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Safety profile of mineralocorticoid receptor antagonists: Spironolactone and eplerenone

International journal of cardiology, 2015-12, Vol.200, p.25-29

2015

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Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

The New England journal of medicine, 2011-01, Vol.364 (1), p.11-21

2011

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Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic kidney disease

Cochrane database of systematic reviews, 2020-10, Vol.10 (10), p.CD007004

2020

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Aldosterone antagonists for preventing the progression of chronic kidney disease

Cochrane database of systematic reviews, 2014-04 (4), p.CD007004-CD007004

2014

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Molecular pharmacology of the mineralocorticoid receptor: Prospects for novel therapeutics

Molecular and cellular endocrinology, 2012-03, Vol.350 (2), p.310-317

2012

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Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone

Circulation (New York, N.Y.), 2015-08, Vol.132 (5), p.402-414

2015

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Steroidal and Novel Non-steroidal Mineralocorticoid Receptor Antagonists in Heart Failure and Cardiorenal Diseases: Comparison at Bench and Bedside

Handbook of experimental pharmacology, 2017-01, Vol.243, p.271-305

2017

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Incidence, determinants, and prognostic significance of hyperkalemia and worsening renal function in patients with heart failure receiving the mineralocorticoid receptor antagonist eplerenone or placebo in addition to optimal medical therapy: results from the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF)

Circulation. Heart failure, 2014-01, Vol.7 (1), p.51-58

2014

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Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT

Health technology assessment (Winchester, England), 2024-09, Vol.28 (56), p.1-86

2024

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Influence of Baseline and Worsening Renal Function on Efficacy of Spironolactone in Patients With Severe Heart Failure: Insights From RALES (Randomized Aldactone Evaluation Study)

Journal of the American College of Cardiology, 2012-11, Vol.60 (20), p.2082-2089

2012

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Finerenone, a Novel Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Protects From Rat Cardiorenal Injury

Journal of cardiovascular pharmacology, 2014-07, Vol.64 (1), p.69-78

2014

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Effect of Spironolactone on Blood Pressure in Subjects With Resistant Hypertension

Hypertension (Dallas, Tex. 1979), 2007-04, Vol.49 (4), p.839-845

2007

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Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives

Steroids, 2017-02, Vol.118, p.76-92

2017

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CENTRAL SEROUS CHORIORETINOPATHY TREATED WITH MINERALOCORTICOID ANTAGONISTS: A ONE-YEAR PILOT STUDY

Retina (Philadelphia, Pa.), 2016-03, Vol.36 (3), p.611-618

2016

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The paradox of spironolactone: A heart failure treatment with potentially harmful effects

Journal of the Pakistan Medical Association, 2024-01, Vol.74 (2)

2024

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Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

PloS one, 2018-02, Vol.13 (2), p.e0193380

2018

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Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure)

Journal of the American College of Cardiology, 2013-10, Vol.62 (17), p.1585-1593

2013

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Citric Acid Metabolism in Resistant Hypertension: Underlying Mechanisms and Metabolic Prediction of Treatment Response

Hypertension (Dallas, Tex. 1979), 2017-11, Vol.70 (5), p.1049-1056

2017

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Comparison of eplerenone and spironolactone for the treatment of primary aldosteronism

Hypertension research, 2016-03, Vol.39 (3), p.133-137

2016

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Clinical Properties and Non-Clinical Testing of Mineralocorticoid Receptor Antagonists in In Vitro Cell Models

International journal of molecular sciences, 2024-08, Vol.25 (16), p.9088

2024

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Early eplerenone treatment in patients with acute ST-elevation myocardial infarction without heart failure: the Randomized Double-Blind Reminder Study

European heart journal, 2014-09, Vol.35 (34), p.2295-2302

2014

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Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100

Cancer research (Chicago, Ill.), 2012-05, Vol.72 (9), p.2176-2182

2012

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Influence of ejection fraction on outcomes and efficacy of spironolactone in patients with heart failure with preserved ejection fraction

European heart journal, 2016-02, Vol.37 (5), p.455-462

2016

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A randomized controlled trial of the effect of spironolactone on left ventricular mass in hemodialysis patients

Kidney international, 2019-04, Vol.95 (4), p.983-991

2019

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Examining blood pressure changes with spironolactone for alopecia: A retrospective analysis

Journal of the American Academy of Dermatology, 2024-08

2024

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Safety profile of mineralocorticoid receptor antagonists: Spironolactone and eplerenone

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic kidney disease

Aldosterone antagonists for preventing the progression of chronic kidney disease

Molecular pharmacology of the mineralocorticoid receptor: Prospects for novel therapeutics

Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone

Steroidal and Novel Non-steroidal Mineralocorticoid Receptor Antagonists in Heart Failure and Cardiorenal Diseases: Comparison at Bench and Bedside

Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT

Influence of Baseline and Worsening Renal Function on Efficacy of Spironolactone in Patients With Severe Heart Failure: Insights From RALES (Randomized Aldactone Evaluation Study)

Finerenone, a Novel Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Protects From Rat Cardiorenal Injury

Effect of Spironolactone on Blood Pressure in Subjects With Resistant Hypertension

Synthetic approaches towards the multi target drug spironolactone and its potent analogues/derivatives

CENTRAL SEROUS CHORIORETINOPATHY TREATED WITH MINERALOCORTICOID ANTAGONISTS: A ONE-YEAR PILOT STUDY

The paradox of spironolactone: A heart failure treatment with potentially harmful effects

Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion

Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure)

Citric Acid Metabolism in Resistant Hypertension: Underlying Mechanisms and Metabolic Prediction of Treatment Response

Comparison of eplerenone and spironolactone for the treatment of primary aldosteronism

Clinical Properties and Non-Clinical Testing of Mineralocorticoid Receptor Antagonists in In Vitro Cell Models

Early eplerenone treatment in patients with acute ST-elevation myocardial infarction without heart failure: the Randomized Double-Blind Reminder Study

Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100

Influence of ejection fraction on outcomes and efficacy of spironolactone in patients with heart failure with preserved ejection fraction

A randomized controlled trial of the effect of spironolactone on left ventricular mass in hemodialysis patients

Examining blood pressure changes with spironolactone for alopecia: A retrospective analysis

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