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In Situ Tumor Vaccination with Calcium‐Linked Degradable Coacervate Nanocomplex Co‐Delivering Photosensitizer and TLR7/8 Agonist to Trigger Effective Anti‐Tumor Immune Responses

Advanced healthcare materials, 2022-06, Vol.11 (12), p.e2102781-n/a

2022

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Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

The Journal of immunology (1950), 2011-04, Vol.186 (8), p.4794-4804

2011

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Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists

The Journal of immunology (1950), 2017-08, Vol.199 (4), p.1405-1417

2017

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Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity

Immunological reviews, 2007-12, Vol.220 (1), p.251-269

2007

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In vivo cancer vaccination: Which dendritic cells to target and how?

Cancer treatment reviews, 2018-12, Vol.71, p.88-101

2018

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Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBV152: a double-blind, randomised, phase 1 trial

The Lancet infectious diseases, 2021-05, Vol.21 (5), p.637-646

2021

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Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice

International journal of infectious diseases, 2014-12, Vol.29 (C), p.31-36

2014

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Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells

PloS one, 2010-11, Vol.5 (11), p.e15041-e15041

2010

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T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

Nature communications, 2017-11, Vol.8 (1), p.1747-12, Article 1747

2017

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TLR8 Is a Sensor of RNase T2 Degradation Products

Cell, 2019-11, Vol.179 (6), p.1264-1275.e13

2019

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Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants

Advanced drug delivery reviews, 2021-08, Vol.175, p.113803-113803, Article 113803

2021

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TLRs to cytokines: Mechanistic insights from the imiquimod mouse model of psoriasis

European journal of immunology, 2013-12, Vol.43 (12), p.3138-3146

2013

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The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

Nature communications, 2019-10, Vol.10 (1), p.4682-15, Article 4682

2019

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Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes

Cell death & disease, 2018-05, Vol.9 (5), p.499-14, Article 499

2018

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Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization

The Journal of immunology (1950), 2016-12, Vol.197 (11), p.4413-4424

2016

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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Nature biomedical engineering, 2018-08, Vol.2 (8), p.578

2018

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Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles

Journal of the American Chemical Society, 2020-07, Vol.142 (28), p.12133-12139

2020

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A pH-/Enzyme-Responsive Nanoparticle Selectively Targets Endosomal Toll-like Receptors to Potentiate Robust Cancer Vaccination

Nano letters, 2022-04, Vol.22 (7), p.2978-2987

2022

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Increased expression of interleukin 36 in chronic rhinosinusitis and its contribution to chemokine secretion and increased epithelial permeability

Cytokine (Philadelphia, Pa.), 2020-01, Vol.125, p.154798-154798, Article 154798

2020

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pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (29), p.8098-8103

2016

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TLR7 and TLR8 gene variations and susceptibility to hepatitis C virus infection

PloS one, 2011-10, Vol.6 (10), p.e26235-e26235

2011

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Persistent Toll-like receptor 7 stimulation induces behavioral and molecular innate immune tolerance

Brain, behavior, and immunity, 2019-11, Vol.82, p.338-353

2019

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Attenuated innate immune defenses in very premature neonates during the neonatal period

Pediatric research, 2015-11, Vol.78 (5), p.492-497

2015

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Determinants of Activity at Human Toll-like Receptors 7 and 8: Quantitative Structure–Activity Relationship (QSAR) of Diverse Heterocyclic Scaffolds

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.7955-7970

2014

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In Situ Tumor Vaccination with Calcium‐Linked Degradable Coacervate Nanocomplex Co‐Delivering Photosensitizer and TLR7/8 Agonist to Trigger Effective Anti‐Tumor Immune Responses

Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines

Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor Agonists

Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity

In vivo cancer vaccination: Which dendritic cells to target and how?

Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBV152: a double-blind, randomised, phase 1 trial

Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice

Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

TLR8 Is a Sensor of RNase T2 Degradation Products

Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants

TLRs to cytokines: Mechanistic insights from the imiquimod mouse model of psoriasis

The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes

Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization

Human TLR-7-, -8-, and -9-Mediated Induction of IFN-α/β and -λ Is IRAK-4 Dependent and Redundant for Protective Immunity to Viruses

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles

A pH-/Enzyme-Responsive Nanoparticle Selectively Targets Endosomal Toll-like Receptors to Potentiate Robust Cancer Vaccination

Increased expression of interleukin 36 in chronic rhinosinusitis and its contribution to chemokine secretion and increased epithelial permeability

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

TLR7 and TLR8 gene variations and susceptibility to hepatitis C virus infection

Persistent Toll-like receptor 7 stimulation induces behavioral and molecular innate immune tolerance

Attenuated innate immune defenses in very premature neonates during the neonatal period

Determinants of Activity at Human Toll-like Receptors 7 and 8: Quantitative Structure–Activity Relationship (QSAR) of Diverse Heterocyclic Scaffolds

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