2017

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Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver

Molecular biology of the cell, 2016-05, Vol.27 (9), p.1536-1551

2016

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Nature cell biology, 2013-05, Vol.15 (5), p.481-490

2013

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The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

Current molecular medicine, 2016-07, Vol.16 (6), p.533-544

2016

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ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1–TFAM signalling in alcoholic steatohepatitis

Gut, 2021-10, Vol.70 (10), p.1933-1945

2021

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Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway

Nature (London), 2020-03, Vol.579 (7799), p.427-432

2020

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mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6274), p.728-733

2016

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Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types

The Journal of neuroscience, 2020-07, Vol.40 (27), p.5177-5195

2020

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A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

Nature communications, 2017-07, Vol.8 (1), p.133-15, Article 133

2017

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Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes

Molecular cell, 2020-08, Vol.79 (4), p.546-560.e7

2020

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Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules

Cell, 2020-12, Vol.183 (7), p.1801-1812.e13

2020

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The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress

The Journal of biological chemistry, 2019-05, Vol.294 (20), p.8197-8217

2019

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ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner

Oncogene, 2017-10, Vol.36 (40), p.5593-5608

2017

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Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer

The Journal of experimental medicine, 2020-09, Vol.217 (9)

2020

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ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation

Cancer cell, 2012-11, Vol.22 (5), p.631-644

2012

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miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner

Molecular cell, 2012-11, Vol.48 (3), p.353-364

2012

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Endoplasmic Reticulum (ER) Stress and Hypoxia Response Pathways Interact to Potentiate Hypoxia-inducible Factor 1 (HIF-1) Transcriptional Activity on Targets Like Vascular Endothelial Growth Factor (VEGF)

The Journal of biological chemistry, 2014-02, Vol.289 (6), p.3352-3364

2014

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Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

Gastroenterology (New York, N.Y. 1943), 2008-02, Vol.134 (2), p.568-576

2008

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Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions

Cell, 2014-08, Vol.158 (5), p.1159-1172

2014

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The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

eLife, 2021-03, Vol.10

2021

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HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

Cancer research (Chicago, Ill.), 2017-04, Vol.77 (8), p.2064-2077

2017

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Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

Nature communications, 2021-01, Vol.12 (1), p.366-366, Article 366

2021

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Modulation of miR-205/ EGLN2 by rosuvastatin mitigates colistin-induced nephrotoxicity in rats: Involvement of ATF4/ CHOP and Nrf2 pathways

Pomegranate and green tea extracts protect against ER stress induced by a high-fat diet in skeletal muscle of mice

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells

Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1–TFAM signalling in alcoholic steatohepatitis

Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes

Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules

The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress

ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner

Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer

ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation

miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner

Endoplasmic Reticulum (ER) Stress and Hypoxia Response Pathways Interact to Potentiate Hypoxia-inducible Factor 1 (HIF-1) Transcriptional Activity on Targets Like Vascular Endothelial Growth Factor (VEGF)

Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions

The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

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