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Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): Clinical and Neuropathological Associations

Journal of neuropathology and experimental neurology, 2020-03, Vol.79 (3), p.305-313

2020

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TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration

Molecular and cellular neuroscience, 2019-10, Vol.100, p.103396-103396, Article 103396

2019

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Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease

Acta neuropathologica, 2022-01, Vol.143 (1), p.15-31

2022

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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Nature (London), 2020-12, Vol.588 (7838), p.459-465

2020

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Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19614-19624

2013

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RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy

Brain (London, England : 1878), 2019-12, Vol.142 (12), p.3753-3770

2019

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Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease

Brain (London, England : 1878), 2017-12, Vol.140 (12), p.3081-3104

2017

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Exosome secretion is a key pathway for clearance of pathological TDP-43

Brain (London, England : 1878), 2016-12, Vol.139 (Pt 12), p.3187-3201

2016

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TDP-43 protein interactome informs about perturbed canonical pathways and may help develop personalized medicine approaches for patients with TDP-43 pathology

Drug discovery today, 2023-11, Vol.28 (11), p.103769-103769, Article 103769

2023

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TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

Journal of neuropathology and experimental neurology, 2010-09, Vol.69 (9), p.918-929

2010

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Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms

Brain (London, England : 1878), 2020-01, Vol.143 (1), p.303-319

2020

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Physiological functions and pathobiology of TDP‐43 and FUS/TLS proteins

Journal of neurochemistry, 2016-08, Vol.138 (S1), p.95-111

2016

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Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy

RNA biology, 2021-11, Vol.18 (11), p.1546-1554

2021

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Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4705

2021

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Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A

Acta neuropathologica, 2015-01, Vol.129 (1), p.53-64

2015

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Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease

Journal of neuropathology and experimental neurology, 2022-12, Vol.81 (12), p.975-987

2022

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Metabolism and mis-metabolism of the neuropathological signature protein TDP-43

Journal of cell science, 2014-07, Vol.127 (Pt 14), p.3024-3038

2014

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Prevalence of transactive response DNA‐binding protein 43 (TDP‐43) proteinopathy in cognitively normal older adults: systematic review and meta‐analysis

Neuropathology and applied neurobiology, 2018-04, Vol.44 (3), p.286-297

2018

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Distribution and characteristics of transactive response DNA binding protein 43 kDa pathology in progressive supranuclear palsy

Movement disorders, 2017-02, Vol.32 (2), p.246-255

2017

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Cortical influences drive amyotrophic lateral sclerosis

Journal of neurology, neurosurgery and psychiatry, 2017-11, Vol.88 (11), p.917-924

2017

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Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD

Neurotherapeutics, 2022-07, Vol.19 (4), p.1061-1084

2022

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Hippocampal neurobiology and function in an aged mouse model of TDP-43 proteinopathy in an APP/PSEN1 background

Neuroscience letters, 2021-07, Vol.758, p.136010-136010, Article 136010

2021

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RNA-binding proteins with prion-like domains in health and disease

Biochemical journal, 2017-04, Vol.474 (8), p.1417-1438

2017

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Somatic TARDBP variants as a cause of semantic dementia

Brain (London, England : 1878), 2020-12, Vol.143 (12), p.3827-3841

2020

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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

Neurotherapeutics, 2015-04, Vol.12 (2), p.352-363

2015

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Limbic Predominant Age-Related TDP-43 Encephalopathy (LATE): Clinical and Neuropathological Associations

TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration

Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency

Structural Transformation of the Amyloidogenic Core Region of TDP-43 Protein Initiates Its Aggregation and Cytoplasmic Inclusion

RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy

Progranulin: a new avenue towards the understanding and treatment of neurodegenerative disease

Exosome secretion is a key pathway for clearance of pathological TDP-43

TDP-43 protein interactome informs about perturbed canonical pathways and may help develop personalized medicine approaches for patients with TDP-43 pathology

TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms

Physiological functions and pathobiology of TDP‐43 and FUS/TLS proteins

Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy

Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD

Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A

Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease

Metabolism and mis-metabolism of the neuropathological signature protein TDP-43

Prevalence of transactive response DNA‐binding protein 43 (TDP‐43) proteinopathy in cognitively normal older adults: systematic review and meta‐analysis

Distribution and characteristics of transactive response DNA binding protein 43 kDa pathology in progressive supranuclear palsy

Cortical influences drive amyotrophic lateral sclerosis

Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD

Hippocampal neurobiology and function in an aged mouse model of TDP-43 proteinopathy in an APP/PSEN1 background

RNA-binding proteins with prion-like domains in health and disease

Somatic TARDBP variants as a cause of semantic dementia

TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets

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