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The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure

The Journal of biological chemistry, 2012-10, Vol.287 (42), p.34979-34991

2012

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Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

Cancer cell, 2014-08, Vol.26 (2), p.177-189

2014

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Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity

Cancer research (Chicago, Ill.), 2010-02, Vol.70 (3), p.1101-1110

2010

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Multimerization of an Apoptogenic TRAIL-Mimicking Peptide by Using Adamantane-Based Dendrons

Chemistry : a European journal, 2013-01, Vol.19 (5), p.1762-1768

2013

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The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex

Acta crystallographica. Section F, Structural biology communications, 2015-10, Vol.71 (10), p.1273-1281

2015

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DR4-selective Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Variants Obtained by Structure-based Design

The Journal of biological chemistry, 2008-07, Vol.283 (29), p.20560-20568

2008

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An HPLC method associated with a thermodynamic analysis to compare the binding of TRAIL and its nanovectorized form to death receptors DR4 and DR5 and their relationship to cytotoxicity

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-11, Vol.1036-1037, p.142-148

2016

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Comparative binding to DR4 and DR5 receptors of TRAIL and BNNTs/PAHE/mPEG‐DSPE/TRAIL nanoparticles

Journal of molecular recognition, 2017-07, Vol.30 (7), p.n/a

2017

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TRAIL/TRAIL-R in hematologic malignancies

Journal of cellular biochemistry, 2010-05, Vol.110 (1), p.21-34

Testa, Ugo

2010

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Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation

International journal of molecular sciences, 2018-03, Vol.19 (3), p.715

Micheau, Olivier

2018

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Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling

Cell, 2019-03, Vol.176 (6), p.1477-1489.e14

2019

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Enhancement of Antitumor Properties of rhTRAIL by Affinity Increase toward Its Death Receptors

Biochemistry (Easton), 2009-03, Vol.48 (10), p.2180-2191

2009

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Anticancer Platelet-Mimicking Nanovehicles

Advanced materials (Weinheim), 2015-11, Vol.27 (44), p.7043-7050

2015

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Multiple hyperthermia-mediated release of TRAIL/SPION nanocomplex from thermosensitive polymeric hydrogels for combination cancer therapy

Biomaterials, 2017-07, Vol.132, p.16-27

2017

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Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy

ACS nano, 2018-02, Vol.12 (2), p.912-931

2018

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O‐glycans on death receptors in cells modulate their sensitivity to TRAIL‐induced apoptosis through affecting on their stability and oligomerization

The FASEB journal, 2020-09, Vol.34 (9), p.11786-11801

2020

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Inhalable self-assembled albumin nanoparticles for treating drug-resistant lung cancer

Journal of controlled release, 2015-01, Vol.197, p.199-207

2015

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Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene

Advanced materials (Weinheim), 2015-02, Vol.27 (6), p.1021-1028

2015

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Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients

BMC cancer, 2020-09, Vol.20 (1), p.873-873, Article 873

2020

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Engineering Exosomes Endowed with Targeted Delivery of Triptolide for Malignant Melanoma Therapy

ACS applied materials & interfaces, 2021-09, Vol.13 (36), p.42411-42428

2021

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Nanovectorization of TRAIL with Single Wall Carbon Nanotubes Enhances Tumor Cell Killing

Nano letters, 2015-02, Vol.15 (2), p.891-895

2015

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Facile one-pot formulation of TRAIL-embedded paclitaxel-bound albumin nanoparticles for the treatment of pancreatic cancer

International journal of pharmaceutics, 2015-10, Vol.494 (1), p.506-515

2015

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Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity

Oncogene, 2016-03, Vol.35 (10), p.1261-1270

2016

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Regulation of the human TRAIL gene

Cancer biology & therapy, 2012-10, Vol.13 (12), p.1143-1151

2012

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The conformation of the extracellular binding domain of Death Receptor 5 in the presence and absence of the activating ligand TRAIL: A molecular dynamics study

Proteins, structure, function, and bioinformatics, 2008-02, Vol.70 (2), p.333-343

2008

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The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure

Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity

Multimerization of an Apoptogenic TRAIL-Mimicking Peptide by Using Adamantane-Based Dendrons

The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex

DR4-selective Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Variants Obtained by Structure-based Design

An HPLC method associated with a thermodynamic analysis to compare the binding of TRAIL and its nanovectorized form to death receptors DR4 and DR5 and their relationship to cytotoxicity

Comparative binding to DR4 and DR5 receptors of TRAIL and BNNTs/PAHE/mPEG‐DSPE/TRAIL nanoparticles

TRAIL/TRAIL-R in hematologic malignancies

Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation

Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling

Enhancement of Antitumor Properties of rhTRAIL by Affinity Increase toward Its Death Receptors

Anticancer Platelet-Mimicking Nanovehicles

Multiple hyperthermia-mediated release of TRAIL/SPION nanocomplex from thermosensitive polymeric hydrogels for combination cancer therapy

Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy

O‐glycans on death receptors in cells modulate their sensitivity to TRAIL‐induced apoptosis through affecting on their stability and oligomerization

Inhalable self-assembled albumin nanoparticles for treating drug-resistant lung cancer

Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene

Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients

Engineering Exosomes Endowed with Targeted Delivery of Triptolide for Malignant Melanoma Therapy

Nanovectorization of TRAIL with Single Wall Carbon Nanotubes Enhances Tumor Cell Killing

Facile one-pot formulation of TRAIL-embedded paclitaxel-bound albumin nanoparticles for the treatment of pancreatic cancer

Decoy receptors block TRAIL sensitivity at a supracellular level: the role of stromal cells in controlling tumour TRAIL sensitivity

Regulation of the human TRAIL gene

The conformation of the extracellular binding domain of Death Receptor 5 in the presence and absence of the activating ligand TRAIL: A molecular dynamics study

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