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Role of Substance P Neuropeptide in Inflammation, Wound Healing, and Tissue Homeostasis

The Journal of immunology (1950), 2017-09, Vol.199 (5), p.1543-1552

Suvas, Susmit

2017

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Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease

World journal of gastroenterology : WJG, 2017-07, Vol.23 (28), p.5068-5085

2017

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Neuropeptides activate human mast cell degranulation and chemokine production

Immunology, 2008-03, Vol.123 (3), p.398-410

2008

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Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P–induced human mast cell activation and degranulation in the hair follicle

Journal of allergy and clinical immunology, 2018-10, Vol.142 (4), p.1331-1333.e8

2018

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Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo

PloS one, 2020-01, Vol.15 (1), p.e0227817-e0227817

2020

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Migraine, Neurogenic Inflammation, Drug Development - Pharmacochemical Aspects

Current medicinal chemistry, 2017-01, Vol.24 (33), p.3649

2017

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The mucosal surfaces of both eyes are immunologically linked by a neurogenic inflammatory reflex involving TRPV1 and substance P

Mucosal immunology, 2018-09, Vol.11 (5), p.1441-1453

2018

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The role of substance P in inflammatory disease

Journal of cellular physiology, 2004-11, Vol.201 (2), p.167-180

2004

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Substance P represents a novel first-line defense mechanism in the nose

Journal of allergy and clinical immunology, 2018-01, Vol.141 (1), p.128-136.e3

2018

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Substance P ameliorates collagen II-induced arthritis in mice via suppression of the inflammatory response

Biochemical and biophysical research communications, 2014-10, Vol.453 (1), p.179-184

2014

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Influence of IL‐6, IL‐33, and TNF‐α on human mast cell activation: Lessons from single cell analysis by flow cytometry

Cytometry. Part B, Clinical cytometry, 2018-05, Vol.94 (3), p.405-411

2018

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Substance P activates human eosinophils

Experimental dermatology, 2015-07, Vol.24 (7), p.557-559

2015

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Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice

PloS one, 2013-05, Vol.8 (5), p.e62827

2013

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In vitro preconditioning of equine adipose mesenchymal stem cells with prostaglandin E 2 , substance P and their combination changes the cellular protein secretomics and improves their immunomodulatory competence without compromising stemness

Veterinary immunology and immunopathology, 2020-10, Vol.228, p.110100

2020

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The nervous system and innate immunity: the neuropeptide connection

Nature immunology, 2005-06, Vol.6 (6), p.558-564

2005

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Further Exploring the Brain–Skin Connection: Stress Worsens Dermatitis via Substance P-dependent Neurogenic Inflammation in Mice

Journal of investigative dermatology, 2008-02, Vol.128 (2), p.434-446

2008

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Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells

Journal of allergy and clinical immunology, 2015-12, Vol.136 (6), p.1690-1694

2015

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Interleukin 33 and interleukin 4 regulate interleukin 31 gene expression and secretion from human laboratory of allergic diseases 2 mast cells stimulated by substance P and/or immunoglobulin E

Allergy and asthma proceedings, 2018-03, Vol.39 (2), p.153-160

2018

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Expression of the NK-1 receptor on islet cells and invading immune cells in the non-obese diabetic mouse

Journal of autoimmunity, 2005-06, Vol.24 (4), p.269-279

2005

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Substance P as an Immunomodulatory Neuropeptide in a Mouse Model for Autoimmune Hair Loss (Alopecia Areata)

Journal of investigative dermatology, 2007-06, Vol.127 (6), p.1489-1497

2007

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Pathophysiology of itch and new treatments

Current opinion in allergy and clinical immunology, 2011-10, Vol.11 (5), p.420-427

2011

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Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA

Clinical and experimental allergy, 2006-09, Vol.36 (9), p.1192-1200

2006

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Substance P and eosinophils: an itchy connection

Experimental dermatology, 2015-12, Vol.24 (12), p.918-919

2015

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Nerve-related characteristics of ventral paratendinous tissue in chronic Achilles tendinosis

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2007-10, Vol.15 (10), p.1272-1279

2007

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Neurobiology of substance P and the NK1 receptor

The journal of clinical psychiatry, 2002, Vol.63 Suppl 11, p.6

Mantyh, Patrick W

2002

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Role of Substance P Neuropeptide in Inflammation, Wound Healing, and Tissue Homeostasis

Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease

Neuropeptides activate human mast cell degranulation and chemokine production

Nuclear factor (erythroid-derived 2)-like-2 pathway modulates substance P–induced human mast cell activation and degranulation in the hair follicle

Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo

Migraine, Neurogenic Inflammation, Drug Development - Pharmacochemical Aspects

The mucosal surfaces of both eyes are immunologically linked by a neurogenic inflammatory reflex involving TRPV1 and substance P

The role of substance P in inflammatory disease

Substance P represents a novel first-line defense mechanism in the nose

Substance P ameliorates collagen II-induced arthritis in mice via suppression of the inflammatory response

Influence of IL‐6, IL‐33, and TNF‐α on human mast cell activation: Lessons from single cell analysis by flow cytometry

Substance P activates human eosinophils

Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice

In vitro preconditioning of equine adipose mesenchymal stem cells with prostaglandin E 2 , substance P and their combination changes the cellular protein secretomics and improves their immunomodulatory competence without compromising stemness

The nervous system and innate immunity: the neuropeptide connection

Further Exploring the Brain–Skin Connection: Stress Worsens Dermatitis via Substance P-dependent Neurogenic Inflammation in Mice

Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells

Interleukin 33 and interleukin 4 regulate interleukin 31 gene expression and secretion from human laboratory of allergic diseases 2 mast cells stimulated by substance P and/or immunoglobulin E

Expression of the NK-1 receptor on islet cells and invading immune cells in the non-obese diabetic mouse

Substance P as an Immunomodulatory Neuropeptide in a Mouse Model for Autoimmune Hair Loss (Alopecia Areata)

Pathophysiology of itch and new treatments

Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA

Substance P and eosinophils: an itchy connection

Nerve-related characteristics of ventral paratendinous tissue in chronic Achilles tendinosis

Neurobiology of substance P and the NK1 receptor

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