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Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery

BioMed research international, 2021, Vol.2021, p.9968602-14

2021

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Targeting Topoisomerase I in the Era of Precision Medicine

Clinical cancer research, 2019-11, Vol.25 (22), p.6581-6589

2019

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Bevacizumab Combined With Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer: The AURELIA Open-Label Randomized Phase III Trial

Journal of clinical oncology, 2014-05, Vol.32 (13), p.1302-1308

2014

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Image-guided thermosensitive liposomes for focused ultrasound drug delivery: Using NIRF-labelled lipids and topotecan to visualise the effects of hyperthermia in tumours

Journal of controlled release, 2018-06, Vol.280, p.87-98

2018

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Development of topotecan loaded lipid nanoparticles for chemical stabilization and prolonged release

European journal of pharmaceutics and biopharmaceutics, 2011-09, Vol.79 (1), p.189-196

2011

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ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

Nature communications, 2019-01, Vol.10 (1), p.87-18, Article 87

2019

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Carboplatin plus etoposide versus topotecan as second-line treatment for patients with sensitive relapsed small-cell lung cancer: an open-label, multicentre, randomised, phase 3 trial

The lancet oncology, 2020-09, Vol.21 (9), p.1224-1233

2020

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A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid Tumors

Clinical cancer research, 2018-02, Vol.24 (4), p.744-752

2018

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Safety and tolerability of the poly(ADP-ribose) polymerase (PARP) inhibitor, olaparib (AZD2281) in combination with topotecan for the treatment of patients with advanced solid tumors: a phase I study

Investigational new drugs, 2012-08, Vol.30 (4), p.1493-1500

2012

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Development of a highly stable and targetable nanoliposomal formulation of topotecan

Journal of controlled release, 2010-01, Vol.141 (1), p.13-21

2010

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Intravitreal Topotecan for Vitreous Seeds in Retinoblastoma

Ophthalmology (Rochester, Minn.), 2024-10, Vol.131 (10), p.1215-1224

2024

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Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

Nature (London), 2011-12, Vol.481 (7380), p.185-189

2011

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Dual modulation of blue-fluorescent carbon dots for simultaneous detection of topotecan and pantoprazole

Analytical methods, 2024-05, Vol.16 (2), p.3287-3296

2024

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Multipronged, strategic delivery of paclitaxel-topotecan using engineered liposomes to ovarian cancer

Drug development and industrial pharmacy, 2016-01, Vol.42 (1), p.136-149

2016

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Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic Oncology Group 240)

The Lancet (British edition), 2017-10, Vol.390 (10103), p.1654-1663

2017

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PK/TD modeling for prediction of the effects of 8C2, an anti-topotecan mAb, on topotecan-induced toxicity in mice

International journal of pharmaceutics, 2014-04, Vol.465 (1-2), p.228-238

2014

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Multifunctional enveloped mesoporous silica nanoparticles for subcellular co-delivery of drug and therapeutic peptide

Scientific reports, 2014-08, Vol.4, p.6064

2014

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Efficacy and Safety of Rovalpituzumab Tesirine Compared With Topotecan as Second-Line Therapy in DLL3-High SCLC: Results From the Phase 3 TAHOE Study

Journal of thoracic oncology, 2021-09, Vol.16 (9), p.1547-1558

2021

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Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models

European journal of medicinal chemistry, 2019-01, Vol.161, p.581-593

2019

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A Phase I Study of Topotecan, Carboplatin and the PARP Inhibitor Veliparib in Acute Leukemias, Aggressive Myeloproliferative Neoplasms, and Chronic Myelomonocytic Leukemia

Clinical cancer research, 2017-02, Vol.23 (4), p.899-907

2017

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Patient-Reported Outcome Results From the Open-Label Phase III AURELIA Trial Evaluating Bevacizumab-Containing Therapy for Platinum-Resistant Ovarian Cancer

Journal of clinical oncology, 2014-05, Vol.32 (13), p.1309-1316

2014

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Accelerated Blood Clearance of Pegylated Liposomal Topotecan: Influence of Polyethylene Glycol Grafting Density and Animal Species

Journal of pharmaceutical sciences, 2012-10, Vol.101 (10), p.3864-3876

2012

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Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors

Journal of clinical oncology, 2018-06, Vol.36 (16), p.1594-1602

2018

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Dual-Targeting Topotecan Liposomes Modified with Tamoxifen and Wheat Germ Agglutinin Significantly Improve Drug Transport across the Blood−Brain Barrier and Survival of Brain Tumor-Bearing Animals

Molecular pharmaceutics, 2009-06, Vol.6 (3), p.905-917

2009

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Improved Survival with Bevacizumab in Advanced Cervical Cancer

The New England journal of medicine, 2014-02, Vol.370 (8), p.734-743

2014

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Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery

Targeting Topoisomerase I in the Era of Precision Medicine

Bevacizumab Combined With Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer: The AURELIA Open-Label Randomized Phase III Trial

Image-guided thermosensitive liposomes for focused ultrasound drug delivery: Using NIRF-labelled lipids and topotecan to visualise the effects of hyperthermia in tumours

Development of topotecan loaded lipid nanoparticles for chemical stabilization and prolonged release

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

Carboplatin plus etoposide versus topotecan as second-line treatment for patients with sensitive relapsed small-cell lung cancer: an open-label, multicentre, randomised, phase 3 trial

A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid Tumors

Safety and tolerability of the poly(ADP-ribose) polymerase (PARP) inhibitor, olaparib (AZD2281) in combination with topotecan for the treatment of patients with advanced solid tumors: a phase I study

Development of a highly stable and targetable nanoliposomal formulation of topotecan

Intravitreal Topotecan for Vitreous Seeds in Retinoblastoma

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

Dual modulation of blue-fluorescent carbon dots for simultaneous detection of topotecan and pantoprazole

Multipronged, strategic delivery of paclitaxel-topotecan using engineered liposomes to ovarian cancer

Bevacizumab for advanced cervical cancer: final overall survival and adverse event analysis of a randomised, controlled, open-label, phase 3 trial (Gynecologic Oncology Group 240)

PK/TD modeling for prediction of the effects of 8C2, an anti-topotecan mAb, on topotecan-induced toxicity in mice

Multifunctional enveloped mesoporous silica nanoparticles for subcellular co-delivery of drug and therapeutic peptide

Efficacy and Safety of Rovalpituzumab Tesirine Compared With Topotecan as Second-Line Therapy in DLL3-High SCLC: Results From the Phase 3 TAHOE Study

Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models

A Phase I Study of Topotecan, Carboplatin and the PARP Inhibitor Veliparib in Acute Leukemias, Aggressive Myeloproliferative Neoplasms, and Chronic Myelomonocytic Leukemia

Patient-Reported Outcome Results From the Open-Label Phase III AURELIA Trial Evaluating Bevacizumab-Containing Therapy for Platinum-Resistant Ovarian Cancer

Accelerated Blood Clearance of Pegylated Liposomal Topotecan: Influence of Polyethylene Glycol Grafting Density and Animal Species

Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors

Dual-Targeting Topotecan Liposomes Modified with Tamoxifen and Wheat Germ Agglutinin Significantly Improve Drug Transport across the Blood−Brain Barrier and Survival of Brain Tumor-Bearing Animals

Improved Survival with Bevacizumab in Advanced Cervical Cancer

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