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Sulforaphane (Sul) reduces renal interstitial fibrosis (RIF) by controlling the inflammation and TGF-β/Smad signaling pathway

Applied Biological Chemistry, 2024, 67(0), , pp.1-11

2024

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Reduced expression of SMAD7 and consequent reduction of autophagy promotes endometrial stromal-myofibroblast transition and fibrosis

Molecular human reproduction, 2024-10, Vol.30 (10)

2024

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Schistosoma japonicum infection-mediated downregulation of lncRNA Malat1 contributes to schistosomiasis hepatic fibrosis by the Malat1/miR-96/Smad7 pathway

Parasites & vectors, 2024-10, Vol.17 (1), p.413-15, Article 413

2024

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Jiawei Taohe Chengqi Decoction attenuates CCl 4 induced hepatic fibrosis by inhibiting HSCs activation via TGF-β1/CUGBP1 and IFN-γ/Smad7 pathway

Phytomedicine (Stuttgart), 2024-10, Vol.133, p.155916

2024

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Frizzled 6 endows high‐grade serous ovarian cancer with stem‐like properties and chemoresistance

Molecular carcinogenesis, 2024-10, Vol.63 (10), p.2001-2012

2024

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TGFβ1, SMAD and β-catenin in pulmonary arteries of smokers, patients with small airway disease and COPD: potential drivers of EndMT

Clinical science (1979), 2024-09, Vol.138 (17), p.1055-1070

2024

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The Role and Mechanism of circAMOTL1 in Hypertensive Heart Failure

Journal of biomedical nanotechnology, 2024-09, Vol.20 (9), p.1519-1526

2024

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Lactucin reverses liver fibrosis by inhibiting TGF-β1/STAT3 signaling pathway and regulating short-chain fatty acids metabolism

Scientific reports, 2024-08, Vol.14 (1), p.19323-15

2024

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Aspirin attenuates the detrimental effects of TNF-α on BMMSC stemness by modulating the YAP-SMAD7 axis

Molecular medicine (Cambridge, Mass.), 2024-08, Vol.30 (1), p.126-10

2024

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Sanziguben Polysaccharides Attenuate Renal Epithelial-Mesenchymal Transition in Diabetic Nephropathy through Nrf2-Mediated Regulation of TGF-β1/Smad7 Signaling Pathway

Journal of clinical pharmacy and therapeutics, 2024-08, Vol.2024

2024

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Saponin Ⅰ from Shuitianqi () inhibits metastasis by negatively regulating the transforming growth factor-β1/Smad7 network and epithelial-mesenchymal transition in the intrahepatic metastasis Bagg's Albino/c mouse model

Journal of traditional Chinese medicine, 2024-08, Vol.44 (4), p.642-651

2024

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Enhydrin suppresses the malignant phenotype of GBM via Jun/Smad7/TGF-β1 signaling pathway

Biochemical pharmacology, 2024-08, Vol.226, p.116380, Article 116380

2024

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Deletion of GPR81 activates CREB/Smad7 pathway and alleviates liver fibrosis in mice

Molecular medicine (Cambridge, Mass.), 2024-07, Vol.30 (1), p.99-15, Article 99

2024

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Reconstitution of Natural Killer cells after allogeneic hematopoietic stem cell transplantation is facilitated by Huiyang-Guben decoction through activating the Smad7/Stat3 signal pathway

Molecular and cellular biochemistry, 2024-07, Vol.479 (7), p.1721-1733

2024

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MicroRNA-322-5p targeting Smurf2 regulates the TGF-β/Smad pathway to protect cardiac function and inhibit myocardial infarction

Human cell : official journal of Human Cell Research Society, 2024-07, Vol.37 (4), p.972-985

2024

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Knockdown of YAP1 Reduces YTHDF3 to Stabilize SMAD7 and thus Inhibit Bladder Cancer Stem Cell Stemness

Discovery medicine, 2024-07, Vol.36 (186), p.1486

2024

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SMAD7 Sustains XIAP Expression and Migration of Colorectal Carcinoma Cells

Cancers, 2024-06, Vol.16 (13), p.2370

2024

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Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosis

International journal of oral science, 2024-06, Vol.16 (1), p.48-14, Article 48

2024

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Microvesicles-delivering Smad7 have advantages over microvesicles in suppressing fibroblast differentiation in a model of Peyronie's disease

BMC biotechnology, 2024-06, Vol.24 (1), p.40-12

2024

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POS0025 ACTIVATION OF NOTCH1 SIGNALING IN FIBROBLASTS IS SUFFICIENT TO INDUCE FIBROSIS AND ACTIVATES A NETWORK OF PROFIBROTIC SIGNALING CASCADES

Annals of the rheumatic diseases, 2024-06, Vol.83 (Suppl 1), p.287-287

2024

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UHRF1 inhibition mitigates vascular endothelial cell injury and ameliorates atherosclerosis in mice via regulating the SMAD7/YAP1 axis

Molecular immunology, 2024-06, Vol.170, p.119-130

2024

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SIRT1 activation ameliorates rhesus monkey liver fibrosis by inhibiting the TGF-β/smad signaling pathway

Chemico-biological interactions, 2024-05, Vol.394, p.110979-110979, Article 110979

2024

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Mir-195-5p targets Smad7 regulation of the Wnt/β-catenin pathway to promote osteogenic differentiation of vascular smooth muscle cells

BMC cardiovascular disorders, 2024-04, Vol.24 (1), p.221-221, Article 221

2024

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Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?-A Review

Cancers, 2024-03, Vol.16 (7), p.1317

2024

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The immune regulation and therapeutic potential of the SMAD gene family in breast cancer

Scientific reports, 2024-03, Vol.14 (1), p.6769-6769, Article 6769

2024

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Sulforaphane (Sul) reduces renal interstitial fibrosis (RIF) by controlling the inflammation and TGF-β/Smad signaling pathway

Reduced expression of SMAD7 and consequent reduction of autophagy promotes endometrial stromal-myofibroblast transition and fibrosis

Schistosoma japonicum infection-mediated downregulation of lncRNA Malat1 contributes to schistosomiasis hepatic fibrosis by the Malat1/miR-96/Smad7 pathway

Jiawei Taohe Chengqi Decoction attenuates CCl 4 induced hepatic fibrosis by inhibiting HSCs activation via TGF-β1/CUGBP1 and IFN-γ/Smad7 pathway

Frizzled 6 endows high‐grade serous ovarian cancer with stem‐like properties and chemoresistance

TGFβ1, SMAD and β-catenin in pulmonary arteries of smokers, patients with small airway disease and COPD: potential drivers of EndMT

The Role and Mechanism of circAMOTL1 in Hypertensive Heart Failure

Lactucin reverses liver fibrosis by inhibiting TGF-β1/STAT3 signaling pathway and regulating short-chain fatty acids metabolism

Aspirin attenuates the detrimental effects of TNF-α on BMMSC stemness by modulating the YAP-SMAD7 axis

Sanziguben Polysaccharides Attenuate Renal Epithelial-Mesenchymal Transition in Diabetic Nephropathy through Nrf2-Mediated Regulation of TGF-β1/Smad7 Signaling Pathway

Saponin Ⅰ from Shuitianqi () inhibits metastasis by negatively regulating the transforming growth factor-β1/Smad7 network and epithelial-mesenchymal transition in the intrahepatic metastasis Bagg's Albino/c mouse model

Enhydrin suppresses the malignant phenotype of GBM via Jun/Smad7/TGF-β1 signaling pathway

Deletion of GPR81 activates CREB/Smad7 pathway and alleviates liver fibrosis in mice

Reconstitution of Natural Killer cells after allogeneic hematopoietic stem cell transplantation is facilitated by Huiyang-Guben decoction through activating the Smad7/Stat3 signal pathway

MicroRNA-322-5p targeting Smurf2 regulates the TGF-β/Smad pathway to protect cardiac function and inhibit myocardial infarction

Knockdown of YAP1 Reduces YTHDF3 to Stabilize SMAD7 and thus Inhibit Bladder Cancer Stem Cell Stemness

SMAD7 Sustains XIAP Expression and Migration of Colorectal Carcinoma Cells

Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosis

Microvesicles-delivering Smad7 have advantages over microvesicles in suppressing fibroblast differentiation in a model of Peyronie's disease

POS0025 ACTIVATION OF NOTCH1 SIGNALING IN FIBROBLASTS IS SUFFICIENT TO INDUCE FIBROSIS AND ACTIVATES A NETWORK OF PROFIBROTIC SIGNALING CASCADES

UHRF1 inhibition mitigates vascular endothelial cell injury and ameliorates atherosclerosis in mice via regulating the SMAD7/YAP1 axis

SIRT1 activation ameliorates rhesus monkey liver fibrosis by inhibiting the TGF-β/smad signaling pathway

Mir-195-5p targets Smad7 regulation of the Wnt/β-catenin pathway to promote osteogenic differentiation of vascular smooth muscle cells

Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?-A Review

The immune regulation and therapeutic potential of the SMAD gene family in breast cancer

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