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Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis

The Journal of clinical investigation, 2017-10, Vol.127 (10), p.3770-3783

2017

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LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway

Ecotoxicology and environmental safety, 2020-12, Vol.205, p.111327-111327, Article 111327

2020

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Long noncoding RNA OPA‐interacting protein 5 antisense transcript 1 upregulated SMAD3 expression to contribute to metastasis of cervical cancer by sponging miR‐143‐3p

Journal of cellular physiology, 2019-04, Vol.234 (4), p.5264-5275

2019

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TGF‐β transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 and ERK/Sp1 signaling pathways

Molecular oncology, 2018-03, Vol.12 (3), p.305-321

2018

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GRK2 promotes activation of lung fibroblast cells and contributes to pathogenesis of pulmonary fibrosis through increasing Smad3 expression

American Journal of Physiology: Cell Physiology, 2022-01, Vol.322 (1), p.C63-C72

2022

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Mir‐29b promotes human aortic valve interstitial cell calcification via inhibiting TGF‐β3 through activation of wnt3/β‐catenin/Smad3 signaling

Journal of cellular biochemistry, 2018-07, Vol.119 (7), p.5175-5185

2018

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Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis

British journal of pharmacology, 2018-07, Vol.175 (13), p.2689-2708

2018

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Transforming growth factor‐β signalling in renal fibrosis: from Smads to non‐coding RNAs

The Journal of physiology, 2018-08, Vol.596 (16), p.3493-3503

2018

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circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway

Molecular cancer, 2020-02, Vol.19 (1), p.23-23, Article 23

2020

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Expression of Transforming Growth Factor β1, Smad3, and Phospho-Smad3 in Somatotropinomas and Their Relationship to Tumor Behavior

World neurosurgery, 2021-09, Vol.153, p.e20-e27

2021

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ATOH8 binds SMAD3 to induce cellular senescence and prevent Ras-driven malignant transformation

Proceedings of the National Academy of Sciences - PNAS, 2023-01, Vol.120 (3), p.e2208927120

2023

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Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis

Laboratory investigation, 2019-03, Vol.99 (3), p.346-357

2019

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Endoplasmic reticulum stress promotes sepsis‐induced muscle atrophy via activation of STAT3 and Smad3

Journal of cellular physiology, 2023-03, Vol.238 (3), p.582-596

2023

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Brachyury promotes extracellular matrix synthesis through transcriptional regulation of Smad3 in nucleus pulposus

American Journal of Physiology: Cell Physiology, 2024-05, Vol.326 (5), p.C1384-C1397

2024

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Upregulated SMAD3 promotes epithelial–mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma

Laboratory investigation, 2014-06, Vol.94 (6), p.683-691

2014

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miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling

Molecular therapy, 2014-05, Vol.22 (5), p.974-985

2014

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TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis

Molecular therapy, 2018-01, Vol.26 (1), p.148-161

2018

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Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling

Genes & development, 2019-11, Vol.33 (21-22), p.1506-1524

2019

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Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

Journal of allergy and clinical immunology, 2017-08, Vol.140 (2), p.534-542

2017

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MiR-195 Suppresses Cervical Cancer Migration and Invasion Through Targeting Smad3

International journal of gynecological cancer, 2016-06, Vol.26 (5), p.817-824

2016

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The long non-coding RNA GAS5 regulates transforming growth factor β (TGF-β)–induced smooth muscle cell differentiation via RNA Smad–binding elements

The Journal of biological chemistry, 2017-08, Vol.292 (34), p.14270-14278

2017

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MALAT1 Modulates TGF-β1-Induced Endothelial-to-Mesenchymal Transition through Downregulation of miR-145

Cellular physiology and biochemistry, 2017, Vol.42 (1), p.357-372

2017

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Downregulated microRNA‐330 suppresses left ventricular remodeling via the TGF‐β1/Smad3 signaling pathway by targeting SRY in mice with myocardial ischemia–reperfusion injury

Journal of cellular physiology, 2019-07, Vol.234 (7), p.11440-11450

2019

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Deciphering the complex role of thrombospondin-1 in glioblastoma development

Nature communications, 2019-03, Vol.10 (1), p.1146-1146, Article 1146

2019

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Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis

LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway

Long noncoding RNA OPA‐interacting protein 5 antisense transcript 1 upregulated SMAD3 expression to contribute to metastasis of cervical cancer by sponging miR‐143‐3p

TGF‐β transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 and ERK/Sp1 signaling pathways

GRK2 promotes activation of lung fibroblast cells and contributes to pathogenesis of pulmonary fibrosis through increasing Smad3 expression

Mir‐29b promotes human aortic valve interstitial cell calcification via inhibiting TGF‐β3 through activation of wnt3/β‐catenin/Smad3 signaling

Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis

Transforming growth factor‐β signalling in renal fibrosis: from Smads to non‐coding RNAs

A mutation update on the LDS‐associated genes TGFB2/3 and SMAD2/3

circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway

Expression of Transforming Growth Factor β1, Smad3, and Phospho-Smad3 in Somatotropinomas and Their Relationship to Tumor Behavior

ATOH8 binds SMAD3 to induce cellular senescence and prevent Ras-driven malignant transformation

Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis

Endoplasmic reticulum stress promotes sepsis‐induced muscle atrophy via activation of STAT3 and Smad3

Brachyury promotes extracellular matrix synthesis through transcriptional regulation of Smad3 in nucleus pulposus

Upregulated SMAD3 promotes epithelial–mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma

miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling

TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis

Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling

Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

MiR-195 Suppresses Cervical Cancer Migration and Invasion Through Targeting Smad3

The long non-coding RNA GAS5 regulates transforming growth factor β (TGF-β)–induced smooth muscle cell differentiation via RNA Smad–binding elements

MALAT1 Modulates TGF-β1-Induced Endothelial-to-Mesenchymal Transition through Downregulation of miR-145

Downregulated microRNA‐330 suppresses left ventricular remodeling via the TGF‐β1/Smad3 signaling pathway by targeting SRY in mice with myocardial ischemia–reperfusion injury

Deciphering the complex role of thrombospondin-1 in glioblastoma development

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