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Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin

Nature structural & molecular biology, 2021-03, Vol.28 (3), p.319-325

2021

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Structure of the Ebola virus polymerase complex

Nature (London), 2022-10, Vol.610 (7931), p.394-401

2022

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Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases

Journal of molecular biology, 2012-06, Vol.419 (3-4), p.198-210

2012

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Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages

International immunopharmacology, 2023-07, Vol.120, p.110295-110295, Article 110295

2023

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Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue

Bioorganic & medicinal chemistry, 2023-09, Vol.92, p.117424-117424, Article 117424

2023

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Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds

PloS one, 2014-03, Vol.9 (3), p.e91765

2014

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100 Years of Suramin

Antimicrobial agents and chemotherapy, 2020-02, Vol.64 (3)

2020

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Repurposing suramin for the treatment of breast cancer lung metastasis with glycol chitosan-based nanoparticles

Acta biomaterialia, 2019-01, Vol.84, p.378-390

2019

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Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays

Scientific reports, 2020-11, Vol.10 (1), p.18850, Article 18850

2020

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First comprehensive untargeted metabolomics study of suramin-treated Trypanosoma brucei: an integrated data analysis workflow from multifactor data modelling to functional analysis

Metabolomics, 2024-02, Vol.20 (2), p.25-25, Article 25

2024

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Spatial modeling of prostate cancer metabolic gene expression reveals extensive heterogeneity and selective vulnerabilities

Scientific reports, 2020-02, Vol.10 (1), p.3490-3490, Article 3490

2020

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Suramin Targets the Conserved Ligand-Binding Pocket of Human Raf1 Kinase Inhibitory Protein

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.1151

2021

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Suramin interacts with the positively charged region surrounding the 5-fold axis of the EV-A71 capsid and inhibits multiple enterovirus A

Scientific reports, 2017-02, Vol.7 (1), p.42902-42902, Article 42902

2017

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Bis(benzofuran–thiazolidinone)s and bis(benzofuran–thiazinanone)s as inhibiting agents for chikungunya virus

Antiviral research, 2017-10, Vol.146, p.96-101

2017

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Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries

The American journal of sports medicine, 2021-09, Vol.49 (11), p.3102-3112

2021

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Phytochemical Screening, GC-MS Analysis, and Evaluating In Vivo Antitrypanosomal Effects of a Methanolic Extract of IGarcinia kola/I Nuts on Rats

Antibiotics (Basel), 2023-04, Vol.12 (4)

2023

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Using Covalent Labeling and Mass Spectrometry To Study Protein Binding Sites of Amyloid Inhibiting Molecules

Analytical chemistry (Washington), 2017-11, Vol.89 (21), p.11583-11591

2017

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Structure-Activity Studies on Suramin Analogues as Inhibitors of NAD+-Dependent Histone Deacetylases (Sirtuins)

ChemMedChem, 2007-10, Vol.2 (10), p.1419-1431

2007

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Polysulfonate suramin inhibits Zika virus infection

Antiviral research, 2017-07, Vol.143, p.186-194

2017

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Suramin Disturbs the Association of the N-Terminal Domain of SARS-CoV-2 Nucleocapsid Protein with RNA

Molecules (Basel, Switzerland), 2023-03, Vol.28 (6), p.2534

2023

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From Proteome to Potential Drugs: Integration of Subtractive Proteomics and Ensemble Docking for Drug Repurposing against Pseudomonas aeruginosa RND Superfamily Proteins

International journal of molecular sciences, 2024-08, Vol.25 (15), p.8027

2024

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Suramin Inhibits Chikungunya Virus Entry and Transmission

PloS one, 2015-07, Vol.10 (7), p.e0133511-e0133511

2015

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A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation

Journal of medicinal chemistry, 2016-02, Vol.59 (3), p.1021-1031

2016

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Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei

Molecular microbiology, 2018-01, Vol.107 (1), p.57-67

2018

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The anti-parasitic drug suramin potently inhibits formation of seminal amyloid fibrils and their interaction with HIV-1

The Journal of biological chemistry, 2019-09, Vol.294 (37), p.13740-13754

2019

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Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin

Structure of the Ebola virus polymerase complex

Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases

Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages

Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue

Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds

100 Years of Suramin

Repurposing suramin for the treatment of breast cancer lung metastasis with glycol chitosan-based nanoparticles

Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays

First comprehensive untargeted metabolomics study of suramin-treated Trypanosoma brucei: an integrated data analysis workflow from multifactor data modelling to functional analysis

Spatial modeling of prostate cancer metabolic gene expression reveals extensive heterogeneity and selective vulnerabilities

Suramin Targets the Conserved Ligand-Binding Pocket of Human Raf1 Kinase Inhibitory Protein

Suramin interacts with the positively charged region surrounding the 5-fold axis of the EV-A71 capsid and inhibits multiple enterovirus A

Bis(benzofuran–thiazolidinone)s and bis(benzofuran–thiazinanone)s as inhibiting agents for chikungunya virus

Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries

Phytochemical Screening, GC-MS Analysis, and Evaluating In Vivo Antitrypanosomal Effects of a Methanolic Extract of IGarcinia kola/I Nuts on Rats

Using Covalent Labeling and Mass Spectrometry To Study Protein Binding Sites of Amyloid Inhibiting Molecules

Structure-Activity Studies on Suramin Analogues as Inhibitors of NAD+-Dependent Histone Deacetylases (Sirtuins)

Polysulfonate suramin inhibits Zika virus infection

Suramin Disturbs the Association of the N-Terminal Domain of SARS-CoV-2 Nucleocapsid Protein with RNA

From Proteome to Potential Drugs: Integration of Subtractive Proteomics and Ensemble Docking for Drug Repurposing against Pseudomonas aeruginosa RND Superfamily Proteins

Suramin Inhibits Chikungunya Virus Entry and Transmission

A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation

Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei

The anti-parasitic drug suramin potently inhibits formation of seminal amyloid fibrils and their interaction with HIV-1

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