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The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 Regulatory Feedback Circuit Affects the Proliferation, Migration, and Invasion of Colon Cancer SW480 Cells

Cellular physiology and biochemistry, 2018-10, Vol.49 (4), p.1539-1550

2018

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Conformational Dynamics and Cooperativity Drive the Specificity of a Protein-Ligand Interaction

Biophysical journal, 2019-06, Vol.116 (12), p.2314-2330

2019

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Whole Genome Sequencing Prioritizes CHEK2, EWSR1 , and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer

Frontiers in endocrinology (Lausanne), 2021-02, Vol.12, p.600682-600682

2021

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TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain

The Journal of clinical investigation, 2022-12, Vol.132 (24), p.1-15

2022

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The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions

The Journal of neuroscience, 2021-02, Vol.41 (6), p.1191-1206

2021

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TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancer

Cell death & disease, 2019-03, Vol.10 (4), p.267-267, Article 267

2019

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Decreased Tiam1‐mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia

Journal of cellular and molecular medicine, 2024-06, Vol.28 (11), p.e18443-n/a

2024

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MicroRNA-183 as a Novel Regulator Protects Against Cardiomyocytes Hypertrophy via Targeting TIAM1

American journal of hypertension, 2022-01, Vol.35 (1), p.87-95

2022

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Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101172-101172, Article 101172

2021

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Histone methyltransferase SETDB1 promotes cells proliferation and migration by interacting withTiam1 in hepatocellular carcinoma

BMC cancer, 2018-05, Vol.18 (1), p.539-539, Article 539

2018

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TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

Cell reports (Cambridge), 2021-11, Vol.37 (6), p.109979-109979, Article 109979

2021

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TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization

eLife, 2019-01, Vol.8

2019

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RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma

International journal of biological sciences, 2022-01, Vol.18 (10), p.4245-4259

2022

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A hormone receptor pathway cell-autonomously delays neuron morphological aging by suppressing endocytosis

PLoS biology, 2019-10, Vol.17 (10), p.e3000452-e3000452

2019

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Single-Protein Tracking to Study Protein Interactions During Integrin-Based Migration

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2217, p.85

2021

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The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction-dependent manner

PloS one, 2017-11, Vol.12 (11), p.e0187094-e0187094

2017

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Upregulation of Tiam1 contributes to cervical cancer disease progression and indicates poor survival outcome

Human pathology, 2018-05, Vol.75, p.179-188

2018

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Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma

Cell research, 2016-10, Vol.26 (10), p.1149-1164

2016

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Increased Rac1 Activation in the Enhanced Carbachol-Induced Bronchial Smooth Muscle Contraction of Repeatedly Antigen-Challenged Mice

Biological and Pharmaceutical Bulletin, 2019/09/01, Vol.42(9), pp.1605-1607

2019

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The inhibition of the effect and mechanism of vascular intimal hyperplasia in Tiam1 knockout mice

Biochemical and biophysical research communications, 2018-02, Vol.497 (1), p.248-255

2018

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Computational Design of the Tiam1 PDZ Domain and Its Ligand Binding

Journal of chemical theory and computation, 2017-05, Vol.13 (5), p.2271-2289

2017

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Macrophage migration inhibitory factor siRNA inhibits hepatic metastases of colorectal cancer cells

Frontiers in bioscience, 2017-03, Vol.22 (8), p.1365-1378, Article 4549

2017

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5‐Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor‐induced cell migration through Tiam1 upregulation and Rac1 activation

Cancer science, 2014-03, Vol.105 (3), p.290-296

2014

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Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

Nature reviews. Cancer, 2010-12, Vol.10 (12), p.842-857

2010

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Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

Nature (London), 2012-03, Vol.483 (7391), p.589-593

2012

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The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 Regulatory Feedback Circuit Affects the Proliferation, Migration, and Invasion of Colon Cancer SW480 Cells

Conformational Dynamics and Cooperativity Drive the Specificity of a Protein-Ligand Interaction

Whole Genome Sequencing Prioritizes CHEK2, EWSR1 , and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer

TIAM1-mediated synaptic plasticity underlies comorbid depression-like and ketamine antidepressant-like actions in chronic pain

The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions

TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancer

Decreased Tiam1‐mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia

MicroRNA-183 as a Novel Regulator Protects Against Cardiomyocytes Hypertrophy via Targeting TIAM1

Identification of Rac guanine nucleotide exchange factors promoting Lgl1 phosphorylation in glioblastoma

Histone methyltransferase SETDB1 promotes cells proliferation and migration by interacting withTiam1 in hepatocellular carcinoma

TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization

RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma

A hormone receptor pathway cell-autonomously delays neuron morphological aging by suppressing endocytosis

Single-Protein Tracking to Study Protein Interactions During Integrin-Based Migration

The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction-dependent manner

Upregulation of Tiam1 contributes to cervical cancer disease progression and indicates poor survival outcome

Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma

Increased Rac1 Activation in the Enhanced Carbachol-Induced Bronchial Smooth Muscle Contraction of Repeatedly Antigen-Challenged Mice

The inhibition of the effect and mechanism of vascular intimal hyperplasia in Tiam1 knockout mice

Computational Design of the Tiam1 PDZ Domain and Its Ligand Binding

Macrophage migration inhibitory factor siRNA inhibits hepatic metastases of colorectal cancer cells

5‐Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor‐induced cell migration through Tiam1 upregulation and Rac1 activation

Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

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