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Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2

Diabetologia, 2018-10, Vol.61 (10), p.2087-2097

2018

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Effects of SGLT2 inhibition in human kidney proximal tubular cells--renoprotection in diabetic nephropathy?

PloS one, 2013-02, Vol.8 (2), p.e54442

2013

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Glucose transporters in the small intestine in health and disease

Pflügers Archiv, 2020-09, Vol.472 (9), p.1207-1248

Koepsell, Hermann

2020

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Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia

American journal of physiology. Renal physiology, 2014-01, Vol.306 (2), p.F188-F193

2014

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SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study

Cardiovascular diabetology, 2024-05, Vol.23 (1), p.157-157, Article 157

2024

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Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models

PloS one, 2012-02, Vol.7 (2), p.e30555-e30555

2012

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LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose

The Journal of pharmacology and experimental therapeutics, 2013-05, Vol.345 (2), p.250

2013

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Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

Diabetes (New York, N.Y.), 2012-01, Vol.61 (1), p.187-196

2012

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Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2

American Journal of Physiology: Cell Physiology, 2011-01, Vol.300 (1), p.C14-C21

2011

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SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice

American journal of physiology. Renal physiology, 2014-01, Vol.306 (2), p.F194-F204

2014

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SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism

Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6416)

2018

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Effect of renal tubule-specific knockdown of the Na + /H + exchanger NHE3 in Akita diabetic mice

American journal of physiology. Renal physiology, 2019-08, Vol.317 (2), p.F419-F434

2019

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Improved glycemic control in mice lacking Sglt1 and Sglt2

American journal of physiology: endocrinology and metabolism, 2013-01, Vol.304 (2), p.E117-E130

2013

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Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats

Diabetes (New York, N.Y.), 2008-06, Vol.57 (6), p.1723-1729

2008

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Ferritinophagy activation and sideroflexin1-dependent mitochondria iron overload is involved in apelin-13-induced cardiomyocytes hypertrophy

Free radical biology & medicine, 2019-04, Vol.134, p.445-457

2019

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Knockout of Na + -glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration

American journal of physiology. Renal physiology, 2019-07, Vol.317 (1), p.F207-F217

2019

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Cardiac sodium-dependent glucose cotransporter 1 is a novel mediator of ischaemia/reperfusion injury

Cardiovascular research, 2019-09, Vol.115 (11), p.1646-1658

2019

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Sugar binding of sodium–glucose cotransporters analyzed by voltage-clamp fluorometry

The Journal of biological chemistry, 2024-05, Vol.300 (5), p.107215-107215, Article 107215

2024

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Sodium‐glucose co‐transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes

Diabetes, obesity & metabolism, 2017-09, Vol.19 (9), p.1289-1294

2017

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Genetic Evidence of Causal Relation Between Intestinal Glucose Absorption and Early Postprandial Glucose Response: A Mendelian Randomization Study

Diabetes (New York, N.Y.), 2024-06, Vol.73 (6), p.983

2024

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Dietary Glucose Increases Glucose Absorption and Lipid Deposition via SGLT1/2 Signaling and Acetylated ChREBP in the Intestine and Isolated Intestinal Epithelial Cells of Yellow Catfish

The Journal of nutrition, 2020-07, Vol.150 (7), p.1790-1798

2020

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Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine

Diabetes (New York, N.Y.), 2015-02, Vol.64 (2), p.370-382

2015

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Dapagliflozin modulates glucagon secretion in an SGLT2-independent manner in murine alpha cells

Diabetes & metabolism, 2017-12, Vol.43 (6), p.512-520

2017

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Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice

Journal of pharmacological sciences, 2020-01, Vol.142 (1), p.16-25

2020

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Gene deletion of the Na + -glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion

American journal of physiology. Renal physiology, 2019-06, Vol.316 (6), p.F1201-F1210

2019

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Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2

Effects of SGLT2 inhibition in human kidney proximal tubular cells--renoprotection in diabetic nephropathy?

Glucose transporters in the small intestine in health and disease

Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia

SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study

Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models

LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose

Na+-D-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2

SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice

SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism

Effect of renal tubule-specific knockdown of the Na + /H + exchanger NHE3 in Akita diabetic mice

Improved glycemic control in mice lacking Sglt1 and Sglt2

Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats

Ferritinophagy activation and sideroflexin1-dependent mitochondria iron overload is involved in apelin-13-induced cardiomyocytes hypertrophy

Knockout of Na + -glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration

Cardiac sodium-dependent glucose cotransporter 1 is a novel mediator of ischaemia/reperfusion injury

Sugar binding of sodium–glucose cotransporters analyzed by voltage-clamp fluorometry

Sodium‐glucose co‐transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes

Genetic Evidence of Causal Relation Between Intestinal Glucose Absorption and Early Postprandial Glucose Response: A Mendelian Randomization Study

Dietary Glucose Increases Glucose Absorption and Lipid Deposition via SGLT1/2 Signaling and Acetylated ChREBP in the Intestine and Isolated Intestinal Epithelial Cells of Yellow Catfish

Molecular mechanisms of glucose-stimulated GLP-1 secretion from perfused rat small intestine

Dapagliflozin modulates glucagon secretion in an SGLT2-independent manner in murine alpha cells

Pretreatment with KGA-2727, a selective SGLT1 inhibitor, is protective against myocardial infarction-induced ventricular remodeling and heart failure in mice

Gene deletion of the Na + -glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion

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